Rchr
J-GLOBAL ID：202101002423007482
Update date: Feb. 27, 2024
Yoshino Takashi
Yoshino Takashi
Affiliation and department：
Job title：
Specially Appointed Associate Professor
Research field (1)：
Developmental biology
Research keywords (10)：
ヒトiPS細胞
, mouse embryo
, Organoid
, Embryonic stem cells
, Coelomic epithelium
, Gonadal somatic cells
, 精巣
, Ovary
, Chick embryo
, Lateral plate mesoderm
Research theme for competitive and other funds (4)：
- 2022 - 2025 マウス多能性幹細胞からの機能的な精巣オルガノイドの構築
- 2020 - 2022 マウスES細胞から完全再構築した生殖巣オルガノイドを用いた性スペクトラムの理解
- 2019 - 2022 Oocyte production with the set of ovarian follcle progenitors induced from mouse ESCs
- 2016 - 2018 Reconstitution of oocyte production system from pluripotent stem cells
Papers (10)：
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Katsuhiko Hayashi, Takashi Yoshino. Reconstitution of reproductive organ system that produces functional oocytes. Current opinion in genetics & development. 2022. 77. 101982-101982
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Takashi Yoshino, Takahiro Suzuki, Go Nagamatsu, Haruka Yabukami, Mika Ikegaya, Mami Kishima, Haruka Kita, Takuya Imamura, Kinichi Nakashima, Ryuichi Nishinakamura, et al. Generation of ovarian follicles from mouse pluripotent stem cells. Science (New York, N.Y.). 2021. 373. 6552
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Takashi Yoshino, Daisuke Saito. Epithelial-to-mesenchymal transition-based morphogenesis of dorsal mesentery and gonad. Seminars in cell & developmental biology. 2019. 92. 105-112
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Takashi Yoshino, Hidetaka Murai, Daisuke Saito. Hedgehog-BMP signalling establishes dorsoventral patterning in lateral plate mesoderm to trigger gonadogenesis in chicken embryos. Nature communications. 2016. 7. 12561-12561
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Teruaki Takahashi, Yuta Takase, Takashi Yoshino, Daisuke Saito, Ryosuke Tadokoro, Yoshiko Takahashi. Angiogenesis in the developing spinal cord: blood vessel exclusion from neural progenitor region is mediated by VEGF and its antagonists. PloS one. 2015. 10. 1. e0116119
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MISC (3)：
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吉野 剛史, 斉藤 大介, 高橋 淑子. Epithelial-to-mesenchymal transition is regulated by an intrinsic program and environmental cues: a study with coelomic epithelium as a novel model). 日本発生生物学会・日本細胞生物学会合同大会要旨集. 2007. 40回・59回. 67-67
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吉野 剛史, 仲矢 由紀子, 高橋 淑子. 【形と運動を司る細胞のダイナミクス 最新技術による分子機構の解明から疾患治療への展開まで】 細胞と形態形成・疾患 からだ作りにみる上皮-間充織転換. 実験医学. 2006. 24. 13. 2032-2040
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吉野 剛史, 長谷川 武宏, 佐藤 有紀, 高橋 淑子. 核移行を指標としたNotchシグナルの可視化. 日本細胞生物学会大会講演要旨集. 2002. 55回. 65-65
Patents (1)：
-
CULTURE TECHNIQUE FOR DIFFERENTIATING OVARIAN TISSUE FROM PLURIPOTENT STEM CELLS
Books (6)：
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性腺オルガノイドによる性スペクトラムの理解
北隆館 (月刊「細胞」) 2024
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Cell biology of the ovary : stem cells, development, cancer, and clinical aspects
Springer 2018 ISBN:9789811079405
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側板中胚葉の器官形成と上皮-間充織転換
秀潤社(細胞工学) 2014
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器官形成をささえるEMT
秀潤社(細胞工学) 2008
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形態形成と上皮-間葉系転換
羊土社 (実験医学) 2006
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Lectures and oral presentations (6)：
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Recapitulation of gonadal sex determination process using murine embryonic stem cells
(9th International Symposium on the Biology of Vertebrate Sex Determination 2023)
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In vitro reconstitution of murine ovarian follicles
(Cold Spring Harbor Asia meeting, Human Development - from Embryos to Stem Cell Models Pre-meeting Webinar 2022)
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Study of chicken embryonic coelomic mesoderm and mouse ovarian organoid reconstitution
(Riken BDR seminar 2022)
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Elucidation and reconstitution of gonadal somatic cell specification machineries in chicken and mouse
(Riken BDR seminar 2021)
-
Hedgehog-BMP4 signaling orchestrates the onset of gonadogenesis associated with embryonic patterning in vertebrates
(The Ovary 2016)
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Education (1)：
- 2006 - 2011 Nara Institute of Science and Technology
Awards (3)：
- 2023 - 9th International Symposium on the Biology of Vertebrate Sex Determination Travel award
- 2022 - 武田科学振興財団 医学系研究継続助成(基礎) マウス多能性幹細胞からの機能的な生殖巣オルガノイドの構築
- 2019 - 武田科学振興財団 医学系研究助成〈基礎〉 誘導胎児卵巣細胞を用いての機能的な卵子作出
Association Membership(s) (1)：
Japanesd Society of Developmental Biology
