Shimada Tadayuki

シマダタダユキ | Shimada Tadayuki

Research theme for competitive and other funds (9)：

2022 - 2025 神経-グリア間相互作用の調節を通じた、社会行動の制御メカニズム
2017 - 2021 Regulatory mechanism of depression and anxiety via the control of axonal branch formation
2012 - 2016 Role of clutch protein shootin1 in activity-dependent axonal elongation
2008 - 2010 Mechanism of Neuronal Polarization Mediated by Shootin and Its Roles in the Brain
2007 - 2008 新規タンパク質shootin1を中心とした軸索伸長を司る基本メカニズムの解析

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Papers (19)：

Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori, et al. Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. eLife. 2024. 12
Hiroko Sugiura, Tadayuki Shimada, Keiko Moriya-Ito, Jun-Ichi Goto, Hiroki Fujiwara, Rie Ishii, Hiroshi Shitara, Choji Taya, Satoshi Fujii, Toshiyuki Kobayashi, et al. A Farnesyltransferase Inhibitor Restores Cognitive Deficits in Tsc2^+/- Mice through Inhibition of Rheb1. The Journal of Neuroscience. 2022. 42. 12. 2598-2612
Tadayuki Shimada, Kanato Yamagata. Spine morphogenesis and synapse formation in tubular sclerosis complex models. Frontiers in molecular neuroscience. 2022. 15. 1019343-1019343
Chihiro Hisatsune, Tadayuki Shimada, Akitoshi Miyamoto, Amy Lee, Kanato Yamagata. Tuberous sclerosis complex (TSC) inactivation increases neuronal network activity by enhancing Ca2+ influx via L-type Ca2+ channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2021
Tadayuki Shimada, Shin Yasuda, Hiroko Sugiura, Kanato Yamagata. Syntenin: PDZ Protein Regulating Signaling Pathways and Cellular Functions. International journal of molecular sciences. 2019. 20. 17

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MISC (25)：

島田忠之, 山形要人. 結節性硬化症モデルマウスにおける、アストロサイトの活性化に起因した神経機能の異常. てんかん研究. 2023. 41. 2. 278-278
島田忠之, 山形要人. ニューロサイエンスの最新情報てんかんの難治化因子neuritin. Clinical Neuroscience. 2021. 39. 12. 1588-1590
後藤純一, 山形要人, 島田忠之, 藤原浩樹, 山崎良彦, 藤井聡. 結節性硬化症原因遺伝子欠損マウスにおけるシナプス可塑性異常の改善に向けたアプローチ. 山形大学紀要医学(Web). 2019. 37. 1
久恒智博, 島田忠之, 山形要人. TSC2欠損型ヒトiPS細胞由来の神経細胞にみられる神経ネットワーク異常. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
山形要人, 島田忠之, 杉浦弘子. Screening of new therapeutic compounds for tuberous sclerosis complex. てんかん治療研究振興財団研究年報. 2019. 30

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