Rchr
J-GLOBAL ID：202101002981164284   Update date: Jun. 28, 2024

Nemoto Kiyomitsu

ネモト キヨミツ | Nemoto Kiyomitsu
Affiliation and department：
Nihon University Research Institute of Pharmacy

About Nihon University Research Institute of Pharmacy


Job title： Senior Research Fellow
Research field  (5)： Pharmaceuticals - health and biochemistry ,  Molecular biology ,  Cell biology ,  Environmental and pharmaceutical development resources ,  Neuroscience - general
Research keywords  (7)： 毒性学 ,  発がん ,  分子生物学 ,  細胞生物学 ,  神経科学 ,  認知症 ,  機能性食品
Research theme for competitive and other funds  (12)：
  • 2016 - 2019 Basic research for application of nobiletin, a citrus peel constituent, in improvement and/or prevention of dementia
  • 2011 - 2015 Study on a role of NMDA receptor in chemical-induced hepatotoxicity
  • 2005 - 2006 Study on toxic effects of endocrine disruptors and their species-, gender-, and age-related differences
  • 2002 - 2004 Study on Expression and Function of Neurotrophins and their Receptors in Non-Neuronal Tissues
  • 2002 - 2003 環境化学物質による非神経組織障害と神経栄養因子誘導との関連
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Papers (98)：
  • Masahiko Tebakari, Yuki Daigo, Hiroaki Takemoto, Kiyomitsu Nemoto, Fumihide Takano. Sphingolipid-Enriched Porcine Placental Extract Promotes the Expression of Structural Genes and Desquamation Enzyme Genes in Cultured Human Keratinocytes. Biological and Pharmaceutical Bulletin. 2024. 47. 6. 1231-1238
  • Wei Dai, Kotaro Ishibashi, Hiroaki Takemoto, Saki Ito, Hikaru Kasuya, Tadaaki Sato, Takashi Saito, Takaomi C. Saido, Kiyomitsu Nemoto. Increased Expression of C/EBP Homologous Protein, a Marker of Endoplasmic Reticulum Stress, in the Brains of AppNL-G-F/NL-G-F Knock-in Alzheimer’s Disease Model Mice. BPB Reports. 2024. 7. 2. 44-50
  • Misaki Kojima, Daiichiro Fuchimoto, Shiro Yamashita, Akira Onishi, Masakuni Degawa, Kiyomitsu Nemoto. Effect of Growth Hormone Receptor Deficiency on Androgen-Associated Gene Expression of Hepatic Drug Metabolizing Enzymes and Drug Transporters in Pigs. Biological & Pharmaceutical Bulletin. 2023. 46. 9. 1338-1342
  • Misaki Kojima, Masakuni Degawa, Kiyomitsu Nemoto. Androgen-Dependent Expression of CUX2 mRNA in the Pig Liver Is Associated with That of Drug Metabolizing Enzymes and Drug Transporters. Biological and Pharmaceutical Bulletin. 2023. 46. 3. 482-487
  • Yuichiro Kanno, Nao Saito, Ryota Saito, Tomohiro Kosuge, Ryota Shizu, Tomofumi Yatsu, Takuomi Hosaka, Kiyomitsu Nemoto, Keisuke Kato, Kouichi Yoshinari. Differential DNA-binding and cofactor recruitment are possible determinants of the synthetic steroid YK11-dependent gene expression by androgen receptor in breast cancer MDA-MB 453 cells. Experimental cell research. 2022. 419. 2. 113333-113333
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MISC (19)：
  • 菅野 裕一朗, 日下部 太一, 吉川 晶子, 谷津 智史, 青柳 果蓮, 早野 友華里, 東屋 功, 加藤 恵介, 根本 清光. 選択的アンドロゲン受容体調節薬YK11のジアステレオ混合物の単一化、およびその活性の評価. 日本薬学会年会要旨集. 2018. 138年会. 3. 129-129
  • 谷津 智史, 日下部 太一, 加藤 恵介, 根本 清光, 菅野 裕一朗. 選択的アンドロゲン受容体調節薬(17α,20E)-17,20-[(1-Methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic Acid Methyl Ester(YK11)のアンドロゲン受容体(AR)を介する骨形成促進作用. 日本薬学会年会要旨集. 2017. 137年会. 3. 61-61
  • 谷津 智史, 菅野 裕一朗, 日下部 太一, 加藤 恵介, 井上 義雄, 根本 清光. 選択的アンドロゲン受容体調節薬YK11による骨分化促進作用. 日本薬学会年会要旨集. 2016. 136年会. 3. 136-136
  • 李 巍, 菅野 裕一朗, 谷津 智史, 今井 美由紀, 鹿島 真奈美, 井上 義雄, 根本 清光, 小池 一男. 生薬沢瀉由来のプロトスタン型トリテルペンの核内受容体PXRアゴニスト活性. 日本生薬学会年会講演要旨集. 2015. 62回. 67-67
  • 池田絢香, 副島早織, 森惇貴, 横須賀章人, 三巻祥浩, 金子雪子, 石川智久, 関本征史, 根本清光, 大泉康, et al. 柑橘類果皮成分ノビレチンによるAMPKの活性化. 日本薬学会年会要旨集(CD-ROM). 2014. 134th
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Education (3)：
  • 1985 - 1986 Tokyo University of Science Graduate School of Pharmaceutical Sciences
  • 1983 - 1985 Tokyo University of Science Graduate School of Pharmaceutical Sciences
  • 1979 - 1983 Tokyo University of Science Faculty of Pharmaceutical Sciences Department of Pharmacy
Work history (6)：
  • 2024/04 - 現在 Nihon University Research Institute of Pharmacy
  • 2015/04 - 2024/03 Toho University Faculty of Pharmaceutical Sciences
  • 2007/01 - 2015/03 University of Shizuoka School of Pharmaceutical Sciences
  • 2003/11 - 2006/12 University of Shizuoka School of Pharmaceutical Sciences
  • 1992/04 - 2003/10 University of Shizuoka School of Pharmaceutical Sciences
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Association Membership(s) (6)：
高血圧関連疾患モデル学会 ,  日本毒性学会 ,  日本分子生物学会 ,  日本癌学会 ,  日本生化学会 ,  日本薬学会
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