Takahashi Tokiharu

タカハシトキハル | Takahashi Tokiharu

Affiliation and department：
Job title： Professor and Chair

Research field (5)： Evolutionary biology , Developmental biology , Genomics , Anatomy , Hematology and oncology

Research keywords (7)： Evolutionary Developmental Biology , Comparative Anatomy , Amphioxus , Alx homeobox gene family , Homeobox genes , Vertebrates , Chordates

Research theme for competitive and other funds (14)：

2022 - 2026 The evolutionary origin of the vertebrate pharyngeal arches
2001 - 2003 DEVELOPMENT OF IMMUNOTHERAPY To HEMATOLOGIC MALIGNANCIES
2000 - 2001 新しい造血肝細胞体外増幅法の実用化
2000 - 2000 造血器腫瘍に対するシグナル伝達分子を用いた次世代造血幹細胞増幅法の開発
1999 - 2000 Notch in hematopoiesis

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Papers (40)：

Ali Al-Azzawi, Tokiharu Takahashi. Anatomical variations of the thyroid gland: An experimental cadaveric study. Annals of Medicine and Surgery. 2021. 70. 102823-102823
Huijia Wang, Peter W. H. Holland, Tokiharu Takahashi. Gene profiling of head mesoderm in early zebrafish development: insights into the evolution of cranial mesoderm. EvoDevo. 2019. 10. 1. 1-14
Donna Page, Raphael Thuret, Lakshmi Venkatraman, Tokiharu Takahashi, Katie Bentley, Shane Herbert. Positive-feedback defines the timing, magnitude and robustness of angiogenesis. Cell Reports. 2019. 27. 11. 3139-3151
Tokiharu Takahashi, et al. Amphioxus functional genomics and the origins of vertebrate gene regulation. Nature. 2018. 564. 64-70
Arda Cetinkaya, Jingwei Rachel Xiong, İbrahim Vargel, Kemal Kösemehmetoğlu, Halil İbrahim Canter, Ömer Faruk Gerdan, Nicola Longo, Ahmad Alzahrani, Mireia Perez Camps, Ekim Zihni Taşkıran, et al. Loss-of-Function Mutations in ELMO2 Cause Intraosseous Vascular Malformation by Impeding RAC1 Signaling. American Journal of Human Genetics. 2016. 99. 2. 299-317

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MISC (3)：

Tokiharu Takahashi. Amphioxus and the evolutionary origins of vertebrate traits: from Florida to South France and Xiamen. 生体の科学. 2019. 70. 4. 1-6
高橋宗春. シグナル伝達分子を用いた造血幹細胞増幅の可能性. 医学のあゆみ. 1997. 180. 13. 992-996
T Takahashi, T Tanaka, K Kumano, M Kurokawa, N Hirano, K Sasaki, H Honda, S Chiba, Saito, I, Y Shibata, et al. A novel molecular approach to ex vivo expansion of hematopoietic progenitors using an adenovirus vector. BLOOD. 1996. 88. 10. 3930-3930

Education (5)：

1992 - 1996 The University of Tokyo Graduate School of Medicine
1991 - 1992 Tokyo Kosei Nenkin Hospital Resident (Internal Medicine)
1990 - 1991 The University of Tokyo Faculty of Medicine University Hospital Resident (Internal Medicine)
1986 - 1990 The University of Tokyo Faculty of Medicine School of Medicine
1984 - 1986 The University of Tokyo College of Arts and Sciences

Professional career (1)：

MD, PhD (The University of Tokyo)

Work history (8)：

2021/07 - 現在 Tokyo Medical University Department of Histology and Neuroanatomy Professor and Chair
2016/08 - 2021/06 The University of Manchester Faculty of Biology, Medicine and Health Lecturer in Anatomy
2007/01 - 2016/08 The University of Manchester Faculty of Life Sciences Lecturer in Anatomy
2003/01 - 2006/12 University of Oxford Department of Zoology Research Fellow/Senior Research Fellow
2001/08 - 2003/01 The University of Reading School of Animal & Microbial Sciences Royal Society (London)/JSPS Bilateral Exchange Programme Researcher

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Committee career (1)：

2021/09 - 現在日本解剖学会代議員

Association Membership(s) (7)：

日本解剖学会 , Society for Molecular Biology & Evolution , International Zebrafish Society , Anatomical Society , International Society of Developmental Biologists , European Evolutionary Developmental Biology , British Society for Developmental Biology

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