YOSHIHARA Masaharu

ヨシハラマサハル | YOSHIHARA Masaharu

Affiliation and department：
Job title： Assistant Professor

Research field (7)： Molecular biology , Cell biology , Genetics , Morphology, anatomy , Developmental biology , Laboratory animal science , Anatomy

Research keywords (6)： Gross Anatomy , Histology , Developmental Biology , Delta-Notch signaling pathway , Morphogenesis , Transgenic Mouse

Research theme for competitive and other funds (4)：

2023 - 2028 Deciphering heart development via Notch1 signaling
2022 - 2024 Elucidation of a morphogenic mechanism via Delta-Notch signaling pathway- an in vivo examination of a mathematical prediction of biliary formation
2022 - 2023 Identification of Notch1 signaling- receiving cell lineage during acute kidney injury in a mouse sepsis model
2021 - 2022 Mathematical and bioengineering examination of biliary development via Delta-Notch signaling

Papers (11)：

Masaharu Yoshihara, Yoshitoku Watabe, Momo Morikawa, Suguru Iwata, Michito Hamada, Tetsuya Sasaki, Noriko Homma, Yosuke Takei. A case report of an Adachi-Williams type CG plus H aortic arch anomaly and implications for the development of the cervicothoracic circulation. Folia Morphologica. 2024
Tomohiko Sato, Kenichi Yoshida, Tsutomu Toki, Rika Kanezaki, Kiminori Terui, Ryunosuke Saiki, Masami Ojima, Yotaro Ochi, Seiya Mizuno, Masaharu Yoshihara, et al. Landscape of driver mutations and their clinical effects on Down syndrome-related myeloid neoplasms. Blood Journal. 2024. 143. 25. 2627-2643
Masaharu Yoshihara, Takahiro Nakayama, Satoru Takahashi. Chromatin accessibility analysis suggested vascular induction of the biliary epithelium via the Notch signaling pathway in the human liver. BMC Research Notes. 2023. 16. 1. 379
Masaharu Yoshihara, Satoru Takahashi. Recent advances in in situ Notch signaling measurement. Frontiers in cell and developmental biology. 2023. 11. 1244105-1244105
Naoto Sambe, Masaharu Yoshihara, Teppei Nishino, Ryosuke Sugiura, Takahiro Nakayama, Chandra Louis, Satoru Takahashi. Analysis of Notch1 signaling in mammalian sperm development. BMC Research Notes. 2023. 16. 1. 108

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MISC (2)：

Teppei Nishino, Masaharu Yoshihara. Deciphering the pattern formation mechanism via Delta-Notch signaling pathway -Evidence from mathematical analysis of liver development. Journal of Clinical and Experimental Medicine. 2022. 280. 11. 1167-1168
Masatsugu Ema, Masaharu Yoshihara. Screening of angiogenesis-regulatory factors in embryo. Vascular Biology and Medicine. 2014. 14. 4. 359-367

Lectures and oral presentations (11)：

Quantitative evaluation of signal transduction by using transgenic mice
(The 112th Kanto Area Annual Meeting of the Japanese Association of Anatomists 2024)
Notch1 signaling in the cardiac development
(The 112th Kanto Area Annual Meeting of the Japanese Association of Anatomists 2024)
Analysis of Notch1 signaling dynamics in the kidney under sepsis using newly developed transgenic mice
(The 70th Annual Meeting of the Japanese Association for Laboratory Animal Science 2023)
Infectious disease and cadaver bodies
(The 24th meeting for anatomical research and training 2023)
An college student life - perspectives of an anatomist / ER physician
(Annual meeting of scholarship recipients in 2022 (Ibaraki Prefecture, Japan) 2022)

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Works (1)：

Attracted in human body development (YouTube videoclip of Council of Head of National Medical Schools of Japan)
Masaharu Yoshihara 2021 -

Education (2)：

2019 - 2023 University of Tsukuba School of Integrative and Global Majors PhD Program in Humanics
2011 - 2017 University of Tsukuba School of Medicine and Medical Sciences

Professional career (2)：

Work history (4)：

2022/04 - 現在 Department of Primary Care and Medical Education, Faculty of Medicine, University of Tsukuba Assistant Professor
2021/04 - 2022/03 Japan Society for the Promotion of Science Young Scientist Fellow (DC1)
2019/04 - 2021/03 University of Tsukuba Research Assistant
2017/04 - 2019/03 Tsukuba Medical Center Foundation junior resident physician

Committee career (9)：

2024/10 - 現在 College of Medicine, University of Tsukuba Member of Subcommittee of Basic Medicine
2024/09 - 現在 University of Tsukuba Member of Student Support Committee of Ph.D. Program in Humanics
2024/05 - 現在 Medical Education Center, College of Medicine, University of Tsukuba Member
2024/04 - 現在 Ph.D. Program in Humanics, University of Tsukuba Student Support Team Member
2024/04 - 現在 College of Medicine, University of Tsukuba Medical Education Committee Member

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Awards (3)：

2024/04 - College of Medicine, School of Medicine and Health Sciences, University of Tsukuba Best Teachers’ Award
2023/11 - Institute of Medicine, University of Tsukuba Outstanding Faculty Member
2023/04 - College of Medicine, School of Medicine and Health Sciences, University of Tsukuba Best Teachers' Award

Association Membership(s) (2)：

Japanese Association for Laboratory Animal Science , The Japanese Association of Anatomists

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