Kodama Masami

コダママサミ | Kodama Masami

Affiliation and department：
Research theme for competitive and other funds (6)：

2021 - 2024 Structural analysis of the gating mechanism of cardiac ryanodine receptor
2021 - 2024 GCase受容体の構造生物学ーリガンドの認識機構と結合シグナルの分子内伝達機構
2018 - 2021 Roles of molecular complex of IKs channel in plasma membrane depolarization - relaxation coupling in cardiac myocytes
2015 - 2019 Multidisciplinary approach to cardiac arrhythmogenesis assessment during drug discovery
2014 - 2017 交感神経系刺激応答の性差に関わる心血管シグナル調節機構の網羅的解析

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Papers (14)：

Haruo Ogawa, Masami Kodama. Structural insight into hormone recognition by the natriuretic peptide receptor-A. The FEBS Journal. 2024. 291. 10. 2273-2286
Ryosuke Ishida, Nagomi Kurebayashi, Hiroto Iinuma, Xi Zeng, Shuichi Mori, Masami Kodama, Takashi Murayama, Hiroyuki Masuno, Fumi Takeda, Masatoshi Kawahata, et al. A potent and selective cis-amide inhibitor of ryanodine receptor 2 as a candidate for cardiac arrhythmia treatment. European journal of medicinal chemistry. 2023. 262. 115910-115910
Mai Takenaka, Masami Kodama, Takashi Murayama, Mari Ishigami-Yuasa, Shuichi Mori, Ryosuke Ishida, Junji Suzuki, Kazunori Kanemaru, Masami Sugihara, Masamitsu Iino, et al. Screening for Novel Type 2 Ryanodine Receptor Inhibitors by Endoplasmic Reticulum Ca²⁺Monitoring. Molecular Pharmacology. 2023. 104. 6. 275-286
Takuya Kobayashi, Akihisa Tsutsumi, Nagomi Kurebayashi, Saito K, Kodama M, Takashi Sakurai, Masahide Kikkawa, Takashi Murayama, Haruo Ogawa. Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nature communications. 2022
Kodama M, Kazuharu Furutani, Kimura R, Ando T, Sakamoto K, Shushi Nagamori, Ashihara T, Kurachi Y, Sekino Y, Furukawa T, et al. Systematic expression analysis of genes related to generation of action potentials in human iPS cell-derived cardiomyocytes. Journal of pharmacological sciences. 2019

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MISC (8)：

児玉昌美, 清水聡史, 坂本多穗, 黒川洵子. 検査値・薬物動態での性差. 月間薬事. 2024. 66. 2. 297-301
清水聡史, 児玉昌美, 坂本多穗, 黒川洵子. 薬物動態と薬力学における性差. 日本臨床. 2023. 81. 7. 961-966
小川治夫, 児玉昌美. ナトリウム利尿ペプチド受容体の基質認識とその活性化機構. 循環器内科. 2021. 89. 4. 454-462
木村彩瑛, 稲田理毅, 児玉昌美, 永森收志, 岩本隆宏, 喜多紗斗美, 山崎泰広, 黒川洵子. 心筋IKsチャネルのCa2+感受性における分子複合体の役割. 応用薬理. 2019. 96. 5-6. 129-129
Junko Kurokawa, Yasunari Kanda, Masami Kodama, Yuko Sekino, Tetsushi Furukawa. Effects of Anticancer Drugs on Contractile Behaviors of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocyte Monolayers Evaluated with an Image-based Analysis Using Motion Field Imaging Technique. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS. 2017. 88. 187-188

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Lectures and oral presentations (3)：

機能既知化合物ライブラリーからスクリーニングした新規RyR2阻害薬の抗不整脈作用
(第95回日本薬理学会年会 2022)
The origin of sex differences in morphology of embryonic murine coronary arteries.
(International and Interdisciplinary Symposium 2016 2016)
Ser-Pro site of p53Ser46 is phosphorylated by ATM.
(International Workshop on Ataxia-Telangiectasia (A-T) and ATM 2008)

Education (3)：

1998 - 2002 東京大学大学院理学系研究科博士課程生物化学専攻
1996 - 1998 東京大学大学院理学系研究科修士課程生物化学専攻
1991 - 1996 The University of Tokyo Faculty of Science Department of Biophysics and Biochemistry

Work history (11)：

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