Rchr
J-GLOBAL ID：202101004102442961   Update date: Oct. 17, 2024

Xie Lin

シャ リン | Xie Lin
Affiliation and department：
National Institutes for Quantum and Radiological Science and Technology

About National Institutes for Quantum and Radiological Science and Technology


Research field  (3)： Immunology ,  Tumor diagnostics and therapeutics ,  Radiology
Research keywords  (7)： Immunotherapeutic Efficacy Assessment ,  Nuclear Medicine ,  Theranostics ,  Molecular Imaging ,  Targeted Radionuclide Therapy (TRT) ,  PET ,  Radiopharmaceuticals
Research theme for competitive and other funds  (13)：
  • 2023 - 2027 Development of New Positron Emission Tomography Probes for Imaging PDE7
  • 2021 - 2024 キレーター含有糖ユニットで修飾した抗体の標識反応と評価
  • 2021 - 2024 mGluR1を標的とするα線Radio-theranosticsシステムの確立
  • 2020 - 2024 Development of PET probes for gama 8-dependent transmembrane AMPA receptor regulatory protein
  • 2019 - 2023 Development of positron emission tomography tracers evaluating the safety and oncotherapy effect for photodynamic therapy
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Papers (97)：
  • Yiding Zhang, Lin Xie, Masayuki Fujinaga, Yusuke Kurihara, Masanao Ogawa, Katsushi Kumata, Wakana Mori, Tomomi Kokufuta, Nobuki Nengaki, Hidekatsu Wakizaka, et al. L-[5-11C]Glutamine PET imaging noninvasively tracks dynamic responses of glutaminolysis in non-alcoholic steatohepatitis. Acta Pharmaceutica Sinica B. 2024
  • Siqi Zhang, Xiaohui Ma, Jiang Wu, Jieting Shen, Yuntao Shi, Xingkai Wang, Lin Xie, Xiaona Sun, Yuxuan Wu, Hao Tian, et al. Enhanced radiotheranostic targeting of integrin α5β1 with PEGylation-enabled peptide multidisplay platform (PEGibody): A strategy for prolonged tumor retention with fast blood clearance. Acta Pharmaceutica Sinica B. 2024
  • Zhongshan He, Wei Chen, Kuan Hu, Yaoyao Luo, Wanqin Zeng, Xi He, Tingting Li, Jiang Ouyang, Yongjiang Li, Lin Xie, et al. Resolvin D1 delivery to lesional macrophages using antioxidative black phosphorus nanosheets for atherosclerosis treatment. Nature Nanotechnology. 2024
  • Zhen Chen, Jiahui Chen, Wakana Mori, Yongjia Yi, Jian Rong, Yinlong Li, Erick R Calderon Leon, Tuo Shao, Zhendong Song, Tomoteru Yamasaki, et al. Preclinical Evaluation of Novel Positron Emission Tomography (PET) Probes for Imaging Leucine-Rich Repeat Kinase 2 (LRRK2). Journal of medicinal chemistry. 2024. 67. 4. 2559-2569
  • Jian Rong, Tomoteru Yamasaki, Yinlong Li, Katsushi Kumata, Chunyu Zhao, Ahmed Haider, Jiahui Chen, Zhiwei Xiao, Masayuki Fujinaga, Kuan Hu, et al. Development of Novel 11C-Labeled Selective Orexin-2 Receptor Radioligands for Positron Emission Tomography Imaging. ACS medicinal chemistry letters. 2023. 14. 10. 1419-1426
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MISC (15)：
  • 謝琳, 破入正行, 張一鼎, 藤永雅之, 峯岸克行, 大久保崇之, 永津弘太郎, 下川卓志, 足助一真, 張明栄. mGluR1陽性ヒト癌に対する211At-AITMによる標的アイソトープ治療の検証. 核医学(Web). 2023. 60. Supplement
  • 破入正行, 謝琳, 張一鼎, 森昌子, 筒井正斗, 水野真盛, 張明栄. 糖鎖加水分解パニツムマブの標識合成と体内動態. 日本抗体学会学術大会プログラム・抄録集(Web). 2022. 1st
  • 謝琳, 破入正行, 藤永雅之, 張一鼎, 張露露, 森若菜, 胡寛, 峯岸克行, 永津弘太郎, 張明栄. 癌蛋白質mGluR1に基づくラジオセラノスティクス薬剤の開発. 核医学(Web). 2022. 59. Supplement
  • 破入正行, 謝琳, 張一鼎, 峯岸克行, 門間あゆみ, 門間あゆみ, HU Kuan, 藤永雅之, 永津弘太郎, 石岡典子, et al. TRT薬剤211At-AITM誘導体の合成と評価. 核医学(Web). 2022. 59. Supplement
  • 河村和紀, 山崎友照, 平石惇人, 藤永雅之, 栗原雄祐, 栗原雄祐, 小川政直, 小川政直, 塚越海渡, 塚越海渡, et al. 光感受性物質であるADPM06の18F標識合成及びインビボ評価. 核医学(Web). 2022. 59. Supplement
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Education (1)：
  • 2008 - 2011 Osaka University Graduate School of Medicine
Professional career (1)：
  • M.D., PhD (Osaka University)
Work history (6)：
  • 2024/07 - 現在 National Institutes for Quantum Science and Technology Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Science
  • 2019/07 - 2024/06 National Institutes for Quantum Science and Technology Senior Researcher(Permanent Employee)
  • 2018/04 - 2019/06 National Institutes for Quantum and Radiological Science and Technology Department of Advanced Nuclear Medicine Sciences, National Institute of Radiological Sciences Researcher(Permanent Employee)
  • 2016/04 - 2018/03 National Institutes for Quantum and Radiological Science and Technology Researcher (tenure)
  • 2014/04 - 2016/03 National Institute of Radiological Sciences Department of Molecular Probes, Molecular Imaging Center Researcher
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Awards (12)：
  • 2024/01 - Takeda Science Foundation Excellent Poster Award
  • 2024/01 - The Life Science Association of Chinese in Japan Excellent Research Award
  • 2022/12 - 生物学部門 優秀展示賞
  • 2015/11 - Association of Chinese Alumni in Japan Life Science Award
  • 2015/07 - 学会賞
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Association Membership(s) (5)：
European Association of Nuclear Medicine ,  World Molecular Imaging Society ,  Society of Nuclear Medicine and Molecular Imaging ,  Japanese Society for Molecular Imaging ,  The Japanese Society of Nuclear Medicine
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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