Rchr
J-GLOBAL ID：202101004319999840
Update date: Aug. 03, 2023
MURAKAWA Tomokazu
ムラカワ トモカズ | MURAKAWA Tomokazu
Affiliation and department：
Job title：
Assistant Professor
Research theme for competitive and other funds (4)：
- 2022 - 2024 心臓におけるミトコンドリア分解制御機構の解明と心不全治療薬創薬に向けた基礎的検討
- 2021 - 2023 Bcl2-L-13の心臓におけるマイトファジー制御機構の解明と創薬への応用
- 2015 - 2018 Integrated analyses of mitochondria degradation system as a novel therapeutic target of heart failure
- 2015 - 2018 Regulatory mechanism of mitochondria dynamics during progression of cardiac reverse remodeling
Papers (32)：
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Ryuta Sugihara, Manabu Taneike, Tomokazu Murakawa, Takahito Tamai, Hiromichi Ueda, Rika Kitazume-Taneike, Takafumi Oka, Yasuhiro Akazawa, Hiroki Nishida, Kentaro Mine, et al. Lysophosphatidylserine induces necrosis in pressure overloaded male mouse hearts via G protein coupled receptor 34. Nature communications. 2023. 14. 1. 4494-4494
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Yasuhiro Akazawa, Manabu Taneike, Hiromichi Ueda, Rika Kitazume-Taneike, Tomokazu Murakawa, Ryuta Sugihara, Hiroki Yorifuji, Hiroki Nishida, Kentaro Mine, Ayana Hioki, et al. Rubicon-regulated beta-1 adrenergic receptor recycling protects the heart from pressure overload. Scientific reports. 2022. 12. 1. 41-41
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Hajime Abe, Yohei Tanada, Shigemiki Omiya, Mihai-Nicolae Podaru, Tomokazu Murakawa, Jumpei Ito, Ajay M Shah, Simon J Conway, Masahiro Ono, Kinya Otsu. NF-κB activation in cardiac fibroblasts results in the recruitment of inflammatory Ly6Chi monocytes in pressure-overloaded hearts. Science signaling. 2021. 14. 704. eabe4932
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Jumpei Ito, Shigemiki Omiya, Mara-Camelia Rusu, Hiromichi Ueda, Tomokazu Murakawa, Yohei Tanada, Hajime Abe, Kazuki Nakahara, Michio Asahi, Manabu Taneike, et al. Iron derived from autophagy-mediated ferritin degradation induces cardiomyocyte death and heart failure in mice. eLife. 2021. 10
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Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, Marie H Abildgaard, Yakubu Princely Abudu, Abraham Acevedo-Arozena, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021. 17. 1. 1-382
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MISC (148)：
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種池 学, 村川 智一, 大津 欣也. 【基礎科学の進歩】循環器疾患とオートファジー. 循環器専門医. 2021. 30. 66-72
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村川 智一, 大津 欣也. 【心不全のサイエンス 治療法開発をめざして心臓の謎を解く】(第2章)心疾患・心不全の分子病態の最先端 心臓リモデリングにおけるオートファジーの役割. 実験医学. 2019. 37. 5. 719-724
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Tomokazu Murakawa, Osamu Yamaguchi, Koji Okamoto, Yasushi Sakata, Kinya Otsu. The Novel Mitophagic Receptor Protein, Bcl2-like Protein 13: New Insights for the Molecular Mechanisms of the Pathogenesis of Heart Disease. JOURNAL OF CARDIAC FAILURE. 2015. 21. 10. S147-S147
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肥後 友彰, 廣谷 信一, 小笠原 延行, 柏瀬 一路, 平田 明生, 岡田 佳築, 村川 智一, 根本 貴祥, 松井 万智子, 松尾 浩志, et al. 腎梗塞で発症し、診断までに時間を要した感染性心内膜炎の一例. Circulation Journal. 2008. 72. Suppl.III. 1112-1112
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松井 万智子, 肥後 友彰, 松尾 浩志, 樫山 智一, 増村 雄喜, 和田 暢, 岡田 佳築, 村川 智一, 根本 貴祥, 平田 明生, et al. たこつぼ型心筋症発症時の心電図変化を経時的に記録できた一例. Circulation Journal. 2008. 72. Suppl.III. 1102-1102
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Professional career (1)：
- Doctor of Philosophy (Osaka University)
Work history (2)：
- 2021/06 - 現在 Osaka University Graduate School of Medicine Department of Cardiovascular Medicine Assistant Professor
- 2020/12 - 現在 Osaka University Graduate School of Medicine Department of Medical Therapeutics for Heart Failure Assistant Professor
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