Rchr
J-GLOBAL ID：202101005091932453
Update date: Sep. 27, 2024
Isozumi Noriyoshi
Isozumi Noriyoshi
Affiliation and department：
Job title：
Assistant Professor
Research field (3)：
Structural biochemistry
, Pharmaceuticals - analytical and physicochemistry
, Neurology
Research theme for competitive and other funds (2)：
- 2024 - 2028 神経変性疾患の治療法開発に向けた亜鉛フィンガードメインの新たな機能の解明
- 2020 - 2023 揺らいだ分子構造の植物病原菌エフェクターDN3の機能発現機構
Papers (28)：
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Honoka Kawamukai, Motonori Matsusaki, Takanari Tanimoto, Mai Watabe, Ken Morishima, Shunsuke Tomita, Yoichi Shinkai, Tatsuya Niwa, Taro Mannen, Hiroyuki Kumeta, Hitoki Nanaura, Kotona Kato, Takuya Mabuchi, Yuichiro Aiba, Takeru Uehara, Noriyoshi Isozumi, Yoshika Hara, Shingo Kanemura, Hiroyoshi Matsumura, Kazuma Sugie, Koichiro Ishimori, Takahiro Muraoka, Masaaki Sugiyama, Masaki Okumura, Eiichiro Mori, Takuya Yoshizawa, Tomohide Saio. Conserved loop of a phase modifier endows protein condensates with fluidity. bioRxiv. 2024
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Kazuki Fujita, Noriyoshi Isozumi, Qiunan Zhu, Masaya Matsubayashi, Tetsuya Taniguchi, Hiroshi Arakawa, Yoshiyuki Shirasaka, Eiichiro Mori, Ikumi Tamai. Unique Binding Sites of Uricosuric Agent Dotinurad for Selective Inhibition of Renal Uric Acid Reabsorptive Transporter URAT1. Journal of Pharmacology and Experimental Therapeutics. 2024. 390. 1. 99-107
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Naohiko Iguchi, Noriyoshi Isozumi, Yoshikazu Hattori, Tomohiro Imamura, Masatomo So, Hitoki Nanaura, Takao Kiriyama, Nobuyuki Eura, Minako Yamaoka, Mari Nakanishi, et al. Zinc finger domains bind low-complexity domain polymers. bioRxiv. 2023
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Jing Gu, Noriyoshi Isozumi, Bin Gao, Shinya Ohki, Shunyi Zhu. Mutation-driven evolution of antibacterial function in an ancestral antifungal scaffold: Significance for peptide engineering. Frontiers in Microbiology. 2022. 13. 1053078-1053078
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Tomo Shiota, Riko Nagata, Sotaro Kikuchi, Hitoki Nanaura, Masaya Matsubayashi, Mari Nakanishi, Shinko Kobashigawa, Noriyoshi Isozumi, Takao Kiriyama, Kazuaki Nagayama, et al. C9orf72-Derived Proline:Arginine Poly-Dipeptides Modulate Cytoskeleton and Mechanical Stress Response. Frontiers in Cell and Developmental Biology. 2022. 10. 750829-750829
ｍore...
MISC (1)：
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Noriyoshi Isozumi, Kazuma Sugie, Eiichiro Mori. Biological phase separation in neuromuscular diseases. Clinical Neurology. 2023. 63. 12
Lectures and oral presentations (2)：
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Zinc finger domains bind low-complexity domain polymers
(The 8th LLPS Symposium/ The Biophysical Society of Japan Joint Seminar “Toward establishing LLPS research systems” 2024)
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The role of zinc finger domains in biological phase separation
(4th Japan-UK Neuroscience Symposium 2022 2022)
Work history (4)：
- 2023/04 - 現在 Nara Medical University Future Basic Medicine Assistant Professor
- 2021/11 - 2023/03 Nara Medical University Future Basic Medicine Assistant Professor
- 2017/04 - 2021/09 Japan Advanced Institute of Science and Technology Center for Nano Materials and Technology Postdoctral Fellow
- 2013/07 - 2017/03 Osaka University Graduate School of Medicine Postdoctral Fellow
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