Rchr
J-GLOBAL ID：202101005189934870
Update date: Feb. 01, 2024
Hayashi Tomoatsu
ハヤシ トモアツ | Hayashi Tomoatsu
Affiliation and department：
Job title：
Project Research Associate
Research field (3)：
Molecular biology
, Tumor biology
, Systems genomics
Research keywords (5)：
Brain cancer
, Ovarian cancer
, Cancer stem cells
, Single cell analysis
, Bioinformatics
Research theme for competitive and other funds (6)：
Papers (25)：
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Kenzui Taniue, Takeaki Oda, Tomoatsu Hayashi, Yuki Kamoshida, Yasuko Takeda, Anzu Sugawara, Yuki Shimoura, Lumi Negishi, Takeshi Nagashima, Mariko Okada-Hatakeyama, et al. LncRNA ZNNT1 induces p53 degradation by interfering with the interaction between p53 and the SART3-USP15 complex. PNAS Nexus. 2023
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Yoko Akasu-Nagayoshi, Tomoatsu Hayashi, Ayako Kawabata, Naomi Shimizu, Ai Yamada, Naoko Yokota, Ryuichiro Nakato, Katsuhiko Shirahige, Aikou Okamoto, Tetsu Akiyama. PHOSPHATE exporter XPR1/SLC53A1 is required for the tumorigenicity of epithelial ovarian cancer. Cancer Science. 2022
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Ayako Kawabata, Tomoatsu Hayashi, Yoko Akasu-Nagayoshi, Ai Yamada, Naomi Shimizu, Naoko Yokota, Ryuichiro Nakato, Katsuhiko Shirahige, Aikou Okamoto, Tetsu Akiyama. CRISPR/Cas9 Screening for Identification of Genes Required for the Growth of Ovarian Clear Cell Carcinoma Cells. Current Issues in Molecular Biology. 2022. 44. 4. 1587-1596
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Ken Matsuura, Shizuka Kobayashi, Kohtarou Konno, Miwako Yamasaki, Takahiro Horiuchi, Takao Senda, Tomoatsu Hayashi, Kiyotoshi Satoh, Fumiko Arima-Yoshida, Kei Iwasaki, et al. SIPA1L1/SPAR1 interacts with the neurabin family of proteins and is involved in GPCR signaling. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022. 42. 12. 2448-2473
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Brandon Cona, Tomoatsu Hayashi, Ai Yamada, Naomi Shimizu, Naoko Yokota, Ryuichiro Nakato, Katsuhiko Shirahige, Tetsu Akiyama. The splicing factor DHX38/PRP16 is required for ovarian clear cell carcinoma tumorigenesis, as revealed by a CRISPR-Cas9 screen. FEBS open bio. 2021. 12. 3. 582-593
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Books (3)：
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がん幹細胞の理解に向けたシングルセル解析 (がん微小環境に1細胞レベルで挑む : 技術革新で見えてきた腫瘍内の細胞と免疫応答の多様性、がん悪性化・治療抵抗性の鍵)
羊土社 2021 ISBN:9784758103961
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細胞系譜軌跡推定ツールとそのアルゴリズムについて (ダイレクトリプログラミング : 再生医療の新展開)
エヌ・ティー・エス 2020 ISBN:9784860436711
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シングルセル遺伝子発現解析からみえてきた腫瘍内不均一性 (シングルセルゲノミクス : 組織の機能, 病態が1細胞レベルで見えてきた!)
羊土社 2019 ISBN:9784758103831
Lectures and oral presentations (10)：
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Understanding tumor heterogeneity in epithelial ovarian cancer by single cell RNA sequencing
(The 4th Research Conference of Research Society for Cancer 3-D Culture 2022)
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Identification and analysis of genes required for the growth of ovarian cancer cells by CRISPR/Cas9 screening
(The 81th Annual Meeting of the Japanese Cancer Association 2022)
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シングルセルRNA-seq解析とCYTOF解析による抗腫瘍免疫応答の理解
(第三回WAKO Web受託セミナー ~一分子解析の進歩と活用実例~ 2020)
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がん多様性の1細胞解析
(新学新術領域研究「細胞社会ダイバーシティーの統合的解明と制御」 第五回公開シンポジウム 2020)
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やってみよう!single cell RNA-seq解析ことはじめ
(イルミナiSchool プロフェッショナル 2019)
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Education (1)：
- 2002 - 2007 The University of Tokyo Graduate School of Agricultural and Life Sciences Biotechnology
Work history (3)：
- 2018/04 - 現在 The University of Tokyo Institute for Quantitative Biosciences Project Research Associate
- 2011/04 - 2018/03 The University of Tokyo Laboratory of Molecular and Genetic Information, Institute of Molecular and Cellular Biosciences Research Associate
- 2007/03 - 2011/03 The University of Tokyo Laboratory of Molecular and Genetic Information, Institute of Molecular and Cellular Biosciences Project Researcher
Association Membership(s) (3)：
The Molecular Biology Society of Japan
, The Japanese Association for Molecular Target Therapy of Cancer
, Japanese Cancer Association
