Ueda Naoko

ウエダナオコ | Ueda Naoko

Research field (3)： Molecular biology , Cell biology , Functional biochemistry

Research keywords (11)：ヘビ毒 , タンパク質 , ホスホリパーゼA2 , 遺伝子 , 分子進化 , ベノミクス , ゲノミクス , トランスクリプトミクス , 転写調節 , 細胞外小胞 , アポトーシス

Research theme for competitive and other funds (7)：

2019 - 2022 加速進化により多様性を獲得したハブ毒遺伝子の発現と毒分泌の分子メカニズムの解明
2013 - 2017 Study on structure, function and gene regulation of Protobothrops flavoviridis snake venom phospholipase A2 isozymes
2010 - 2012 Molecular mechanisms of transcriptional regulationProitnobothrops flavoviridis venom gland.
2006 - 2007 Molecular mechanisms in regulation of gene expression in Protobothrops flavoviridis venom gland.
2004 - 2005 Elucidation of DNA replication mechanism of Protobothrops flavoviridis (Habu snake)

Show all

Papers (56)：

Moeka Yoshikawa, Hitomi Nakamura, Naoko Oda-Ueda, Tadashi Ueda, Takatoshi Ohkuri. Effect of an intermolecular disulfide bond introduced into the first loop of CH1 domain of Adalimumab Fab on thermal stability and antigen-binding activity. The Journal of Biochemistry. 2022. 172. 1. 49-56
Hitomi Nakamura, Moeka Yoshikawa, Naoko Oda-Ueda, Tadashi Ueda, Takatoshi Ohkuri. A comprehensive analysis of novel disulfide bond introduction site into the constant domain of human Fab. Scientific reports. 2021. 11. 1. 12937-12937
Hitomi Nakamura, Masato Kiyoshi, Makoto Anraku, Noritaka Hashii, Naoko Oda-Ueda, Tadashi Ueda, Takatoshi Ohkuri. Glycosylation decreases aggregation and immunogenicity of adalimumab Fab secreted from Pichia pastoris. Journal of biochemistry. 2021. 169. 4. 435-443
Kento Inamaru, Ami Takeuchi, Marie Maeda, Hiroki Shibata, Yasuyuki Fukumaki, Naoko Oda-Ueda, Shosaku Hattori, Motonori Ohno, Takahito Chijiwa. Discovery of the Gene Encoding a Novel Small Serum Protein (SSP) of Protobothrops flavoviridis and the Evolution of SSPs. Toxins. 2020. 12. 3
Hitomi Nakamura, Makoto Anraku, Naoko Oda-Ueda, Tadashi Ueda, Takatoshi Ohkuri. C-Terminal Cysteine PEGylation of Adalimumab Fab with an Engineered Interchain SS Bond. Biological & pharmaceutical bulletin. 2020. 43. 3. 418-423

ｍore...

MISC (84)：

稲丸賢人, 竹内亜美, 前田真理恵, 柴田弘紀, 服巻保幸, 上田直子, 服部正策, 大野素徳, 千々岩崇仁. Analysis of the array of small serum protein genes of Protobothrops flavoviridis snake. 爬虫両棲類学会報. 2020. 2020. 1
中村仁美, 大栗誉敏, 服部正策, 上田直子. Neutralizing effects of monoclonal antibodies against the myotoxic factor (BPII) from Protobothrops flavoviridis venom and the development of related Fab fragments. 日本薬学会年会要旨集(CD-ROM). 2020. 140th
松井崇, 鎌田しずか, 石井健太郎, 丸野孝浩, ガーネムノーラン, 内山進, 内山進, 加藤晃一, 加藤晃一, 加藤晃一, et al. Structure analysis of phospholipase A₂ analogue and its SDS-induced oligomerization. 量子ビームサイエンスフェスタ(Web). 2019. 2018
柴田弘紀, 千々岩崇仁, 上田直子, 服部正策, 松原和純, 松田洋一, 久田香奈子, 将口栄一, 佐藤矩行, 小川智久. ハブ(Protobothrops flavoviridis)の全ゲノム解析から明らかになった毒液関連遺伝子群の多重化および加速進化と染色体構造との関係. 爬虫両棲類学会報. 2019. 2019. 1
角野歩, 角野歩, 神谷孫斗, 上田直子. 高速原子間力顕微鏡によるハブ毒液由来ホスホリパーゼA₂の脂質膜分解動態の観察. トキシンシンポジウム予稿集. 2019. 66th

ｍore...

Professional career (1)：

Work history (6)：

Show all

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page