Sera Takashi

Research theme for competitive and other funds (13)：

2022 - 2025 新規人工RNA結合タンパク質の革新的デザイン法の開発とその有効性の検証
2019 - 2022 Development of innovative design method for new artificial RNA-binding proteins
2016 - 2019 Development of a site-specific gene integration method to human genomes
2014 - 2017 Development of artificial transcription factors for the treatment of lung and esophageal squamous cell carcinoma
2013 - 2016 Generation of plants resistant to DNA viruses using artificial DNA-binding proteins

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Papers (10)：

Kento Nakamura, Taishu Nakao, Tomoaki Mori, Serika Ohno, Yusuke Fujita, Keisuke Masaoka, Kazuki Sakabayashi, Koichi Mori, Takamasa Tobimatsu, Takashi Sera. Necessity of Flanking Repeats R1′ and R8′ of Human Pumilio1 Protein for RNA Binding. Biochemistry. 2021. 60. 40. 3007-3015
Tomoaki Mori, Chiaki Warner, Serika Ohno, Koichi Mori, Takamasa Tobimatsu, Takashi Sera. Genome sequence analysis of new plum pox virus isolates from Japan. BMC Research Notes. 2021. 14. 1. 266-266
Tatsuhiko Sumikawa, Serika Ohno, Takeharu Watanabe, Ryo Yamamoto, Miyu Yamano, Tomoaki Mori, Koichi Mori, Takamasa Tobimatsu, Takashi Sera. Site-specific integration by recruitment of a complex of ΦC31 integrase and donor DNA to a target site by using a tandem, artificial zinc-finger protein. Biochemistry. 2018. 57. 50. 6868-6877
Etsuko Yokota, Tomoki Yamatsuji, Munenori Takaoka, Minoru Haisa, Nagio Takigawa, Noriko Miyake, Tomoko Ikeda, Tomoaki Mori, Serika Ohno, Takashi Sera, et al. Targeted silencing of SOX2 by an artificial transcription factor showed antitumor effect in lung and esophageal squamous cell carcinoma. Oncotarget. 2017. 8. 61. 103063-103076
Tomoaki Mori, Kento Nakamura, Keisuke Masaoka, Yusuke Fujita, Ryosuke Morisada, Koichi Mori, Takamasa Tobimatsu, Takashi Sera. Cleavage of influenza RNA by using a human PUF-based artificial RNA-binding protein-staphylococcal nuclease hybrid. Biochemical and Biophysical Research Communications. 2016. 479. 4. 736-740

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Professional career (1)：

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