Rchr
J-GLOBAL ID:202101005937458334   Update date: Feb. 01, 2024

Umeki Nobuhisa

ウメキ ノブヒサ | Umeki Nobuhisa
Affiliation and department:
Job title: Research Scientist
Research field  (3): Cell biology ,  Biophysics ,  Functional biochemistry
Research keywords  (3): 細胞運動 ,  細胞内情報伝達 ,  1分子蛍光イメージング
Research theme for competitive and other funds  (6):
  • 2023 - 2027 変異アクチンの新規調製法の確立と疾病メカニズム解明に向けたアプローチ
  • 2018 - 2022 分子認識反応における、R-Rasに特徴的なN末およびC末領域の役割
  • 2013 - 2017 The novel molecular recognition mechanism of Ras by its structural polymorphism
  • 2013 - 2016 低分子量Gタンパク質Rasの構造多型性と疾病との関連性
  • 2013 - 2014 細胞膜上で二量体化したRasの新規情報伝達メカニズム
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Papers (28):
  • Takuya Imaizumi, Nobuhisa Umeki, Ryo Yoshizawa, Tomoyuki Obuchi, Yasushi Sako, Yoshiyuki Kabashima. Assessing transfer entropy from biochemical data. Physical review. E. 2022. 105. 3-1. 034403-034403
  • Ryo Yoshizawa, Nobuhisa Umeki, Akihiro Yamamoto, Mariko Okada, Masayuki Murata, Yasushi Sako. p52Shc regulates the sustainability of ERK activation in a RAF-independent manner. Molecular biology of the cell. 2021. mbcE21010007
  • Ryo Yoshizawa, Nobuhisa Umeki, Akihiro Yamamoto, Masayuki Murata, Yasushi Sako. Biphasic spatiotemporal regulation of GRB2 dynamics by p52SHC for transient RAS activation. Biophysics and physicobiology. 2021. 18. 1-12
  • Nobuhisa Umeki, Keitaro Shibata, Taro Q P Noguchi, Keiko Hirose, Yasushi Sako, Taro Q P Uyeda. K336I mutant actin alters the structure of neighbouring protomers in filaments and reduces affinity for actin-binding proteins. Scientific reports. 2019. 9. 1. 5353-5353
  • Yuki Nakamura, Nobuhisa Umeki, Mitsuhiro Abe, Yasushi Sako. Mutation-Specific Mechanisms of Hyperactivation of Noonan Syndrome SOS Molecules Detected with Single-molecule Imaging in Living Cells. Scientific reports. 2017. 7. 1. 14153-14153
more...
Professional career (1):
  • Ph.D. (Niigata University)
Work history (3):
  • 2012/10 - 現在 RIKEN
  • 2009/11 - 2012/09 National Institute of Advanced Industrial Science and Technology
  • 2006/05 - 2009/10 University of Massachusetts Medical School
Awards (1):
  • 2022 - The Biophysical Society of Japan Biophysics and Physicobiology Editors' Choice Award Biphasic spatiotemporal regulation of GRB2 dynamics by p52SHC for transient RAS activation
Association Membership(s) (2):
日本生化学会 ,  The Biophysical Society of Japan
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