Research theme for competitive and other funds (5):
2023 - 2028 Studies on innovative technology for modification of structural skeleton of natural products and production of artificial novel natural compounds
2019 - 2023 Fermentative production of rare natural compounds found in marine organisms living in the seas of Thailand
2019 - 2021 Study on the synthetic biological approach toward fermentative production of rare-natural products from unculturable and symbiotic microorganisms
Papers (9):
Takehiro Nishimura, Kei Kudo, Miho Izumikawa, Ikuko Kozone, Junko Hashimoto, Noritaka Kagaya, Hikaru Suenaga, Koh Takeuchi, Kazuo Shin-ya. Isolation and Structure Elucidation of JBIR-157, a Skeletally Novel Aromatic Polyketide Produced by the Heterologous Expression of a Cryptic Gene Cluster. Chemical and Pharmaceutical Bulletin. 2024. 72. 5. 475-479
Kei Kudo, Takehiro Nishimura, Miho Izumikawa, Ikuko Kozone, Junko Hashimoto, Manabu Fujie, Hikaru Suenaga, Haruo Ikeda, Nori Satoh, Kazuo Shin-ya. Capability of a large bacterial artificial chromosome clone harboring multiple biosynthetic gene clusters for the production of diverse compounds. The Journal of Antibiotics. 2024. 77. 5. 288-298
Atina Rizkiya Choirunnisa, Kuga Arima, Yo Abe, Noritaka Kagaya, Kei Kudo, Hikaru Suenaga, Junko Hashimoto, Manabu Fujie, Noriyuki Satoh, Kazuo Shin-ya, et al. New azodyrecins identified by a genome mining-directed reactivity-based screening. Beilstein Journal of Organic Chemistry. 2022. 18. 1017-1025
Chao Liu, Junko Hashimoto, Kei Kudo, Kazuo Shin-Ya, Hideaki Kakeya. An Atypical Arginine Dihydrolase Involved in the Biosynthesis of Cyclic Hexapeptide Longicatenamides. Chemistry, an Asian journal. 2021. 16. 11. 1382-1387
Kei Kudo, Takehiro Nishimura, Ikuko Kozone, Junko Hashimoto, Noritaka Kagaya, Hikaru Suenaga, Haruo Ikeda, Kazuo Shin-Ya. Hemiacetal-less rapamycin derivatives designed and produced by genetic engineering of a type I polyketide synthase. Scientific reports. 2021. 11. 1. 9944-9944