Rchr
J-GLOBAL ID：202101007021238323
Update date: Sep. 17, 2024
Tajima Ayasa
タジマ アヤサ | Tajima Ayasa
Affiliation and department：
Research field (4)：
Nutrition and health science
, Cell biology
, Metabolism and endocrinology
, Molecular biology
Research keywords (5)：
Docosa Hexaenoic Acid
, Lipid metabolism
, ATP citrate lyase
, antizyme
, polyamine
Research theme for competitive and other funds (5)：
- 2024 - 2027 ポリアミンバランスの破綻がもたらす細胞死メカニズムの解析
- 2024 - 2025 がん促進因子のリン酸化プロテオミクスによる創薬ターゲットの探索
- 2022 - 2024 ドコサヘキサエン酸の酸化代謝物による抗動脈硬化作用の分子生物学的機序の解析
- 2023 - ポリアミン輸送システムの解明による新たなアンチエイジング戦略の確立
- 2017 - 2020 Elucidation of the relationship between polyamine synthesis and fatty acid synthesis in obesity formation and the investigation of drug targets
Papers (6)：
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Saishu Yoshida, Akira Kawamura, Katsuhiko Aoki, Pattama Wiriyasermkul, Shinya Sugimoto, Junnosuke Tomiyoshi, Ayasa Tajima, Yamato Ishida, Yohei Katoh, Takehiro Tsukada, et al. Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 28. e2320070121
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Yaqi Li, Ayasa Tajima, Floyd J Mattie, Michael H Green, A Catharine Ross. Pregnancy and Lactation Alter Vitamin A Metabolism and Kinetics in Rats under Vitamin A-Adequate Dietary Conditions. Nutrients. 2021. 13. 8
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Takahiko J Fujimi, Yoshihiro Mezaki, Takahiro Masaki, Ayasa Tajima, Mariko Nakamura, Akira Yoshikawa, Noriyuki Murai, Mamoru Aizawa, Soichi Kojima, Yoshihiro Matsumoto, et al. Investigation of the effects of urea cycle amino acids on the expression of ALB and CEBPB in the human hepatocellular carcinoma cell line FLC-4. Human cell. 2020. 33. 3. 590-598
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Yaqi Li, Ayasa Tajima, Floyd Mattie, Erin Dexheimer, Elizabeth Soucy, Michael Green, A. Catharine Ross. Pregnancy and Lactation Alter Vitamin A Metabolism and Kinetics in Rats under Vitamin A-Adequate Dietary Conditions. Current Developments in Nutrition. 2020. 4. nzaa041_024-nzaa041_024
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Noriyuki Murai, Yasuko Murakami, Ayasa Tajima, Senya Matsufuji. Novel ubiquitin-independent nucleolar c-Myc degradation pathway mediated by antizyme 2. Scientific reports. 2018. 8. 1. 3005-3005
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MISC (2)：
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マクロファージのコレステロール輸送に対するDHAの影響 (第138回成医会総会一般演題). 2021. 136. 6. 139-140
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Interaction between Antizyme and ATP citrate lyase in cancer cells. 2015. 130. 6. 166-166
Lectures and oral presentations (13)：
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ATP citrate lyase suppresses the cell death of ornithine decarboxylase-overproducing cells
(International Conference on the Biological Roles of Polyamines 2024, 7th Yamada Symposium 2024)
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ポリアミン過剰産生が引き起こす細胞死における ATP クエン酸リアーゼの役割
(日本ポリアミン学会第 14 回年会 2023)
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教育講演
(第20回ポリアミンと核酸の共進化シンポジウム 2023)
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ATP citrate lyase suppresses the cell death of ornithine decarboxylase-overproducing cell line
(Gordon Research Conference on Polyamines 2023)
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Docosahexaenoic acid suppresses the generation of reactive oxygen species in endothelial cells: a role for retinoid X receptor RXR
(22nd IUNS-International Congress of Nutrition 2022)
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Professional career (1)：
Work history (2)：
- 2016 - 現在 The Jikei University School of Medicine Department of Molecular Biology
- 2019 - 2020 The Pennsylvania State University Department of Nutritional Sciences Postdoctoral Scholar
Committee career (2)：
- 2023/04 - 現在 The Japanese Society of Polyamine Research Public Relations staff
- 2016/04 - 現在 The Japanese Society of Polyamine Research staff
Awards (3)：
- 2017 - Travel Grant from The Yukio Miyamoto Society of Japan
- 2015 - Young Researcher Travel Grant from The Japanese Society of Polyamine Research
- 2011 - The Japanese Society of Polyamine Research Young Researcher Travel Grant from The Japanese Society of Polyamine Research
Association Membership(s) (5)：
日本薬学会
, 日本動脈硬化学会
, 日本生化学会
, Japan Society of Nutrition and Food Science
, The Japanese Society of Polyamine Research
