MIURA TAICHI

ミウラタイチ | MIURA TAICHI

Affiliation and department：
Job title：主任研究員

Research field (4)： Radiology , Cell biology , Cell biology , Molecular biology

Research keywords (4)：放射線消化管障害 , 間葉系幹細胞 , 多能性幹細胞 , 糖鎖

Research theme for competitive and other funds (4)：

2020 - 2023 Analysis of the effect of regenerative therapy on radiation intestinal damage by intestinal organoids.
2018 - 2022 Mechanism of function of FGF that selects cells in normal tissues and protects them from radiation damage.
2020 - 2020 放射線腸管障害に対するミューズ細胞の治療効果の解析
2015 - 2016 細胞質唯一の糖鎖修飾である O-GlcNAc による多能性幹細胞のナイーブ状態とプライム状態の制御機構の解明

Papers (17)：

Taichi Miura, Mitsuko Kawano, Keiko Takahashi, Noriyuki Yuasa, Masato Habu, Fumie Kimura, Toru Imamura, Fumiaki Nakayama. High-Sulfated Hyaluronic Acid Ameliorates Radiation-Induced Intestinal Damage Without Blood Anticoagulation. Advances in Radiation Oncology. 2022. 7. 3. 100900-100900
Hirohito Abo, Masahiko Kume, Federico Pecori, Taichi Miura, Naoki Matsumoto, Shoko Nishihara, Kazuo Yamamoto. Disaccharide-tag for highly sensitive identification of O-GlcNAc-modified proteins in mammalian cells. PloS one. 2022. 17. 5. e0267804
Federico Pecori, Ikuko Yokota, Hisatoshi Hanamatsu, Taichi Miura, Chika Ogura, Hayato Ota, Jun-ichi Furukawa, Shinya Oki, Kazuo Yamamoto, Osamu Yoshie, et al. A defined glycosylation regulatory network modulates total glycome dynamics during pluripotency state transition. Scientific Reports. 2021. 11. 1
Federico Pecori, Nanako Kondo, Chika Ogura, Taichi Miura, Masahiko Kume, Youhei Minamijima, Kazuo Yamamoto, Shoko Nishihara. Site-specific O-GlcNAcylation of Psme3 maintains mouse stem cell pluripotency by impairing P-body homeostasis. Cell Reports. 2021. 36. 2. 109361-109361
Taichi Miura, Noriyuki Yuasa, Hayato Ota, Masato Habu, Mitsuko Kawano, Fumiaki Nakayama, Shoko Nishihara. Highly sulfated hyaluronic acid maintains human induced pluripotent stem cells under feeder-free and bFGF-free conditions. Biochemical and Biophysical Research Communications. 2019. 518. 3. 506-512

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Lectures and oral presentations (57)：

出血を誘発しない高硫酸化ヒアルロン酸の有用性~ヘパリンに代わる理想の糖鎖としての治療への応用を検証~
(第10回DSANJ Digital Bio Conference 2022 2022)
現在の再生医療研究に至るまで
(社会の第一線で活躍する若手研究者たち 2022)
Psme3のO-GlcNAc修飾はPボディの形成阻害によりマウス胚性幹細胞の多能性を維持する
(第44回日本分子生物学会年会 2021)
高硫酸化ヒアルロン酸はヘパリンと同程度のFGF1への結合能を有するが血液抗凝固作用を有していない
(第44回日本分子生物学会年会 2021)
放射線腸管障害に対する高硫酸化ヒアルロン酸の治療効果
(第94回日本生化学会大会 2021)

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Education (3)：

Professional career (1)：

Work history (2)：

Awards (2)：

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