Rchr
J-GLOBAL ID：202101007838191175
Update date: May. 16, 2024
Manabe Tatsuya
マナベ タツヤ | Manabe Tatsuya
Affiliation and department：
Research field (4)：
Neuroscience - general
, Neurology
, Immunology
, Neuropathology
Research keywords (12)：
敗血症
, 神経原線維変化
, アミロイドβ
, 敗血症脳症
, マイクログリア
, インフラマソーム
, 細胞老化
, 全身性炎症
, 神経炎症
, 神経変性疾患
, タウ
, アルツハイマー病
Research theme for competitive and other funds (3)：
- 2024 - 2027 アルツハイマー病と慢性腎臓病における血漿中リン酸化タウ上昇の機序の解明
- 2023 - 2024 アルツハイマー病と慢性腎臓病モデルマウスの血漿解析に基づく疾患類似性と連関の探索
- 2022 - 2024 Recapitulation of tau pathology and its relevance with renal failure in mouse models of Alzheimer's disease
Papers (3)：
-
Masanori Hijioka, Tatsuya Manabe, Takashi Saito. Multifactorial glial responses and their contributions to AD continuum. Clinical and Experimental Neuroimmunology. 2023. 14. 2. 82-91
-
Tatsuya Manabe, Michael T. Heneka. Cerebral dysfunctions caused by sepsis during ageing. Nature Reviews Immunology. 2022. 22. 7. 444-458
-
Tatsuya Manabe, Ildikó Rácz, Stephanie Schwartz, Linda Oberle, Francesco Santarelli, Julius V. Emmrich, Jonas J. Neher, Michael T. Heneka. Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing. Journal of Neurochemistry. 2021. 159. 3. 525-542
MISC (1)：
-
Tatsuya Manabe, Ildikó Rácz, Stephanie Schwartz, Francesco Santarelli, Julius V. Emmrich, Jonas J. Neher, Michael T. Heneka. CA3 excitatory synapse loss as a chronic effect of septic shock in middle-aged mice. Alzheimer's & Dementia. 2022. 17. e052228
Books (2)：
-
医学のあゆみ:アルツハイマー病 -研究と治療の最前線
医歯薬出版 2023
-
実験医学増刊:いま新薬で加速する神経変性疾患研究 ー 異常タンパク質の構造、凝集のしくみから根本治療の真の標的に迫る
羊土社 2023 ISBN:9784758104128
Lectures and oral presentations (10)：
-
Systemic inflammation challenging the ageing brains
(The 128th Annual Meeting of the Japanese Association of Anatomists 2023)
-
Study of systemic inflammation and its potential effect on glial senescence during ageing
(The 26th Annual Meeting of the Japan Glia 2022)
-
タウ性状に対する腸内細菌の影響-野生型マウスでの解析-
(第41回認知症学会学術集会 2022)
-
Reversibility of tau hyperphosphorylation in response to hypothermia
(2022)
-
全身性炎症後に起こる認知機能低下の機構とミクログリアの関与
(第24回 IBSセミナー 2022)
ｍore...
Education (3)：
- 2017 - 2021 University of Bonn Faculty of Medicine
- 2016 - 2017 University College London UCL Queen Square Institute of Neurology
- 2014 - 2016 King's College London Faculty of Life Sciences and Medicine
Professional career (3)：
- PhD in Experimental Medicine (University of Bonn)
- MSc in Dementia (UCL)
- BSc in Neuroscience (King's College London)
Work history (2)：
- 2021/10 - 現在 名古屋市立大学 大学院医学研究科 脳神経科学研究所 認知症科学分野 特任助教
- 2017/11 - 2021/07 University of Bonn Medical Center Department of Neurodegenerative Diseases and Geriatric Psychiatry Research assistant
Association Membership(s) (2)：
日本認知症学会
, The Japan Neuroscience Society
