Rchr
J-GLOBAL ID：202101008552134952
Update date: Dec. 02, 2024
HAYASHI YASUTAKA
ハヤシ ヤスタカ | HAYASHI YASUTAKA
Affiliation and department：
Research field (3)：
Cell biology
, Cell biology
, Hematology and oncology
Research keywords (3)：
間葉系幹細胞
, 骨髄微小環境
, 造血幹細胞
Research theme for competitive and other funds (2)：
- 2021 - 2024 間葉系幹細胞の分化異常が引き起こす造血不全の病態解析
- 2020 - 2023 造血器腫瘍における細胞外小胞の動態解析と治療応用
Papers (19)：
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Emi Sugimoto, Jingmei Li, Yasutaka Hayashi, Kohei Iida, Shuhei Asada, Tsuyoshi Fukushima, Moe Tamura, Shiori Shikata, Wenyu Zhang, Keita Yamamoto, et al. Hyperactive Natural Killer cells in Rag2 knockout mice inhibit the development of acute myeloid leukemia. Communications biology. 2023. 6. 1. 1294-1294
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Muran Xiao, Shinji Kondo, Masaki Nomura, Shinichiro Kato, Koutarou Nishimura, Weijia Zang, Yifan Zhang, Tomohiro Akashi, Aaron Viny, Tsukasa Shigehiro, et al. BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state. Nature communications. 2023. 14. 1. 8372-8372
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Atsushi Tanaka, Koutarou Nishimura, Wataru Saika, Ayana Kon, Yui Koike, Hiromi Tatsumi, June Takeda, Masaki Nomura, Weijia Zang, Manabu Nakayama, et al. SETBP1 is dispensable for normal and malignant hematopoiesis. Leukemia. 2023
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Yasutaka Hayashi, Koutarou Nishimura, Atsushi Tanaka, Daichi Inoue. Extracellular vesicle-mediated remodeling of the bone marrow microenvironment in myeloid malignancies. International journal of hematology. 2023
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Atsushi Tanaka, Taizo A Nakano, Masaki Nomura, Hiromi Yamazaki, Jan Philipp Bewersdorf, Roger Mulet-Lazaro, Simon Hogg, Bo Liu, Alex Vincent Penson, Akihiko Yokoyama, et al. Aberrant EVI1 splicing contributes to EVI1-rearranged leukemia. Blood. 2022. 140. 8. 875-888
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MISC (7)：
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林 康貴, 西村 耕太郎, 井上 大地. MDS由来エキソソームを介した骨髄ニッチ改変機構-Bone marrow niche remodeling mediated by EVs from MDS cells. 血液内科 = Hematology / 血液内科編集委員会 編. 2023. 87. 2. 205-210
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Yasutaka Hayashi, Kimihito Cojin Kawabata, Yosuke Tanaka, Yasufumi Uehara, Shigeru Kiryu, Yasunori Ota, Yusuke Yoshioka, Yo Mabuchi, Tatsuki Sugiyama, Keiko Mikami, et al. Impaired Osteoblastic Differentiation of MSCs Suppresses Normal Hematopoiesis in MDS. BLOOD. 2020. 136
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Daichi Inoue, Stanley C Lee, Akihide Yoshimi, Justin Taylor, Lillian E Bitner, Atsushi Tanaka, Yasutaka Hayashi, Hana Cho, Chie Fukui, Ruth Saganty, et al. Aberrant RNA Splicing Contributes to the Pathogenesis of EVI-Rearranged Myeloid Leukemias. Blood. 2019. 134. Supplement_1. 917-917
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Susumu Goyama, Shiori Shikata, Yasutaka Hayashi, Yuto Izawa, Janet Schibler, Hiroyuki Iwamura, Motoki Saito, Satoshi Kofuji, Kazutaka Sumita, Atsuo T. Sasaki, et al. Inhibition of Impdh As an Effective Treatment for MLL-Fusion Leukemia. BLOOD. 2016. 128. 22
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Kimihito Cojin Kawabata, Yasutaka Hayashi, Daichi Inoue, Hiroki Mizuno, Jiro Kitaura, Yosuke Tanaka, Susumu Goyama, Yuka Harada, Hironori Harada, Hiroyuki Aburatani, et al. HIGHER EXPRESSION OF ATP-BINDING CASSETTE TRANSPORTER G2 (ABCG2) IS SPECIFIC TO ADVANCED MDS AND PROMOTES INEFFICIENT HEMATOPIESIS VIA CONVERSIONS OF TUMOR MICROENVIRONMENTS IN MOUSE BONE MARROW TRANSPLANTATION MODEL. EXPERIMENTAL HEMATOLOGY. 2016. 44. 9. S110-S110
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Education (2)：
- 2014 - 2018 The University of Tokyo Graduate School of Medicine
- 2008 - 2014 Kyushu University School of Medicine
Work history (5)：
- 2024/04 - 現在 Tokyo Medical and Dental University Department of Computational and Systems Biology, Medical Research Institute
- 2023/04 - 2024/03 公益財団法人 神戸医療産業都市推進機構 先端医療研究センター 血液・腫瘍研究部 研究員
- 2020/04 - 2023/03 公益財団法人 神戸医療産業都市推進機構 先端医療研究センター 血液・腫瘍研究部 日本学術振興会特別研究員
- 2019/05 - 2020/03 公益財団法人 神戸医療産業都市推進機構 先端医療研究センター 血液・腫瘍研究部 研究員
- 2018/04 - 2019/05 The University of Tokyo The Institute of Medical Science The Advanced Clinical Research Center Division of Cellular Therapy
Association Membership(s) (4)：
日本細胞外小胞学会
, 日本免疫学会
, 日本血液学会
, 日本分子生物学会
