Rchr
J-GLOBAL ID：202101009748284070
Update date: Feb. 01, 2024
Itakura Masanori
イタクラ マサノリ | Itakura Masanori
Affiliation and department：
Job title：
Postdoctoral Researcher
Research theme for competitive and other funds (5)：
- 2023 - 2027 食による自然免疫記憶:タンパク質修飾を介した食品成分の新規機能性発現機構の解明
- 2020 - 2023 核外ヒストンを標的とした食品成分の活性発現機構の解明
- 2018 - 2020 Microglia-neuron interaction in stress response and its regulation by food components
- 2017 - 2019 ミクログリアを基軸とした新規うつ病発症機序の解明と食品成分による予防法の構築
- 2015 - 2017 GAPDH凝集阻害を標的とした新規難治性脳疾患治療薬の創製
Papers (18)：
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Masanori Itakura, Takeya Kubo, Akihiro Kaneshige, Hidemitsu Nakajima. Glyceraldehyde-3-phosphate dehydrogenase regulates activation of c-Jun N-terminal kinase under oxidative stress. Biochemical and Biophysical Research Communications. 2023
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Kosuke Yamaguchi, Masanori Itakura, Mona Tsukamoto, Sei-Young Lim, Koji Uchida. Natural polyphenols convert proteins into histone-binding ligands. Journal of Biological Chemistry. 2022
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Masanori Itakura, Kosuke Yamaguchi, Roma Kitazawa, Sei-Young Lim, Yusuke Anan, Jun Yoshitake, Takahiro Shibata, Lumi Negishi, Hikari Sugawa, Ryoji Nagai, et al. Histone functions as a cell-surface receptor for AGEs. Nature communications. 2022. 13. 1. 2974-2974
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Sei-Young Lim, Kosuke Yamaguchi, Masanori Itakura, Miho Chikazawa, Tomonari Matsuda, Koji Uchida. Unique B-1 cells specific for both N-pyrrolated proteins and DNA evolve with apolipoprotein E deficiency. The Journal of biological chemistry. 2022. 298. 2. 101582-101582
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Kosuke Yamaguchi, Masanori Itakura, Roma Kitazawa, Sei-Young Lim, Koji Nagata, Takahiro Shibata, Mitsugu Akagawa, Koji Uchida. Oxidative deamination of lysine residues by polyphenols generates an equilibrium of aldehyde and 2-piperidinol products. The Journal of biological chemistry. 2021. 297. 3. 101035-101035
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MISC (42)：
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LIM SeiYoung, 山口公輔, 板倉正典, 近澤未歩, 松田知成, 内田浩二. The role of pyrrolated protein in shaping multi-specific IgM-BCR repertoire in apoE deficient mice. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
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板倉 正典, 内田 浩二. 医食同源:食と自然治癒力 抗酸化性食品成分によるタンパク質自然修飾とヒストンを介した生体応答. 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [3S07m-02]
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板倉 正典, 内田 浩二. 限定エクスポソームの新たな展開 抗酸化性食品成分によるタンパク質自然修飾を介した生体恒常性維持機. The Journal of Toxicological Sciences. 2021. 46. Suppl. S57-S58
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LIM SeiYoung, 近澤未歩, 板倉正典, 佐々木栄太, 松田知成, 内田浩二. Mechanism underlying anti-DNA autoantibody production mediated by pyrrolated protein in apoE-deficient mice. 日本農芸化学会大会講演要旨集(Web). 2021. 2021
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林世映, 近澤未歩, 板倉正典, 松田知成, 内田浩二. ApoE欠損マウスにおける抗ピロール化タンパク質抗体レパトアの同定. 日本生化学会大会(Web). 2021. 94th
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Education (2)：
- 2013 - 2017 Osaka Prefecture University Graduate School of Life and Environmental Sciences Division of Veterinary Sciences
- 2007 - 2013 Osaka Prefecture University School of Life and Environmental Sciences Department of Veterinary Sciences
Professional career (1)：
Work history (4)：
- 2023/09 - 現在 University of Luxembourg Luxembourg Centre for Sysetems Biomedicine (LCSB) Postdoctoral Researcher - Neuroinflammation Group
- 2019/11 - 2023/08 The University of Tokyo Graduate School of Agricultural and Life Sciences
- 2017/04 - 2019/10 The University of Tokyo Graduate School of Agricultural and Life Sciences
- 2015/04 - 2017/03 Japan Society for the Promotion of Science
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