Rchr
J-GLOBAL ID：202101009832332543
Update date: Sep. 18, 2024
Sawai (Esaki) Madoka
Sawai (Esaki) Madoka
Affiliation and department：
Research keywords (2)：
シグナル伝達
, TLR4
Research theme for competitive and other funds (1)：
- 2023 - 2025 糖化産物DHPによるTLR4シグナル抑制機構の解明:敗血症治療への新規アプローチ
Papers (8)：
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Jian-Rong Zhou, Shigenori Kinno, Kenta Kaihara, Madoka Sawai, Takumi Ishida, Shinji Takechi, Jun Fang, Toshihiro Nohara, Kazumi Yokomizo. Saponin Esculeoside A and Aglycon Esculeogenin A from Ripe Tomatoes Inhibit Dendritic Cell Function by Attenuation of Toll-like Receptor 4 Signaling. Nutrients. 2024. 16. 11. 1699-1699
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Shinji Takechi, Madoka Sawai, Yuu Miyauchi. Dihydropyrazine induces endoplasmic reticulum stress and inhibits autophagy in HepG2 human hepatoma cells. The Journal of Toxicological Sciences. 2024. 49. 7. 313-319
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Yuu Miyauchi, Haruna Koba, Madoka Sawai, Hisao Kansui, Shinji Takechi. Oxidative stress and cellular toxicity induced by dihydropyrazine: a comparative study with other Maillard reaction products. The Journal of toxicological sciences. 2023. 48. 5. 263-272
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Madoka Sawai, Yuu Miyauchi, Takumi Ishida, Shinji Takechi. Dihydropyrazine suppresses TLR4-dependent inflammatory responses by blocking MAPK signaling in human hepatoma HepG2 cells. The Journal of Toxicological Sciences. 2022. 47. 9. 381-387
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Yuu Miyauchi, Akane Kimura, Madoka Sawai, Keiko Fujimoto, Yuko Hirota, Yoshitaka Tanaka, Shinji Takechi, Peter I. Mackenzie, Yuji Ishii. Use of a Baculovirus-Mammalian Cell Expression-System for Expression of Drug-Metabolizing Enzymes: Optimization of Infection With a Focus on Cytochrome P450 3A4. Frontiers in Pharmacology. 2022. 13
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Lectures and oral presentations (31)：
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Dihydropyrazine application to prevent and treat sepsis: therapeutic effect in multiple organs
(フォーラム2024 衛生薬学・環境トキシコロジー 2024)
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糖化産物ジヒドロピラジンによる炎症抑制効果解析
(日本薬学会第144回年会(横浜)2024/3/30 2024)
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Anti-inflammatory effects of the glycation product dihydropyrazine: An in vivo analysis using mice with contact dermatitis.
(第46回日本分子生物学会年会(神戸)2023/12/7 2023)
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Alleviation effect of Contact Dermatitis by the Glycation Product Dihydropyrazine.
(フォーラム2023衛生薬学・環境トキシコロジ 2023)
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糖化産物dihydropyrazineによる接触性皮膚炎モデルマウス症状緩和のメカニズム解析
(日本薬学学会143年会 2023)
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Association Membership(s) (1)：
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