Rchr
J-GLOBAL ID:202101011504934174
Update date: Jan. 30, 2024
Kawasumi Ryotaro
カワスミ リョウタロウ | Kawasumi Ryotaro
Affiliation and department:
Research field (2):
Molecular biology
, Molecular biology
Research keywords (8):
Genetics
, Nucleoside analogue
, Chromosome
, Sister chromatid cohesion
, Synthetic lethal
, DNA repair
, Replication
, Cohesin
Research theme for competitive and other funds (1):
- 2022 - 2024 18-1-8 complex as a therapeutic target?
Papers (9):
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Tasnim Ahmad, Ryotaro Kawasumi, Tomoya Taniguchi, Takuya Abe, Kazuhiro Terada, Masataka Tsuda, Naoto Shimizu, Toshiki Tsurimoto, Shunichi Takeda, Kouji Hirota. The proofreading exonuclease of leading-strand DNA polymerase epsilon prevents replication fork collapse at broken template strands. Nucleic Acids Research. 2023
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Ivan Psakhye, Ryotaro Kawasumi, Takuya Abe, Kouji Hirota, Dana Branzei. PCNA recruits cohesin loader Scc2 to ensure sister chromatid cohesion. Nature structural & molecular biology. 2023
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Mubasshir Washif, Tasnim Ahmad, Md Bayejid Hosen, Md Ratul Rahman, Tomoya Taniguchi, Hiromori Okubo, Kouji Hirota, Ryotaro Kawasumi. CTF18-RFC contributes to cellular tolerance against chain-terminating nucleoside analogs (CTNAs) in cooperation with proofreading exonuclease activity of DNA polymerase ε. DNA repair. 2023. 127. 103503-103503
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Ryotaro Kawasumi, Takuya Abe, Ivan Psakhye, Keiji Miyata, Kouji Hirota, Dana Branzei. Vertebrate CTF18 and DDX11 essential function in cohesion is bypassed by preventing WAPL-mediated cohesin release. Genes & Development. 2021. 35. 19-20. 1368-1382
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Francesco Rossi, Anne Helbling-Leclerc, Ryotaro Kawasumi, Nanda Kumar Jegadesan, Xinlin Xu, Pierre Devulder, Takuya Abe, Minoru Takata, Dongyi Xu, Filippo Rosselli, et al. SMC5/6 acts jointly with Fanconi anemia factors to support DNA repair and genome stability. EMBO reports. 2020. 21. 2. e48222
more...
Work history (4):
- 2021/10 - 現在 Tokyo Metropolitan University
- 2020/12 - 2021/09 IFOM - the FIRC Institute of Molecular Oncology DNA repair unit PosDoc
- 2016/07 - 2020/11 The Open University, School of Life, Health and Chemical Sciences PhD student
- 2014/04 - 2016/03 Department of Chemistry, Graduate School of Science and Engineering, Tokyo Metropolitan University Master student
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