Rchr
J-GLOBAL ID:202101012702854271
Update date: Jan. 05, 2025
Maruyama Keiko
マルヤマ ケイコ | Maruyama Keiko
Affiliation and department:
Research field (1):
Hematology and oncology
Research keywords (1):
血液凝固
Research theme for competitive and other funds (8):
- 2023 - 2026 凝固第V因子改変体を用いた新たなプロテインSおよびプロテインC活性検査法の確立
- 2023 - 2024 Pros1イントロン1欠失マウスを用いたプロテインS発現調節機構の解明
- 2022 - 2023 Protein S遺伝子のイントロン1に潜む未知の発現調節機構の解明
- 2020 - 2023 血液凝固制御因子プロテインSおよびプロテインCの活性測定法の開発
- 2022 - 血栓形成抑制に重要な働きをするプロテインSの新たな発現調節機構の解明
- 2017 - 2020 赤血球の変化と鉄欠乏が循環器疾患に与える影響の解析
- 2016 - 2019 Studies on thrombotic risk of protein S K196E mutation
- 2013 - 2015 Production and analysis of Bac-TRAP mice that express fluorescent proteins driven by thrombomodulin or endothelial cell protein C receptor promoter
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Papers (15):
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Keiko Maruyama, Koichi Kokame. Development of an assay using a modified coagulation factor V to measure protein S activity. Journal of Thrombosis and Haemostasis. 2024. 22. 12. 3510-3520
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Naruto Shimonishi, Eriko Morishita, Kenichi Ogiwara, Keiko Maruyama, Junko Yoshida, Kyoji Horie, Keiji Nogami. A novel factor V compound heterozygous mutation associated with thrombosis (Y1961C; FV-Kanazawa, together with 1982_1983del). Journal of Thrombosis and Haemostasis. 2024. 22. 10. 2810-2822
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Keiko Maruyama, Shigeki Miyata, Koichi Kokame. Alpha-HIT assay: A new assay for heparin-induced thrombocytopenia antibody detection using FcγRIIa-coated beads and Alpha technology. Research and Practice in Thrombosis and Haemostasis. 2022. 6. 7
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Satomi Nagaya, Keiko Maruyama, Atsushi Watanabe, Makiko Meguro-Horike, Yuta Imai, Yuki Hiroshima, Shin-Ichi Horike, Koichi Kokame, Eriko Morishita. First report of inherited protein S deficiency caused by paternal PROS1 mosaicism. Haematologica. 2021. 107. 1. 330-333
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Makoto Osada, Keiko Maruyama, Koichi Kokame, Ryunosuke Denda, Kohei Yamazaki, Hisako Kunieda, Maki Hirao, Seiji Madoiwa, Nobuo Okumura, Mitsuru Murata, et al. A novel homozygous variant of the thrombomodulin gene causes a hereditary bleeding disorder. Blood Advances. 2021
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MISC (3):
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Keiko MARUYAMA, Koichi KOKAME. Estimating the frequencies of pathogenic variants of antithrombin, protein C, and protein S using a public database and expression experiments. Japanese Journal of Thrombosis and Hemostasis. 2021. 32. 5. 635-637
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Keiko MARUYAMA. ELISA-based detection system for Protein S K196E mutation, a genetic risk factor for venous thromboembolism. Japanese Journal of Thrombosis and Hemostasis. 2016. 27. 4. 466-470
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宮田敏行, 丸山慶子. 日本人における先天性血栓性素因-欧米との比較-. 臨床血液. 2014. 55. 8. 908-916
Books (3):
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臨床に直結する血栓止血学 改訂2版
中外医学社 2018 ISBN:9784498125797
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動脈・静脈の疾患(上)
日本臨牀社 2017
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止血・血栓ハンドブック
西村書店 2015
Education (3):
- 2010 - 2013 金沢大学大学院 医学系研究科 博士後期課程(保健学専攻)
- 2008 - 2010 Kanazawa University
- 2004 - 2008 Kanazawa University
Work history (5):
- 2023/12 - 現在 国立研究開発法人国立循環器病研究センター 研究所 分子病態部 上級研究員
- 2020/04 - 2023/11 National Cerebral and Cardiovascular Center, Research Institute Department of Molecular Pathogenesis
- 2017/04 - 2020/03 National Cerebral and Cardiovascular Center, Research Institute Department of Molecular Pathogenesis
- 2016/04 - 2017/03 National Cerebral and Cardiovascular Center, Research Institute Department of Molecular Pathogenesis
- 2013/04 - 2016/03 National Cerebral and Cardiovascular Center, Research Institute Department of Molecular Pathogenesis
Awards (3):
- 2024 - The 32nd Congress of the International Society on Thrombosis and Haemostasis, Top Poster Award
- 2022/06 - 日本血栓止血学会 第44回日本血栓止血学会学術集会 優秀ポスター賞
- 2016/06 - 日本血栓止血学会 第21回日本血栓止血学会学術奨励賞
Association Membership(s) (3):
日本検査血液学会
, 日本血液学会
, 日本血栓止血学会
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