Aoki-Saito Haruka

サイトウ (アオキ) ハルカ | Aoki-Saito Haruka

Affiliation and department：
Job title： medical staff

Research field (1)： Respiratory medicine

Research keywords (3)： bronchial asthma , airway inflammation , inflammation

Research theme for competitive and other funds (6)：

2018 - 2023 気道炎症におけるプロトン感知性受容体OGR1を介した新規吸入薬開発への挑戦
2016 - 2019 The finding of glucose metabolism improver derived from skeletal muscle
2015 - 2018 Action mechanism of pH-sensing OGR1 family receptors and in vivo functions
2015 - 2018 Research for anti-inflammatory therapeutic strategy against pulmonary fibrosis
2015 - 2017 The role of proton-sensing ovarian cancer G protein-coupled receptor 1 on dendritic cells and T cells in a murine asthma model

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Papers (134)：

Mari Sato, Masakiyo Yatomi, Ikuo Wakamatsu, Shogo Uno, Chiharu Hanazato, Tomomi Masuda, Koichi Yamaguchi, Haruka Aoki-Saito, Norimitsu Kasahara, Yosuke Miura, et al. Effective treatment with mepolizumab in a patient with severe eosinophilic granulomatosis with polyangiitis complicated with small intestine perforation. Respiratory medicine case reports. 2023. 43. 101818-101818
Shota Arai, Koichi Fujiwara, Masahiro Kojima, Haruka Aoki-Saito, Masakiyo Yatomi, Tsugumichi Saito, Yasuhiko Koga, Hayato Fukuda, Mizuki Watanabe, Shigeki Matsunaga, et al. Design and Synthesis of Cyclopropane Congeners of Resolvin E3, an Endogenous Pro-Resolving Lipid Mediator, as Its Stable Equivalents. The Journal of Organic Chemistry. 2022. 87. 15. 10501-10508
Yoshimasa Hachisu, Yasuhiko Koga, Shu Kasama, Kyoichi Kaira, Shogo Uno, Masakiyo Yatomi, Haruka Aoki-Saito, Hiroaki Tsurumaki, Asuka Jingu, Noriaki Sunaga, et al. The Relationship between Tumor Development and Sarcoidosis in Aspects of Carcinogenesis before and after the Onset of Sarcoidosis. Medicina (Kaunas, Lithuania). 2022. 58. 6
Mio Kanbe, Masakiyo Yatomi, Ikuo Wakamatsu, Shogo Uno, Chiharu Hanazato, Haruka Aoki-Saito, Tomomi Masuda, Koichi Yamaguchi, Norimitsu Kasahara, Yosuke Miura, et al. A pregnant woman with severe dyspnoea. Breathe (Sheffield, England). 2022. 18. 2. 220012-220012
Koichi Yamaguchi, Takahito Nakajima, Aya Yamaguchi, Miki Itai, Yuji Onuki, Yuki Shin, Shogo Uno, Sohei Muto, Shunichi Kouno, Masakiyo Yatomi, et al. Quantitative CT analysis of interstitial pneumonia in anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis: a single center, retrospective study. Clinical rheumatology. 2022. 41. 5. 1473-1481

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MISC (10)：

佐藤真季子, 青木悠, 鶴巻寛朗, 矢冨正清, 古賀康彦, 砂長則明, 石塚全, 土橋邦生, 周東智, 前野敏孝, et al. ResolvinE1、E2、E3のアレルギー性気道炎症に対する効果の検討. 日本呼吸器学会誌. 2022. 11. 増刊. 282-282
門脇麻衣子, 山田秀典, 佐藤幸市, 重見博子, 梅田幸寛, 森川美羽, 早稲田優子, 安斎正樹, 上出庸介, 青木悠, et al. 細胞外酸性刺激によるヒト気道平滑筋細胞のCXCL8産生におけるNF-κBの関与とステロイド反応性. アレルギー. 2019. 68. 4-5. 571-571
サイトウ(アオキ) ハルカ, ヒサダタケシ. レゾルビンとアレルギー. 2018. 25. 3. 388-397
古賀康彦, 佐藤隆博, 解良恭一, 江夏昌志, 蜂巣克昌, 久田剛志, 矢冨正清, 小野昭浩, 清水泰生, 青木悠, et al. 特発性肺線維症患者における予後予測因子としての肺内吸入元素の検討. 日本職業・環境アレルギー学会雑誌. 2016. 24. 1. 60-60
古賀康彦, 矢冨正清, 上出庸介, 関香織, 鶴巻寛朗, 青木悠, 解良恭一, 小野昭浩, 砂長則明, 久田剛志, et al. p116Rip proteinの気道培養細胞での炎症性サイトカイン分泌に及ぼす影響について. アレルギー. 2014. 63. 3-4. 573-573

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Lectures and oral presentations (18)：

Analysis of anti-inflammatory effects of Resolvin E3 and its deoxy derivatives
(APSR 2021)
Analysis of anti-inflammatory effects of Resolvin E3 derivatives on dendritic cells
(2021)
最近のアレルギーの知見~各科女性医師・若手医師の活躍(シンポジウム) 内科の立場から「Resolvin E3 (RvE3)のマウス気管支喘息モデルにおける効果に対する解析」
(第3回アレルギー学会関東地方会 2020)
Resolvin E3 dampens asthmatic inflammation in a murine model through IL-23 pathway
(European Respiratory Society International Congress 2019 2019)
OGR1欠損マウスを用いたHDM気管支喘息モデルの解析
(第66回日本アレルギー学会学術大会 2017)

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Education (2)：

2007 - 2012 Gunma University Graduate School of Medicine Allergy and Respiratory Medicine
1997 - 2003 Gunma University Faculty of Medicine School of Medicine

Work history (8)：

2022/05 - 現在群馬大学医学部附属病院呼吸器・アレルギー内科助教(危機対応)
2016/04 - 2022/04 Gunma University University Hospital Regional Medical Research and Education Center
2013/08 - 2016/03 Gunma University Institute for Molecular and Cellular Regulation
2012/04 - 2013/07 Gunma University Institute for Molecular and Cellular Regulation
2006/04 - 2007/03 Gunma University University Hospital Allergy and Respiratory Medicine

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Awards (2)：

2009 - European Respiratory Society Young Sciensist Sponsorship 「Resolvin E1 Dampens Airway Inflammation and Hyperresponsiveness in a Murine Model of Asthma」
2008 - 日本アレルギー学会第5回日本アレルギー学会学術大会賞「新規抗炎症脂質メディエーターResolvinE1のTh2系疾患モデルへの作用」

Association Membership(s) (5)：

日本職業・環境アレルギー学会 , 日本感染症学会 , 日本アレルギー学会 , 日本呼吸器内科学会 , 日本内科学会

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