Shibata Yuki

シバタユウキ | Shibata Yuki

Affiliation and department：

Research field (1)： Developmental biology

Research keywords (7)：両生類 , トランスジェネシス , Thyroid hormone receptor , Thyroid hormone , Regeneration , Metamorphosis , Genome editing

Research theme for competitive and other funds (4)：

2023 - 2026 空間トランスクリプトームによる消化管上皮幹細胞形成に関わる遺伝子の探索と機能解析
2021 - 2023 Cas13dを用いた両生類の四肢発生に関わる遺伝子の時期特異的ノックダウン
2017 - 2019 Investigating the function of the histone methyltransferase PRMT1 during thyroid hormone dependent metamorphosis and adult intestinal stem cell development in Xenopus tropicalis
2013 - 2015 両生類におけるアクアポリンの生理学的役割、遺伝子発現調節機構、および進化プロセス

Papers (30)：

Miyuki Suzuki, Akinori Okumura, Akane Chihara, Yuki Shibata, Tetsuya Endo, Machiko Teramoto, Kiyokazu Agata, Marianne E. Bronner, Ken-ichi T. Suzuki. Fgf10 mutant newts regenerate normal hindlimbs despite severe developmental defects. Proceedings of the National Academy of Sciences. 2024. 121. 11
Masatoshi Hibino, Ryota Aoki, Duy Anh Ha, Haruna Sano, Shiori Yamashita, Haruto Ogasawara, Kazuma Nishio, Kohei Kotake, Md. Main Uddin Mamun, Reiko Okada, et al. Ontogenetic Expression of Aquaporins in the Kidney and Urinary Bladder of the Japanese Tree Frog, Dryophytes japonicus. Zoological Science. 2024. 41. 1
Liezhen Fu, Shouhong Wang, Lusha Liu, Yuki Shibata, Morihiro Okada, Nga Luu, Yun-Bo Shi. Simplifying Genotyping of Mutants from Genome Editing with a Parallel qPCR-Based iGenotype Index. Cells. 2024
Yuki Shibata, Akinori Okumura, Makoto Mochii, Ken-ichi T. Suzuki. Protocols for transgenesis at a safe harbor site in the Xenopus laevis genome using CRISPR-Cas9. STAR Protocols. 2023. 4. 3. 102382-102382
Kenta Fujimoto, Yuki Shibata, Takashi Hasebe. Thyroid Hormone-Activated Signaling Pathways are Essential for Development of Intestinal Stem Cells. Journal of Nippon Medical School. 2023. 90. 3. 246-252

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MISC (7)：

ゲノム編集による高効率遺伝子導入ツメガエル作出法の開発 ~両生類の再生能力の謎に迫るための新技術~. プレスリリース. 2022
柴田侑毅. 無尾両生類の変態過程における甲状腺ホルモン受容体の役割. 比較内分泌学. 2021. 47. 173. 57-60
Molecular function of thyroid hormone receptor during frog development. Comparative Endocrinology. 2019. 45. 166. 42-42
Yuki Shibata, Yun-Bo Shi. Investigating the function of the histone methyltransferase PRMT1 during post-embryonic development in Xenopus tropicalis. The FASEB Journal. 2018. 32. S1
Stanley Hillyard, Yuki Shibata, Takatoshi Nagai, Masakazu Suzuki. Anuran-like Aquaporins in the Skin and Urinary Bladder of a Urodele, Evidence for Early Gene Duplication in the Lissamphibia. The FASEB Journal. 2015. 29. S1

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Books (1)：

Lectures and oral presentations (37)：

NEXTrans: Simple transgenesis at a novel safe harbor site by using CRISPR-Cas9 in Xenopus laevis
(19th International Xenopus Conference 2023)
Genetic analysis of thyroid hormone regulation of intestinal remodeling in Xenopus
(7th Biennial Meeting of The North American Society for Comparative Endocrinology 2023)
アフリカツメガエルの新たなトランスジェニック動物作製法〜NEXTrans (New and Easy Xenopus Transgenesis at a safe harbor site)〜
(第93回日本動物学会シンポジウムS12「新規モデル生物で遺伝子ノックイン技術を駆使する研究の醍醐味〜先人の試行錯誤から成功の秘訣を学ぶ」 2022)
ネッタイツメガエル(Xenopus tropicalis)における AQP6/a2S の発現制御に関する分子生物学的研究
(第45回日本比較内分泌学会 2021)
CRISPR/Cas9を用いた新規トランスジェニックカエル作製法の開発
(第45回日本比較内分泌学会 2021)

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Education (3)：

2012 - 2015 静岡大学創造科学技術大学院自然科学系教育部バイオサイエンス
2010 - 2012 Shizuoka University Graduate School of Science
2006 - 2010 Shizuoka University Faculty of Science Department of Biological Science

Work history (6)：

2022/08 - 現在 Nippon Medical School
2021/04 - 2022/08 National Institute for Basic Biology
2015/07 - 2021/03 National Institutes of Health (NIH) Eunice Kennedy Shriver National Institute Child Health and Human Development (NICHD) Visiting fellow
2017/03 - 2019/02 National Institute of Health (NIH) NICHD JSPS 海外特別研究員NIH (海特NIH)
2015/04 - 2015/06 Shizuoka University Faculty of Science Department of Biological Science

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Committee career (1)：

Awards (8)：

2021/12 - NIBB若手研究者賞
2021/10 - Cell and Bioscience (BMC) Ming K. Jeang Award for Excellence in Cell & Bioscience: Thyroid hormone receptor beta is critical for intestinal remodeling during Xenopus tropicalis metamorphosis:
2020 - National Institute of Health (NIH) Fellows Award for Research Excellence (FARE)
2019/05 - North American Society for Comparative Endocrinology (NASCE) NASCE Student Hotel Award
2018 - American Thyroid Association Trainee Grant Program (Travel award)

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Association Membership(s) (3)：

American Thyroid Association , Japan Society of Comparative Endocrinology , The Zoological Society of Japan

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