Rchr
J-GLOBAL ID：202101014326484029
Update date: Sep. 13, 2024
Yamaguchi Yoko
ヤマグチ ヨウコ | Yamaguchi Yoko
Affiliation and department：
Job title：
Assistant Professor
Research field (2)：
Tumor biology
, Nutrition and health science
Research theme for competitive and other funds (6)：
- 2024 - 2025 Function of p53/c-myc pathway in senescence and oncogenesis
- 2022 - 2023 Molecular mechanisms of the p53/c-myc pathway in the oncogenic process using organoids
- 2018 - 2019 Analysis of molecular mechanisms of decreased apoptotic cell removal by macrophage in aged mice
- 2015 - 2018 Functional analysis of tumor suppressor PHLDA3 -towards understanding carcinogenesis of neuroendocrine tumors-
- 2015 - 2017 Functional analysis of the tumor suppressor gene PHLDA3 to develop personalized medicines for neuroendocrine tumors, a rare cancer.
- 2014 - 2015 Functional analysis of the tumor suppressor gene PHLDA3 to develope personalized medicines for neuroendocrine tumors, a rare cancer
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Papers (10)：
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Nobuhiro Akita, Ryu Okada, Kyosuke Mukae, Ryuichi P. Sugino, Hisanori Takenobu, Koji Chikaraishi, Hidemasa Ochiai, Yohko Yamaguchi, Miki Ohira, Haruhiko Koseki, et al. Polycomb group protein BMI1 protects neuroblastoma cells against DNA damage-induced apoptotic cell death. Experimental cell research. 2023. 422. 1. 113412-113412
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Yohko Yamaguchi, Kohei Kaida, Yusuke Suenaga, Akihito Ishigami, Yoshiro Kobayashi, Kisaburo Nagata. Age-related dysfunction of p53-regulated phagocytic activity in macrophages. Biochemical and Biophysical Research Communications. 2020. 529. 2. 462-466
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Yusuke Suenaga, Mami Yamamoto, Tetsushi Sakuma, Manabu Sasada, Fumio Fukai, Miki Ohira, Yohko Yamaguchi, Takashi Yamamoto, Kiyohiro Ando, Toshinori Ozaki, et al. TAp63 represses transcription of MYCN/NCYM gene and its high levels of expression are associated with favorable outcome in neuroblastoma. Biochemical and Biophysical Research Communications. 2019. 518. 2. 311-318
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Momoko Otaki, Tetsuya Hirano, Yohko Yamaguchi, Kohei Kaida, Seiji Koshika, Kisaburo Nagata, Mayumi Nishimura, Shizuko Kakinuma, Yoshiya Shimada, Yoshiro Kobayashi. Changes in the function and phenotype of resident peritoneal macrophages after housing in an enriched environment. International Immunopharmacology. 2018. 65. 44-49
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Yu Chen, Masahiro Takikawa, Shuichi Tsutsumi, Yoko Yamaguchi, Atsushi Okabe, Mayuna Shimada, Tatsuya Kawase, Akane Sada, Issei Ezawa, Yuhei Takano, et al. PHLDA 1, another PHLDA family protein that inhibits Akt. Cancer Science. 2018. 109. 11. 3532-3542
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MISC (4)：
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大木 理恵子, 山口 陽子. 第I部:がん治療に求められる基盤的知識(1)がんの生物学・分子生物学. がん治療認定医教育セミナーテキスト, 第11版. 2017
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大木 理恵子, 山口 陽子. 第I部:がん治療に求められる基盤的知識(1)がんの生物学・分子生物学. がん治療認定医教育セミナーテキスト, 第10版. 2016
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陳 ヨ, 斉藤 梢, 山口 陽子, 大木 理恵子. Akt抑制遺伝子であるPHLDA3は膵神経内分泌腫瘍の新規癌抑制遺伝子である. 胆と膵. 2015. 36. 6
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山口 陽子, 斉藤 梢, 陳 ヨ, 大木 理恵子. 新規がん抑制遺伝子PHLDA3によるAkt経路の制御機構と治療への展開 -膵神経内分泌腫瘍の個別化医療開発を目指して-. 実験医学. 2014
Education (3)：
- 2010 - 2014 Chiba University Graduate School of Medical and Pharmaceutical Sciences
- 2008 - 2010 Chiba University Graduate School of Medical and Pharmaceutical Sciences
- 2004 - 2008 Toho University Faculty of Science Department of Biomolecular Science
Professional career (1)：
Work history (6)：
Committee career (4)：
- 2021/09 - 現在 Frontiers in Cell and Developmental Biology Review Editor
- 2021/09 - 現在 Frontiers in Oncology Review Editor
- 2017/01 - 2017/12 Japanese Board of Cancer Therapy Education Committee Collaborator
- 2016/01 - 2016/12 Japanese Board of Cancer Therapy Education Committee Collaborator
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