Hosono Yasuyuki

ホソノヤスユキ | Hosono Yasuyuki

Affiliation and department：
Job title： Professor
Research theme for competitive and other funds (10)：

2023 - 2027 Development of a novel therapeutic strategy targeting the microenvironment that tolerates the progression of refractory lung cancer
2022 - 2025 癌・精巣リボヌクレオタンパク質の機能解明と、新規抗がん剤創出
2022 - 2025 Validation and drug development for anti-cancer therapy targeting hemolysis-hemopexin related axis
2022 - 2025 固形癌における抗腫瘍薬の薬剤耐性を改善するグルタミン代謝抑制化合物の開発
2021 - 2024 Development of therapeutic drugs fro achondroplasia-Examination of FGFR3 inhibitory effects of meclizine hydrochloride

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Papers (19)：

Mika Iwai, Taisuke Kajino, Masahiro Nakatochi, Kiyoshi Yanagisawa, Yasuyuki Hosono, Hisanori Isomura, Yukako Shimada, Motoshi Suzuki, Ayumu Taguchi, Takashi Takahashi. Long non-coding RNA TILR constitutively represses TP53 and apoptosis in lung cancer. Oncogene. 2022
Genta Takemoto, Masaki Matsushita, Takaaki Okamoto, Toshinari Ito, Yuki Matsuura, Chieko Takashima, Toyofumi Fengshi Chen-Yoshikawa, Hiromichi Ebi, Shiro Imagama, Hiroshi Kitoh, et al. Meclozine Attenuates the MARK Pathway in Mammalian Chondrocytes and Ameliorates FGF2-Induced Bone Hyperossification in Larval Zebrafish. Frontiers in cell and developmental biology. 2021. 9. 694018-694018
Yingsong Lin, Masahiro Nakatochi, Yasuyuki Hosono, Hidemi Ito, Yoichiro Kamatani, Akihito Inoko, Hiromi Sakamoto, Fumie Kinoshita, Yumiko Kobayashi, Hiroshi Ishii, et al. Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer. Nature communications. 2020. 11. 1. 3175-3175
Carlotta Costa, Ye Wang, Amy Ly, Yasuyuki Hosono, Ellen Murchie, Charlotte S Walmsley, Tiffany Huynh, Christopher Healy, Rachel Peterson, Shogo Yanase, et al. PTEN Loss Mediates Clinical Cross-Resistance to CDK4/6 and PI3Kα Inhibitors in Breast Cancer. Cancer discovery. 2020. 10. 1. 72-85
Yasuyuki Hosono, Toshiki Masuishi, Seiichiro Mitani, Rui Yamaguchi, Seiichi Kato, Takayuki Yoshino, Hiromichi Ebi. Evaluation of ALK Fusion Newly Identified in Colon Cancer by a Comprehensive Genomic Analysis. JCO Precision Oncology. 2019. 3. 1-5

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Education (2)：

2007 - 2011 名古屋大学大学院医学系研究科
1997 - 2003 名古屋大学医学部医学科

Work history (10)：

2021/10 - 現在 Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Department of Pharmacology Professor
2018/04 - 2021/09 愛知県がんセンター研究所・がん標的治療TR分野・ユニット長
2018/02 - 2018/03 愛知県がんセンター研究所・腫瘍病理学部・室長
2013/01 - 2018/01 University of Michigan, Department of Pathology, Postdoctoral Fellow
2011/04 - 2012/12 名古屋大学大学院医学系研究科・博士研究員

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