Rchr
J-GLOBAL ID：202101015670883508
Update date: Aug. 08, 2024
MORIO HANAE
モリオ ハナエ | MORIO HANAE
Affiliation and department：
Research keywords (3)：
ヒト不死化細胞モデル
, がん遺伝子
, トランスポーター
Research theme for competitive and other funds (3)：
- 2024 - 2026 ヒト脳マイクロパソフィジオロジカルシステムズ:脳疾患の生体模倣と創薬研究への応用
- 2022 - 2026 ヒト脳マイクロパソフィジオロジカルシステムズ:脳疾患の生体模倣と創薬研究への応用
- 2021 - 2023 BBTB標的創薬に有用な生体模倣性新規in vitroヒトBBTBモデルの樹立
Papers (16)：
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Ryuto Isogai, Hanae Morio, Ayaka Okamoto, Keita Kitamura, Tomomi Furihata. Generation of a Human Conditionally Immortalized Cell-based Multicellular Spheroidal Blood-Brain Barrier Model for Permeability Evaluation of Macromolecules. Bio-protocol. 2022. 12. 15. e4465
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Ryo Ito, Hanae Morio, Tomoyo Baba, Yasuyuki Sakaguchi, Naomi Wakayama, Ryuto Isogai, Yoshiyuki Yamaura, Takafumi Komori, Tomomi Furihata. In Vitro-In Vivo Correlation of Blood-Brain Barrier Permeability of Drugs: A Feasibility Study Towards Development of Prediction Methods for Brain Drug Concentration in Humans. Pharmaceutical research. 2022. 39. 7. 1575-1586
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Keita Kitamura, Ayaka Okamoto, Hanae Morio, Ryuto Isogai, Ryo Ito, Yoshiyuki Yamaura, Saki Izumi, Takafumi Komori, Shingo Ito, Sumio Ohtsuki, et al. Human Immortalized Cell-Based Blood-Brain Barrier Spheroid Models Offer an Evaluation Tool for the Brain Penetration Properties of Macromolecules. Molecular pharmaceutics. 2022. 19. 8. 2754-2764
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Katharina Woess, Yuchen Sun, Hanae Morio, Anna Stierschneider, Anna Kaufmann, Stefan Hainzl, Lisa Trattner, Thomas Kocher, Birgit Tockner, Victoria Leb-Reichl, et al. Evaluating a Targeted Cancer Therapy Approach Mediated by RNA trans-Splicing In Vitro and in a Xenograft Model for Epidermolysis Bullosa-Associated Skin Cancer. International journal of molecular sciences. 2022. 23. 1
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Hanae Morio, Yoshie Reien, Yuri Hirayama, Hirofumi Hashimoto, Naohiko Anzai. Protein kinase C activation upregulates human L-type amino acid transporter 2 function. The Journal of Physiological Sciences. 2021. 71. 1. 11-11
ｍore...
MISC (2)：
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Meiyan Zhu, Tomomi Furihata, Akira Koibuchi, Hideyuki Ide, Hanae Morio, Minaka Shibuya, Atsuko Kamiichi, Hidetaka Akita, Kan Chiba. A NEW IMMORTALIZED HUMAN LIVER SINUSOIDAL ENDOTHELIAL CELL LINE: ESTABLISHMENT, CHARACTERIZATION, AND APPLICATION POTENTIAL TO DEVELOPMENT OF IN VITRO HUMAN LIVER MODELS. DRUG METABOLISM AND PHARMACOKINETICS. 2017. 32. 1. S70-S70
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Yuki Suzuki, Tomomi Furihata, Zhongguo Fu, Shogo Matsumoto, Akihito Tsubota, Yuchen Sun, Hanae Morio, Kan Chiba. IDENTIFICATION OF SIMEPREVIR AND ASUNAPREVIR AS UNIQUE OATP INHIBITORS WITH LONG-LASTING PROPERTIES. DRUG METABOLISM REVIEWS. 2015. 47. 262-262
Education (2)：
- 2017 - 2021 Chiba University
- 2011 - 2017 Chiba University
Work history (4)：
- 2021/04 - 現在 東京薬科大学 薬学部 医療薬学科 個別化薬物治療学教室 助教
- 2017/04 - 2021/03 千葉大学 医学薬学府 先端医学薬学専攻 薬理学教室
- 2018/10 - 2019/10 EB-Haus Austria The Piñón/Gruber Working Group
- 2011/04 - 2017/03 千葉大学 薬学部 薬物学教室
Awards (6)：
Association Membership(s) (4)：
日本薬理学会
, 日本癌学会
, 日本分子生物学会
, 日本薬物動態学会
