Rchr
J-GLOBAL ID：202101016846647713
Update date: May. 29, 2024
TAKAHASHI SAYAKA
タカハシ サヤカ | TAKAHASHI SAYAKA
Affiliation and department：
Research theme for competitive and other funds (4)：
- 2022 - 2025 腸内環境改善と炎症制御による新たなサルコペニア肥満治療の開発
- 2020 - 2023 脂肪炎症とディスバイオシスの相互修飾による認知症発症機構解明と治療への応用
- 2018 - 2021 Elucidation and application to treatment of the mechanism of intestinal regeneration dysfunction cased by high-fat diet intake and psychological stress ical stress and its application to treatment
- 2017 - 2020 Clarification and prevention of novel mechanisms of cognitive impairment in patients with metabolic syndrome
Papers (10)：
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Sayaka Takahashi, Keiichi Nakagawa, Wataru Nagata, Akiho Koizumi, Toshiaki Ishizuka. A preliminary therapeutic study of the effects of molecular hydrogen on intestinal dysbiosis and small intestinal injury in high-fat diet-loaded senescence-accelerated mice. Nutrition (Burbank, Los Angeles County, Calif.). 2024. 122. 112372-112372
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Wataru Nagata, Akiho Koizumi, Keiichi Nakagawa, Sayaka Takahashi, Mari Gotoh, Yasushi Satoh, Toshiaki Ishizuka. Treatment with lysophosphatidic acid prevents microglial activation and depression-like behaviours in a murine model of neuropsychiatric systemic lupus erythematosus. Clinical and experimental immunology. 2023. 212. 2. 81-92
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Toshiaki Ishizuka, Wataru Nagata, Sayaka Nomura-Takahashi, Yasushi Satoh. Effects of oxidized low-density lipoprotein on differentiation of mouse neural progenitor cells into neural cells. European journal of pharmacology. 2020. 888. 173456-173456
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Hiroko Yamashita, Shusuke Tomoshige, Sayaka Nomura, Kenji Ohgane, Yuichi Hashimoto, Minoru Ishikawa. Application of protein knockdown strategy targeting β-sheet structure to multiple disease-associated polyglutamine proteins. Bioorganic & medicinal chemistry. 2020. 28. 1. 115175-115175
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Shusuke Tomoshige, Sayaka Nomura, Kenji Ohgane, Yuichi Hashimoto, Minoru Ishikawa. Degradation of huntingtin mediated by a hybrid molecule composed of IAP antagonist linked to phenyldiazenyl benzothiazole derivative. Bioorganic & medicinal chemistry letters. 2018. 28. 4. 707-710
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Lectures and oral presentations (17)：
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高濃度水素含有ゼリーは高脂肪食負荷老化促進マウスの腸管障害を改善する
(第10回日本分子状水素医学生物学会大会 2021)
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高脂肪食およびLPS投与が脳内炎症、神経新生および認知機能の及ぼす影響
(第94回日本薬理学会年会 2021)
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Development of transrepression-selective liver X receptor (LXR) ligands
(2021)
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Transrepression作用選択的LXRリガンドはミクログリアや神経前駆細胞のインフラマソーム活性化を抑制する
(第38回ヒト細胞学会 2020)
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ミクログリアおよび神経前駆細胞のインフラマソーム活性化に対するTransrepression作用選択的LXRリガンドの影響
(第93回日本薬理学会年会 2020)
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Professional career (1)：
- master's degree (The University of Tokyo)
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