2019 - 2021 Development of treatment in pseudomyxoma peritonei: using genome analysis and high-throughput drug screening of patient-derived model
2018 - 2021 Development and application of new biomarkers of malignant bone and soft tissue tumors (sarcomas) using the method of proteogenomics analysis
2017 - 2019 Fundamental research of clinical use for pseudomyxoma peritonei: comprehensive sequencing analysis and generation of transgenic mouse models
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Papers (85)：
Yuki Adachi, Rei Noguchi, Julia Osaki, Takuya Ono, Shuhei Iwata, Taro Akiyama, Ryuto Tsuchiya, Yu Toda, Sekita Tetsuya, Shintaro Iwata, et al. Establishment and characterization of two novel patient-derived cell lines from myxofibrosarcoma: NCC-MFS7-C1 and NCC-MFS8-C1. Human cell. 2024
Kiyoko Takane, Tingwei Cai, Rei Noguchi, Yoshimasa Gohda, Tsuneo Ikenoue, Kiyoshi Yamaguchi, Yasunori Ota, Tomomichi Kiyomatsu, Hideaki Yano, Masaki Fukuyo, et al. Genome-wide analysis of DNA methylation in pseudomyxoma peritonei originated from appendiceal neoplasms. Oncology. 2024
Takuya Ono, Rei Noguchi, Julia Osaki, Taro Akiyama, Yuki Adachi, Naoki Kojima, Yu Toda, Suguru Fukushima, Yuki Yoshimatsu, Akihiko Yoshida, et al. Establishment and characterization of NCC-DFSP5-C1: a novel patient-derived dermatofibrosarcoma protuberans cell line. 2023
Yuki Yoshimatsu, Rei Noguchi, Julia Osaki, Yooksil Sin, Ryuto Tsuchiya, Takuya Ono, Taro Akiyama, Yuki Adachi, Yoshikazu Tanzawa, Akihiko Yoshida, et al. Establishment and characterization of NCC-LMS3-C1: a novel patient-derived cell line of leiomyosarcoma. Human cell. 2023
Rei Noguchi, Yuki Yoshimatsu, Yooksil Sin, Takuya Ono, Ryuto Tsuchiya, Hiroshi Yoshida, Tohru Kiyono, Yutaka Yonemura, Tadashi Kondo. Correction: Noguchi et al. Establishment and Characterization of NCC-PMP1-C1: A Novel Patient-Derived Cell Line of Metastatic Pseudomyxoma Peritonei. J. Pers. Med. 2022, 12, 258. Journal of personalized medicine. 2023. 13. 9
Ryuto Tsuchiya, Yuki Yoshimatsu, Rei Noguchi, Yooksil Sin, Takuya Ono, Akane Sei, Fumitaka Takeshita, Jun Sugaya, Fumihiko Nakatani, Akihiko Yoshida, et al. Establishment and characterization of NCC-ssRMS2-C1: a novel patient-derived cell line of spindle cell/sclerosing rhabdomyosarcoma. Human cell. 2021. 34. 1. 246-253
Tsuchiya Ryuto, Tsuchiya Ryuto, Yoshimatsu Yuki, Noguchi Rei, Sin Yooksil, Ono Takuya, Sei Akane, Takeshita Fumitaka, Sugaya Jun, Nakatani Fumihiko, et al. Establishment and characterization of NCC-ssRMS2-C1: a novel patient-derived cell line of spindle cell/sclerosing rhabdomyosarcoma. Human Cell (Web). 2021. 34. 5
小野拓也, 野口玲, 吉松有紀, Sin Yooksil, 小島伸彦, 近藤格. Development of an in vitro culture system using decellularized tissue gels. 電気泳動(Web). 2021. 65. 2
2023/09 - AOHUPO AOHUPO best posters Drug identification using genomic feature, kinase activity profiles, and drug screening with patient-derived models in giant cell tumor of bone
2023/08 - 日本ヒト細胞学会 Young Investigator Award 優秀賞 患者由来巨細胞腫細胞株を用いた治療法開発:ゲノム情報・キナーゼ活性プロファイル・薬剤感受性試験データを駆使して
2022/11 - HUPO 2022 Travel Award Identification of prognostic candidates using comprehensive kinase activity assay in non-small cell lung cancer biopsy samples
2022/08 - HUPO 2022 Presentation Award Identification of prognostic biomarkers using comprehensive kinase activity assay in non-small cell lung cancer biopsy samples
2022/07 - 日本電気泳動学会 服部賞
2021/08 - HUPO 2021 Presentation Award “OncoProGx”:Innovative proteogenomic software generating sample-specific database for mass spectrometric protein identification
2021/06 - JPros AOHUPO Presentation Award Innovative proteogenomic software “OncoProGx” generating sample-specific database for mass spectrometric protein identification
2019/09 - Human Proteome Organization (HUPO) Human Proteome Project HUPO2019 Clinical Scientist Travel Grants Award Proteogenomic approach focused on osteosarcomas with different original sites: Reported by ICPC JAPAN team
