Rchr
J-GLOBAL ID：202101017045679954   Update date: Jan. 30, 2024

Yamazaki Miwa

ヤマザキ ミワ | Yamazaki Miwa
Affiliation and department：
地方独立行政法人 大阪府立病院機構 大阪母子医療センター 研究所 骨発育疾患研究部門

About 地方独立行政法人 大阪府立病院機構 大阪母子医療センター 研究所 骨発育疾患研究部門


Research theme for competitive and other funds  (2)：
  • 2015 - 2018 Phosphate sensing and expression mechanism of genes responsible for hypophosphatemic rickets in osteocytes: Involvement of Pit1
  • 2012 - 2015 Involvement of the type III sodium phosphate cotransporter Pit-1 in phosphate reabsorption
Papers (26)：
  • Toshimi Michigami, Kanako Tachikawa, Miwa Yamazaki, Tatsuro Nakanishi, Masanobu Kawai, Keiichi Ozono. Growth-related skeletal changes and alterations in phosphate metabolism. Bone. 2022. 161. 116430-116430
  • Miwa Yamazaki, Masanobu Kawai, Saori Kinoshita, Kanako Tachikawa, Tatsuro Nakanishi, Keiichi Ozono, Toshimi Michigami. Clonal osteoblastic cell lines with CRISPR/Cas9-mediated ablation of Pit1 or Pit2 show enhanced mineralization despite reduced osteogenic gene expression. Bone. 2021. 151. 116036-116036
  • Toshimi Michigami, Kanako Tachikawa, Miwa Yamazaki, Masanobu Kawai, Takuo Kubota, Keiichi Ozono. Hypophosphatasia in Japan: ALPL Mutation Analysis in 98 Unrelated Patients. Calcified tissue international. 2020. 106. 3. 221-231
  • Keiko Yamamoto, Masanobu Kawai, Miwa Yamazaki, Kanako Tachikawa, Takuo Kubota, Keiichi Ozono, Toshimi Michigami. CREB activation in hypertrophic chondrocytes is involved in the skeletal overgrowth in epiphyseal chondrodysplasia Miura type caused by activating mutations of natriuretic peptide receptor B. Human molecular genetics. 2019. 28. 7. 1183-1198
  • Masanobu Kawai, Saori Kinoshita, Miwa Yamazaki, Keiko Yamamoto, Clifford J Rosen, Shigeki Shimba, Keiichi Ozono, Toshimi Michigami. Intestinal clock system regulates skeletal homeostasis. JCI insight. 2019. 4. 5
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MISC (14)：
  • Jin Nishino, Kazuaki Miyagawa, Masanobu Kawai, Miwa Yamazaki, Kanako Tachikawa, Yuko Mikuni-Takagaki, Mikihiko Kogo, Keiichi Ozono, Toshimi Michigami. Extracellular Inorganic Phosphate Functions as a Potent Inducer of the Dmp1 Expression and Facilitates the Transition of Osteoblasts to Osteocytes. JOURNAL OF BONE AND MINERAL RESEARCH. 2014. 29. S289-S289
  • Kazuaki Miyagawa, Miwa Yamazaki, Masanobu Kawai, Takao Koshimizu, Jin Nishino, Yasuhisa Ohata, Kanako Tachikawa, Yuko Mikuni-Takagaki, Mikihiko Kogo, Keiichi Ozono, et al. Activation of FGF/FGF Receptor Signaling in the Primary Osteocytes Isolated from Hypophosphatemic Hyp Mice. JOURNAL OF BONE AND MINERAL RESEARCH. 2014. 29. S245-S245
  • Jin Nishino, Kazuaki Miyagawa, Masanobu Kawai, Miwa Yamazaki, Kanako Tachikawa, Yuko Mikuni-Takagaki, Mikihiko Kogo, Keiichi Ozono, Toshimi Michigami. Signaling of Extracellular Inorganic Phosphate Induces the Expression of Dmp1 in Osteoblast/Osteocyte Lineage Cells via Na+/Pi Co-transporter and MEK/ERK Pathway. JOURNAL OF BONE AND MINERAL RESEARCH. 2013. 28
  • Y. Ohata, K. Miyagawa, M. Yamazaki, T. Okada, M. Kawai, K. Ozono, T. Michigami. ANALYSIS OF THE ROLES OF FGF23 IN FETUS - SPECIFIC MINERAL METABOLISM USING HYP MOUSE. OSTEOPOROSIS INTERNATIONAL. 2011. 22. S540-S541
  • Yasuhisa Ohata, Keiichi Ozono, Miwa Yamazaki, Tomoko Okada, Masahiro Nakayama, Haruhiko Hirai, Toshimi Michigami. "PLACENTA EXPRESSES KLOTHO AND FGFR1 IN SYNCYTIOTROPHOBLAST AND CAN RESPOND TO FGF23". PLACENTA. 2010. 31. 9. A153-A153
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