Takai Nobuhiko

Research theme for competitive and other funds (6)：

2021 - 2024 脳腫瘍の集学的治療時に生じる認知機能障害と脳内毛細血管密度の解析
2017 - 2020 The analysis of brain dysfunction due to radiation therapy combined with chemotherapy for brain tumor
2013 - 2016 Research of relative biological effectiveness of the central nervous
2010 - 2012 Early effects on the cognitive function and microvessel density after local brain irradiation with carbon ions
2007 - 2008 Early and late impairments of spatial cognition after local brain irradiation with carbon ions

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Papers (18)：

Nobuhiko Takai, Masatsugu Ohgami, Koichi Ando, Akiko Uzawa, Ryoichi Hirayama, Saori Nakamura, Yoshihito Ohba. THE FOCAL BRAIN PROTON BEAM IRRADIATION INSULT IN RATS - INDUCED MEMORY DISTURBANCE RELATED CHANGE IN ACETYLCHOLINE RECEPTOR BINDING. RAD Conference Proceedings. 2017
Natsuko Kondo, Yoshinori Sakurai, Takushi Takata, Nobuhiko Takai, Yosuke Nakagawa, Hiroki Tanaka, Tsubasa Watanabe, Kyo Kume, Taichiro Toho, Shin-ichi Miyatake, et al. Localized radiation necrosis model in mouse brain using proton ion beams. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 2015. 106. 242-6
Yuka Ishida, Yasushi Ohmachi, Nobuhiko Takai, Takeshi Hiraoka, Toshiaki Ogiu, Tetsu Nishikawa, Yoshikazu Nishimura, Yoshiya Shimada. Neurobehavioral changes in mice exposed to fast neutrons in utero. Journal of radiation research. 2011. 52. 3. 257-63
Ming-Rong Zhang, Katsushi Kumata, Akiko Hatori, Nobuhiko Takai, Jun Toyohara, Tomoteru Yamasaki, Kazuhiko Yanamoto, Joji Yui, Kazunori Kawamura, Sachiko Koike, et al. [11C]Gefitinib ([11c]Iressa): radiosynthesis, in vitro uptake, and in vivo imaging of intact murine fibrosarcoma. Molecular imaging and biology. 2010. 12. 2. 181-91
Tomoya Uehara, Misuzu Nakagawa, Nobuhiko Takai, Sachiko Koike, Yoshiya Furusawa, Kouichi Ando, Keiichi Kawai, Hiromichi Akizawa, Toshiaki Irie, Yasushi Arano. Intracellular reactions affecting 2-amino-4-([(11)C]methylthio)butyric acid ([(11)C]methionine) response to carbon ion radiotherapy in C10 glioma cells. Nuclear medicine and biology. 2009. 36. 8. 985-91

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