Rchr
J-GLOBAL ID:202101019639913704   Update date: Mar. 06, 2024

Shimizu Yu

シミズ ユウ | Shimizu Yu
Affiliation and department:
Job title: Researcher
Research theme for competitive and other funds  (1):
  • 2022 - 2024 構造異常α-defensinの分解阻害機構に着目したクローン病発症機序の解明
Papers (14):
  • Li Gan, Yuga Inamura, Yu Shimizu, Yuki Yokoi, Yuki Ohnishi, Zihao Song, Yasuhiro Kumaki, Takashi Kikukawa, Makoto Demura, Masaaki Ito, et al. A Basic Study of the Effects of Mulberry Leaf Administration to Healthy C57BL/6 Mice on Gut Microbiota and Metabolites. Metabolites. 2023. 13. 9. 1003-1003
  • 清水 由宇, 山村 凌大, 横井 友樹, 綾部 時芳, 鵜川 重和, 中村 幸志, 岡田 恵美子, 今江 章宏, 中川 貴史, 玉腰 暁子, et al. 短眠はPaneth細胞α-defensin分泌量の低値および短鎖脂肪酸の産生量低下を伴う腸内細菌叢組成の撹乱に関係する. 腸内細菌学雑誌. 2023. 37. 2. 112-112
  • Yu Shimizu, Ryodai Yamamura, Yuki Yokoi, Tokiyoshi Ayabe, Shigekazu Ukawa, Koshi Nakamura, Emiko Okada, Akihiro Imae, Takafumi Nakagawa, Akiko Tamakoshi, et al. Shorter sleep time relates to lower human defensin 5 secretion and compositional disturbance of the intestinal microbiota accompanied by decreased short-chain fatty acid production. Gut Microbes. 2023. 15. 1
  • Shunta Nakamura, Kiminori Nakamura, Yuki Yokoi, Yu Shimizu, Shuya Ohira, Mizu Hagiwara, Zihao Song, Li Gan, Tomoyasu Aizawa, Daigo Hashimoto, et al. Decreased Paneth cell α-defensins promote fibrosis in a choline-deficient L-amino acid-defined high-fat diet-induced mouse model of nonalcoholic steatohepatitis via disrupting intestinal microbiota. Scientific Reports. 2023. 13. 1
  • Xuanzhong Chen, Daigo Hashimoto, Ko Ebata, Shuichiro Takahashi, Yu Shimizu, Ryuga Shinozaki, Yuta Hasegawa, Ryo Kikuchi, Hajime Senjo, Kazuki Yoneda, et al. Reactive granulopoiesis depends on T-cell production of IL-17A and neutropenia-associated alteration of gut microbiota. Proceedings of the National Academy of Sciences of the United States of America. 2022. 119. 48. e2211230119
more...
MISC (3):
  • YAMAMURA Ryodai, NAKAMURA Koshi, NAKAMURA Koshi, KITADA Naoya, AIZAWA Tomoyasu, SHIMIZU Yu, NAKAMURA Kiminori, AYABE Tokiyoshi, KIMURA Takashi, TAMAKOSHI Akiko. Associations of gut microbiota, dietary intake, and serum SCFAs with fecal SCFAs. 日本細菌学雑誌(Web). 2020. 75. 1
  • 山村凌大, 鵜川重和, 中村幸志, 木村尚史, 中川貴史, 今江章宏, 國弘忠生, 朴鐘旭, MOHSEN Attayeb, 川島和, et al. Association between archaea and obesity in a general Japanese population: The DOSANCO Health Study. 腸内細菌学雑誌. 2020. 34. 2
  • 木村尚史, 山村凌大, 檜森亮吾, 鵜川重和, 中村幸志, 中川貴史, 今江章宏, 國弘忠生, 朴鐘旭, MOHSEN Attayeb, et al. Association between lean, obesity and gut microbiota in a general Japanese population: The DOSANCO Health Study. 腸内細菌学雑誌. 2020. 34. 2
Lectures and oral presentations  (23):
  • 短眠はPaneth細胞α-defensin分泌量の低値および短鎖脂肪酸の産生量低下を伴う腸内細菌叢組成の撹乱に関係する
    (第27回腸内細菌学会学術集会 2023)
  • Lower secretory level of Paneth cell α-defensin in elderly people is related to aging-associated transition of the intestinal microbiota
    (2022)
  • ER Stress-Associated Misfolding of Paneth cell α-defensin Induces Dysbiosis and Ileitis in a Murine Model of Crohn’s disease
    (World Microbe Forum 2021)
  • α-defensin異常による腸内細菌叢の破綻とIBD
    (第127回日本消化器病学会北海道支部例会 2020)
  • 日本人地域一般住民におけるアーキアと肥満の関連:The DOSANCO Health Study
    (第24回腸内細菌学会学術集会 2020)
more...
Education (4):
  • 2020 - Hokkaido University Graduate School of Life Science
  • 2017 - 2020 Hokkaido University Graduate School of Life Science
  • 2015 - 2017 Hokkaido University Graduate School of Life Science
  • 2011 - 2015 Hokkaido University School of Science Biological Sciences
Work history (6):
  • 2023/04 - 現在 Morinaga Milk Industry Co., Ltd. Health Care and Nutritional Science Institute Researcher
  • 2021/07 - 現在 Hokkaido University Faculty of Advanced Life Science Division of Functional Life Sciences
  • 2020/04 - 2021/06 Hokkaido University Faculty of Advanced Life Science Division of Functional Life Sciences
  • 2017/04 - 2020/03 Hokkaido University Graduate School of Life Science
  • 2015/04 - 2017/03 Hokkaido University Graduate School of Life Science
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Association Membership(s) (3):
腸内細菌学会 ,  日本免疫学会 ,  日本分子生物学会
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