2019 - 2022 Verify if it can be used as a food material to prevent and improve NASH?
2019 - 2020 メタボローム解析技術を応用した食品栄養成分の網羅解析ソフトウェアの開発
2013 - 2016 オートファジー機能調節を介した抗肥満、抗脂肪肝機能性食品の開発
2009 - 2010 天然物由来成分のインフルエンザ予防・治療効果の評価
2006 - 2009 AHCC(担子菌抽出多糖類) 由来の新規感染 症免疫賦活剤の開発
2004 - 2005 関節リウマチ患者用サプリメントに関する研究
2003 - 2004 DEVELOPMENT OF IMMUNE PROMOTIVE MARINE PHOSPHOLIPID BASE LIPOSOMES
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Papers (66):
NATSUKI OTA, SHOYA ENDO, RYOSUKE TATSUNAMI, AOI YAMAGUCHI, KOJI WAKAME, AKIFUMI NAKATA, KEISUKE SATO. Effect of Ganoderma lucidum on Cisplatin-induced Nephrotoxicity and Gastrointestinal Toxicity. ANTICANCER RESEARCH. 2024. 44. 3605-3613
VindyT T, Masataka O, Masashi Y, Tomoko I, Yasuko F, Koji W, Hiroyuki I, Gen-Ichiro S. Baseline data collections of lipopolysaccharide content in 414 herbal extracts and its role in innate immune activation. Scientifc Reports. 2024. 14. 15394
Koji Wakame, Keisuke Sato, Masafumi Kasai, Emi Kikuchi, Kihiro Shimizu, Ako Kudo, Ken-Ichi Komatsu, Akifumi Nakata. Oral Administration of Mulberry (Morus alba L.) Leaf Powder Prevents the Development of Hepatocellular Carcinoma in Stelic Animal Model (STAM) Mice. Anticancer research. 2022. 42. 8. 4055-4062
Seiichi Matsugo, Toshio Sakamoto, Koji Wakame, Yutaka Nakamura, Kenichi Watanabe, Tetsuya Konishi. Mushrooms as a Resource for Mibyou-Care Functional Food; The Role of Basidiomycetes-X (Shirayukidake) and Its Major Components. Nutraceuticals. 2022. 2. 132-149
Takaki Nedachi, Kaoru Haketa, Shinji Harakawa, Naoki Miura, Koji Wakame. Effect of combining sleep-promoting food intake and electric field application on sleep in healthy participants: A pilot study. Functional Foods in Health and Disease. 2021. 11. 12. 659-672
Clinician's Guide to AHCC: Evidence-Based Nutritional Immunotherapy
International Congress on Nutrition and Integrative Medicine (ISBN: 9784990926410) 2016
2006 - The University of Texas, Memorial Hermann Hospital. A nursing program in clinical research: A model of safe and ethical research practice for clinicians (テキサス大学メモリアルハーマン病院 ヒト臨床研究における倫理、安全性に関するプログラム )修了
1998 - 2002 獨協医科大学 医学部 生化学講座 研究生
1991 - 1993 北海道薬科大学大学院 薬学研究科 修士課程
1988 - 1991 北海道薬科大学 薬学部
Professional career (1):
博士(医学) (獨協医科大学)
Work history (12):
2022/04 - 現在 北海道科学大学 薬学部 薬理学分野 教授
2010/04 - 2023/03 National Institutes of Biomedical Innovation, Health and Nutrition