Rchr
J-GLOBAL ID：202101019841944840
Update date: Jan. 09, 2023
Shimada Masako
シマダ マサコ | Shimada Masako
Affiliation and department：
Job title：
Professor
Research field (4)：
Metabolism and endocrinology
, Nutrition and health science
, Cell biology
, Molecular biology
Research keywords (6)：
Osteoblast and Chondrocyte Metabolism
, Obesity
, Dyslipidemia
, Diabetes Mellitus
, Molecular Biology
, Cell Biology
Research theme for competitive and other funds (12)：
- 2017 - 2023 骨密度関連SNPs近隣由来のmiRNAsによる骨代謝制御の検討
- 2018 - 2021 宿主酵素を標的分子とした新規治療薬の開発:高病原性ウイルス感染症の新たな制御法
- 2015 - 2018 The development of the new therapeutic drug which based on the structure of the virus activation enzyme: The new control method of the highly pathogenic infectious diseases.
- 2014 - 2017 Crucial role for Elovl6 during bone development in mice
- 2012 - 2014 Evaluation and exploratory mechanistic analysis; how a novel nano technology increases serum HDL levels by oral administration in mice.
- 2013 - 2014 Development of a new technology for effective bone regeneration using iPS cells
- 2010 - 2012 Dietary calcium-mediated childhood obesity and rapidly increased prevalence of adolescent type 2 diabetes mellitus
- 2011 - 2011 Calpain modulates functions of p27Kip1 in cells of the osteoblast lineage
- 2005 - 2010 Direct Calpain-PTH1R Binding Affects Actions of PTH/PTHrP
- 2003 - 2004 The role of calpain small subunit (Capn4) binding to the parathyroid hormone 1 receptor (PTH1R) on PTH-related peptide (PTHrP)-mediated cell migration and retraction.
- 1993 - 1995 Establishment of animal models for atheroscherosis and gene therapy
- 1992 - 1992 LPLおよびLCAT遺伝子変異に基く高脂血症,低HDL血症の発症メカニズム
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Papers (77)：
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Shihori Watanabe, Shizuko Yamabe, Masako Shimada. Arctium lappa Lam. and Its Related Lignans Improve Hyperglycemia and Dyslipidemia in Diabetic Rodent Models: A Systematic Review and Meta-Analysis. Nutraceuticals. 2022. 2. 4. 335-349
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Shihori Watanabe, Hiyori Okoshi, Shizuko Yamabe, Masako Shimada. Moringa oleifera Lam. in Diabetes Mellitus: A Systematic Review and Meta-Analysis. Molecules. 2021. 26. 12. 3513-3513
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Moe Sasaki, Nami Nishida, Masako Shimada. A Beneficial Role of Rooibos in Diabetes Mellitus: A Systematic Review and Meta-Analysis. Molecules (Basel, Switzerland). 2018. 23. 4
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Nagaoka I, Nishida N, Shimada M. Mechanism underlying Crosstalk between Bone and Adipose tissue. J Metab Clin Nutr. 2016. 19. 4. 397-405
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Manami Kikuchi, Masako Shimada, Takashi Matsuzaka, Kiyoaki Ishii, Yoshimi Nakagawa, Misa Takayanagi, Nobuhiro Yamada, Hitoshi Shimano. Crucial Role of Elovl6 in Chondrocyte Growth and Differentiation during Growth Plate Development in Mice. PloS one. 2016. 11. 7. e0159375
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MISC (4)：
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松坂 賢, 渥美 綾香, 唐 ネ, 煙山 紀子, 久芳 素子, 中川 嘉, 嶋田 昌子, 小林 和人, 矢藤 潔, 高橋 昭光, et al. 非アルコール性脂肪性肝炎における脂肪酸伸長酵素Elovl6の役割. 糖尿病. 2013. 56. Suppl.1. S-128
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H Yagyu, S Ishibashi, C Zhong, J Osuga, M Okazaki, M Shimada, K Ohashi, K Harada, F Shionoiri, N Yahagi, et al. Overexpressed lipoprotein lipase protects against atherosclerosis in apolipoprotein E knockout mice. CIRCULATION. 1998. 98. 17. 2-2
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YAMADA Nobuhiro, SHIMANO Hitoshi, SHIMADA Masako, GOTODA Takanari, ISHIBASHI Shun, YAZAKI Yoshio. Roole of ApoE in the Metabolism of Triglyceride - rich Lipoproteins : Transgenic Mice Overexpressing Apolipoprotein E. Journal of Atherosclerosis and Thrombosis. 1995. 22. 11. 815-818
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山田 信博, 島野 仁, 嶋田 昌子, 後藤田 貴也, 石橋 俊, 矢崎 義雄. トリグリセリド輸送リポ蛋白代謝の解析 : アポEおよびリポ蛋白リパーゼを発現するトランスジェニックマススを中心に. 動脈硬化 = The journal of Japan Atherosclerosis Society. 1994. 22. 1. 70-70
Books (23)：
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Crucial Role of Elovl6 in Chondrocyte Growth and Differentiation during Growth Plate Development in Mice
1st Author The Japanese Society for Bone Mineral Research 2016
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Intellectual Resources of Kanagawa
University Collaboration Journal 2016
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Calpain-mediated Regulation of Bone and Fat Mass and Glucose Homeostasis in Osteoblasts
Nova Science Publishers, Inc. 2013
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MCH knockout mice
The Lipid; Medical View 2006
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Role of melanin concentrating hormone in obesity
The latest medicine 2001
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Education (1)：
- 1982 - 1988 The University of Tokyo Faculty of Medicine School of Medicine
Professional career (1)：
- Ph.D. in Medicine (The University of Tokyo)
Work history (10)：
- 2014/04 - 現在 Sagami Women's University Faculty of Nutritional Science, Department of Nutrition and Health Professor
- 2014/04 - 現在 Sagami Women's University Graduate School of Nutritional Sciences Professot
- 2012/04 - 2014/03 University of Tsukuba Faculty of Medicine Associate Professor
- 2006/04 - 2014/03 Harvard Medical School Assistant Professor of Medicine
- 2002/07 - 2006/03 Harvard Medical School Instructor in Medicine
- 1999/10 - 2002/06 Massachusetts General Hospital, Boston, MA. Endocrine Unit Post-doctoral research fellow
- 1996/09 - 1999/09 Beth Israel Deaconess Medical Center, Boston, MA. Division of Endocrinology Post-doctoral research fellow
- 1995/04 - 1996/06 Toranomon Hospital Division of Metabolism Staff Physician
- 1990/06 - 1995/03 Tokyo University Hopital The third Department of Internal Medicine
- 1988/04 - 1990/03 Toranomon Hospital
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Awards (3)：
- 2011/01 - Harvard University William F. Milton Fund Award
- 2003/07 - American Cancer Society Institutional Research Grant Award for Junior Investigators
- 1996/03 - Banyu Pharmaceutical Co. Ltd., and the Merck Company Foundation Banyu Fellowship Award in Lipid Metabolism & Atherosclerosis The cloning of genes handling hyperlipidemia, obesity and insulin resistance, and therapeutic approach.
Association Membership(s) (5)：
日本病態栄養学会
, 日本臨床栄養学会
, 日本糖尿病学会
, 日本内科学会
, American Society for Bone Mineral Research
