Rchr
J-GLOBAL ID:202101020004016887
Update date: Oct. 07, 2024
Kuroda Shinya
クロダ シンヤ | Kuroda Shinya
Affiliation and department:
Job title:
Professor
Research field (3):
Medical biochemistry
, Systems genomics
, Systems genomics
Research keywords (2):
systems biology
, Trans-omics
Research theme for competitive and other funds (29):
- 2023 - 2028 冬眠生物学2.0 総括班
- 2021 - 2026 時空間トランスオミクスを用いた多細胞・臓器連関代謝制御の解明
- 2021 - 2024 Information coding based in cell-to-cell variability
- 2017 - 2022 Metabolic adaptation of type 2 diabetes
- 2017 - 2022 Trans-omic analysis of metabolic adaptation
- 2017 - 2022 Transomic Analysis of Metabolic Adaptation
- 2019 - 2021 Robust information coding by smallness of neural spines
- 2018 - 2021 Temporal coding of single cell signal transduction
- 2012 - 2017 時間情報コードによる細胞制御システムの解明
- 2012 - 2014 細胞内シグナル伝達機構における時間情報コードのシステム生物学
- 2009 - 2011 高速定量的免疫染色手法と1細胞レベルのシグナル伝達ネットワークの確率的モデル化手法開発
- 2009 - 2011 Systems biology of AKT signaling
- 2006 - 2011 シグナル伝達機構の情報コーディング
- 2005 - 2009 System analysis of stability and plasticity of signal transduction
- 2006 - 2008 Systems biology of ERK signaling networks
- 2003 - 2007 Molecular mechanism underlying cell polarity and cell migration
- 2002 - 2005 シグナル伝達機構のシステム解析
- 2003 - 2004 Systems analysis of molecular networks based on biochemical computational simulations
- 1996 - 1999 細胞接着のダイナミクス
- 1998 - 1998 低分子量G蛋白質とその標的蛋白質による血管構築の分子機構
- 1998 - 1998 低分子量G蛋白質とその標的蛋白質による細胞内情報ネットワークの解析
- 1998 - 1998 低分子量G蛋白質の標的蛋白質とその病態
- 1997 - 1998 Regulation of Cytoskeletons and Cell Adhesions by the Rho Family GTPases.
- 1997 - 1997 低分子量G蛋白質とその標的蛋白質による血管構築の分子機構
- 1997 - 1997 低分子量G蛋白質とその標的蛋白質による細胞内情報ネットワークの解折
- 1997 - 1997 低分子量G蛋白質とその標的蛋白質の相互作用の構造解析
- 1997 - 1997 細胞増殖制御における低分子量G蛋白質の機能と作用機構
- 1996 - 1996 低分子量G蛋白質の標的蛋白質の機能とその病態
- 1996 - 1996 低分子量G蛋白質とその標的蛋白質の相互作用の構造解析
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Papers (121):
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Yifei Pan, Atsushi Hatano, Satoshi Ohno, Keigo Morita, Toshiya Kokaji, Yunfan Bai, Hikaru Sugimoto, Riku Egami, Akira Terakawa, Dongzi Li, et al. Time and dose selective glucose metabolism for glucose homeostasis and energy conversion in the liver. npj Systems Biology and Applications. 2024. 10. 1
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Suguru Fujita, Ken-ichi Hironaka, Yasuaki Karasawa, Shinya Kuroda. Model selection reveals selective regulation of blood amino acid and lipid metabolism by insulin in humans. iScience. 2024. 109833-109833
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Yunfan Bai, Keigo Morita, Toshiya Kokaji, Atsushi Hatano, Satoshi Ohno, Riku Egami, Yifei Pan, Dongzi Li, Katsuyuki Yugi, Saori Uematsu, et al. Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity. iScience. 2024. 27. 3. 109121-109121
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Hideki Maehara, Toshiya Kokaji, Atsushi Hatano, Yutaka Suzuki, Masaki Matsumoto, Keiichi I. Nakayama, Riku Egami, Takaho Tsuchiya, Haruka Ozaki, Keigo Morita, et al. DNA hypomethylation characterizes genes encoding tissue-dominant functional proteins in liver and skeletal muscle. Scientific Reports. 2023. 13. 1
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Yuki Ito, Shinsuke Uda, Toshiya Kokaji, Akiyoshi Hirayama, Tomoyoshi Soga, Yutaka Suzuki, Shinya Kuroda, Hiroyuki Kubota. Comparison of hepatic responses to glucose perturbation between healthy and obese mice based on the edge type of network structures. Scientific reports. 2023. 13. 1. 4758-4758
more...
MISC (22):
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小鍛治 俊也, 幡野 敦, 柚木 克之, 黒田 真也. 【マルチオミクスを使って得られた最新知見 糖尿病・がん・腸内細菌研究における実例と解析法】マウス肝臓における肥満特異的な代謝制御トランスオミクスネットワーク構築. 実験医学. 2020. 38. 8. 1289-1294
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Katsuyuki Yugi, Satoshi Ohno, James R. Krycer, David E. James, Shinya Kuroda. Rate-oriented trans-omics: integration of multiple omic data on the basis of reaction kinetics. Current Opinion in Systems Biology. 2019. 15. 109-120
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Takumi Wada, Mitsutaka Wataya, Masashi Fujii, Ken-ichi Hironaka, Miki Eto, Shinsuke Uda, Daisuke Hoshino, Katsuyuki Kunida, Haruki Inoue, Hiroyuki Kubota, et al. Single-cell information analysis reveals small intra- and large intercellular variations increase cellular information capacity. bioRxiv. 2019
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Katsuyuki Yugi, Shinya Kuroda. Metabolism as a signal generator across trans-omic networks at distinct time scales. Current Opinion in Systems Biology. 2018. 8. 59-66
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Katsumi Konishi, Masashi Fujii, Katsuyuki Kunida, Shinsuke Uda, Shinya Kuroda. Matrix rank minimization approach to signal recovery and nonlinear function estimation for nonlinear ARX model with input nonlinearity. 2017 Asian Control Conference, ASCC 2017. 2018. 2018-. 1428-1431
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Lectures and oral presentations (2):
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Transomic network analysis of glucose metabolism and its dysfunction associated with obesity
(2023 5th MHRC Symposium at SIMS 2023)
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トランスオミクスによる肝臓での糖応答システムの解析
(東海糖尿病代謝連携懇話会学術講演会 2023)
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