MITA Marie

ミタマリエ | MITA Marie

Affiliation and department：

Research field (2)： Physiology , Molecular biology

Research keywords (9)： fluorescent protein , single FP-based indicators , live-cell imaging , cell signaling , glucose metabolism , glucose , peptide hormone , insulin , incretin

Research theme for competitive and other funds (4)：

2023 - 2026 メダカin vivoイメージングによる低酸素下での仮死化機構の解析
2022 - 2024 細胞間隙の分子動態可視化による神経活動抑制の脳内伝播メカニズム解明
2020 - 2022 生細胞イメージングによる脳神経系の代謝制御機構の解明
2018 - 2019 グルコース代謝を可視化する新規蛍光型分子センサーの開発

Papers (9)：

Marie Mita, Tetsuya Kitaguchi. 生体分子を「みえる化」する技術-単色蛍光タンパク質センサーの革新-. Folia Pharmacologica Japonica. 2024. 159. 1. 13-17
Saki Tsuno, Kazuki Harada, Mina Horikoshi, Marie Mita, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi. Mitochondrial ATP concentration decreases immediately after glucose administration to glucose-deprived hepatocytes. FEBS open bio. 2024. 14. 1. 79-95
Mai Takizawa, Yuri Osuga, Rika Ishida, Marie Mita, Kazuki Harada, Hiroshi Ueda, Tetsuya Kitaguchi, Takashi Tsuboi. Development of a red fluorescent protein-based cGMP indicator applicable for live-cell imaging. Communications Biology. 2022. 5. 1
Marie Mita, Izumi Sugawara, Kazuki Harada, Motoki Ito, Mai Takizawa, Kentaro Ishida, Hiroshi Ueda, Tetsuya Kitaguchi, Takashi Tsuboi. Development of red genetically encoded biosensor for visualization of intracellular glucose dynamics. Cell Chemical Biology. 2021. 29. 1. 98-108
Marie Mita, Devina Wongso, Hiroshi Ueda, Takashi Tsuboi, Tetsuya Kitaguchi. Development of a Single Fluorescent Protein-Based Green Glucose Indicator by Semirational Molecular Design and Molecular Evolution. Methods in Molecular Biology. 2021. 2274. 89-100

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MISC (4)：

Tsuno saki, harada kazuki, horikoshi mina, Mita Marie, Kitaguchi tetsuya, Hirai yumi, Matsumoto mitsuharu, Tsuboi takashi. Imaging analysis of metabolic kinetics in hepatocytes during glucose depletion and reperfusion. 2024
Osuga Yuri, Takizawa Mai, Ishida Rica, Mita Marie, Harada Kazuki, Kitaguchi Tetsuya, Tsuboi Takashi. Intracelular cGMP dynamics during incretin secretion revealed by red fluorescent protein-based cGMP sensor. 2023
Tsuno Saki, Harada Kazuki, Horikoshi Mina, Mita Marie, Kitaguchi Tetsuya, Hirai yumi, Matsumoto mitsuharu, Tsuboi Takashi. Visualization analysis of intracellular metabolites during metabolic switching in hepatocytes. 2023
Mita marie, Tsuboi takashi. 小腸内分泌L細胞に対する人工甘味料スクラロースの作用. 2021. 83. 1. 14-14

Books (2)：

Make the invisible visible - Innovation in the single fluorescent protein-based indicators -
The Japanese Pharmacological Society 2024
Progress and prospects of technology in glucose detection in vitro and in vivo
The New Science Co., Ltd. 2023

Lectures and oral presentations (6)：

遺伝子コード型蛍光センサーの開発とオキシトシン分泌イメージングの展望
(第49回日本神経内分泌学会学術集会 2023)
生体内のエネルギーを可視化する技術
(若手・超若手の交流会 ~研究者ってどんな職業?~ 2021)
なぜ科学が楽しいのか!?~東大生に聞く私は中高生の時こうだった~
(市民大学認定講座男女共同参画フォーラム 2021)
小腸内分泌L細胞に対する人工甘味料スクラロースの作用
(第250回生理学東京談話会 2020)
生細胞内のグルコース動態を検出する遺伝子コード型緑色蛍光センサーの創出
(2019年度日本生化学会関東支部例会 2019)

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Education (3)：

2018 - 2021 The University of Tokyo Graduate School of Arts and Sciences Multi-Disciplinary Sciences Life Sciences
2016 - 2018 The University of Tokyo Graduate School of Arts and Sciences Multi-Disciplinary Sciences Life Sciences
2012 - 2016 Gakushuin University Faculty of Science Department of Life Science

Professional career (2)：

修士(学術) (東京大学)
博士(学術) (東京大学)

Work history (2)：

2022/04 - 現在 National Institute of Advanced Industrial Science and Technology Biomedical Research Institute
2021/04 - 2022/03 The University of Tokyo Graduate School of Arts and Sciences Japan Society for the Promotion of Science (JSPS PD)

Committee career (1)：

IUPAB2024 https://www.c-linkage.co.jp/iupab2024-bsj-kyoto/

Awards (4)：

2019/06 - The Japanese biochemical society Presentation award
2019/04 - The University of Tokyo BIO UT 2020 poster award
2019/03 - The japan science society Sasakawa Scientific Research Award
2018/03 - Graduate School of Arts and Sciences, The University of Tokyo Outstanding Graduate Student Award

Association Membership(s) (3)：

The Zoological Society of Japan , The Physiological Society of Japan , The Molecular Biology Society of Japan

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