Hisa Hiroaki

ヒサヒロアキ | Hisa Hiroaki

Affiliation and department：

Research field (1)： Pharmacology

Research keywords (1)： renal sympathetic nervous system and renal injury

Research theme for competitive and other funds (16)：

2002 - 2004 Drug development by signal transduction therapy in the ischemic brain injury.
1999 - 2000 副腎におけるコリン作動性神経伝達の解析系の確立
1998 - 1999 L並びにN型カルシウムチャネル拮抗作用を併有する降圧薬の開発に関する薬理学的研究
1998 - 1999 Development of the dual inhibitor of angiotensin-converting enzyme and neutral endopeptidase as the drugs of chronic heart failure
1998 - 1998 内因性アセチルコリンに誘起される副腎カテコールアミン分泌の解析システムの構築

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Papers (92)：

Shiba Tatsuo, Totoribe Naoko, Gamoh Shuji, Yokota Atsuko, Nakamura Eisaku, Kuwabara Masachika, Hisa Hiroaki, Yamamoto Ryuichi. The effect of M-1, a major metabolite of sarpogrelate, on 5-hydroxytryptamine-mediated vasoconstriction in isolated human internal thoracic artery. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2019. 92. 1-P-067
Masahiro Ohsawa, Kei-Ichiro Ishikura, Junpei Mutoh, Hiroaki Hisa. Involvement of inhibition of RhoA/Rho kinase signaling in simvastatin-induced amelioration of neuropathic pain. Neuroscience. 2016. 333. 204-13
Masahiro Ohsawa, Junpei Mutoh, Shohei Yamamoto, Hiroaki Hisa. Involvement of protein isoprenylation in neuropathic pain induced by sciatic nerve injury in mice. NEUROSCIENCE LETTERS. 2014. 564. 27-31
Junpei Mutoh, Masahiro Ohsawa, Hiroaki Hisa. Involvement of renal sympathetic nerve activation on the progression of ischemic acute kidney injury in the mouse. Journal of pharmacological sciences. 2014. 125. 4. 415-21
Shuji Gamoh, Hiroaki Hisa, Ryuichi Yamamoto. 5-hydroxytryptamine receptors as targets for drug therapies of vascular-related diseases. Biological and Pharmaceutical Bulletin. 2013. 36. 9. 1410-1415

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MISC (9)：

Tasuku Kanai, Shuji Gamoh, Naoko Totoribe, Masachika Kuwabara, Eisaku Nakamura, Hiroaki Hisa, Ryuichi Yamamoto. Exendin-4, a glucagon-like peptide-1 analogue, inhibits 5-hydroxytryptamine-induced vasocontraction in the isolated human endothelium-denuded saphenous vein. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2013. 121. 204P-204P
Tasuku Kanai, Masachika Kuwabara, Naoko Totoribe, Yasuko Matsuo, Eisaku Nakamura, Shuji Gamoh, Akito Suzuki, Yujiro Asada, Hiroaki Hisa, Ryuichi Yamamoto. Internalization of the plasma membrane 5-hydroxytryptamine2A (5-HT2A) receptor Induced by insulin in the isolated human endothelium-denuded saphenous vein. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2012. 118. 83P-83P
Tasuku Kanai, Yasuko Matuo, Naoko Tanaka, Masachika Kuwabara, Eisaku Nakamura, Hiroaki Hisa, Ryuichi Yamamoto. Insulin-induced NO-independent vasodilation in the human endothelium-denuded saphenous vein. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2011. 115. 107P-107P
Naoko Tanaka, Tasuku Kanai, Yasuko Matsuo, Masachika Kuwabara, Eisaku Nakamura, Kunihide Nakamura, Yujiro Asada, Hiroaki Hisa, Ryuichi Yamamoto. Relative contributions of Rho-kinase to the constrictions of human isolated internal thoracic artery and saphenous vein. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2010. 112. 85P-85P
Junpei Mutoh, Masahiro Ohsawa, Hiroaki Hisa. An opioid kappa receptor antagonist nor-binaltorphimine improves ischemia/reperfusion-induced renal dysfunction in mice. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2009. 109. 197P-197P

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Books (7)：

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Education (1)：

Professional career (1)：

Awards (3)：

Association Membership(s) (3)：

日本薬学会会員 , 日本薬理学会学術評議員 , 日本薬理学会会員

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