Rchr
J-GLOBAL ID：202201000193284451
Update date: Nov. 11, 2024
Tsuchitani Toshiaki
ツチタニ トシアキ | Tsuchitani Toshiaki
Affiliation and department：
Job title：
Assistant Professor
Other affiliations (1)：
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Josai International University
Research field (1)：
Clinical pharmacy
Research keywords (5)：
PBPKモデル
, modeling&simulation
, in vitro-to-in vivo extrapolation
, Transporter
, Pharmacokinetics
Research theme for competitive and other funds (2)：
- 2022 - 2024 Establishment of a novel methodology for estimating pharmacological target occupancy and therapeutic dosage in Phase I clinical trials for drug development.
- 2015 - 2018 The effect of gastrointestinal damage on drug absorption
Papers (7)：
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Toshiaki Tsuchitani, Atsuko Tomaru, Yasunori Aoki, Naoki Ishiguro, Yasuhiro Tsuda, Yuichi Sugiyama. Elucidating nonlinear pharmacokinetics of telmisartan: Integration of target-mediated drug disposition and OATP1B3-mediated hepatic uptake in a physiologically based model. CPT: Pharmacometrics & Systems Pharmacology. 2024
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Hongye Han, Takeshi Akiyoshi, Tokio Morita, Toshiaki Tsuchitani, Momoko Nabeta, Kodai Yajima, Ayuko Imaoka, Hisakazu Ohtani. The Effects of Jabara Juice on the Intestinal Permeation of Fexofenadine. Biological & pharmaceutical bulletin. 2023. 46. 12. 1745-1752
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Masami Tsuchiya, Manit Saeteaw, Suphat Subongkot, Trai Tharnpanich, Jitprapa Konmun, Izumi Nasu, Yumiko Shimanuki, Toshiaki Tsuchitani, Mio Ezura, Koji Hashiguchi, et al. Using an online journal club to improve Asian speakers' comfort in using English to discuss and understand research papers written in English. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners. 2022. 10781552221107548-10781552221107548
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Toshiaki Tsuchitani, Takeshi Akiyoshi, Ayuko Imaoka, Hisakazu Ohtani. Mechanistic bottom-up estimation of passive drug absorption from the gastrointestinal tract: Comparison among primary cultured human intestinal cells, Caco-2 cells, artificial membrane, and animal scale-up. International journal of clinical pharmacology and therapeutics. 2022. 60. 5. 217-224
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Tokio Morita, Takeshi Akiyoshi, Toshiaki Tsuchitani, Hiroki Kataoka, Naoya Araki, Kodai Yajima, Kazuhiro Katayama, Ayuko Imaoka, Hisakazu Ohtani. Inhibitory Effects of Cranberry Juice and Its Components on Intestinal OATP1A2 and OATP2B1: Identification of Avicularin as a Novel Inhibitor. Journal of agricultural and food chemistry. 2022. 70. 10. 3310-3320
ｍore...
MISC (1)：
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土谷 聡耀. 第16回 留学とは「自分」を知ること:自らの文化と特性を理解し薬学の未来に生かす. ファルマシア. 2019. 55. 12. 1160-1161
Education (2)：
- 2018 - 2022 Keio University Graduate School of Pharmaceutical Sciences (Doctoral)
- 2012 - 2018 Keio University Faculty of Pharmacy Department of Pharmacy
Professional career (2)：
- Ph.D. (Keio University)
- B.S. (Keio University)
Work history (3)：
- 2024/08 - 現在 Keio University Faculty of Pharmacy, Division of Pharmaceutics Assistant Professor
- 2022/10 - 現在 Josai International University
- 2022/07 - 2024/08 ShanghaiTech University iHuman Institute Postdoctoral researcher
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