Mizuno Tadahaya

Mizuno Tadahaya | Mizuno Tadahaya

Affiliation and department：
Job title： assistant professor

Research field (4)： Biological, health, and medical informatics , Clinical pharmacy , Clinical pharmacy , Clinical pharmacy

Research keywords (6)： toxicology , representation learning , latent variable model , Pharmacoinformatics , Chemoinformatics , Bioinformatics

Research theme for competitive and other funds (16)：

2022 - 2025 In situ多層オミクスとリアルワールドデータ活用による口腔がん分子標的探索
2022 - 2025 Development of enzymomics platform for characterization of disease-related alterations of enzymatic activities
2022 - 2024 ニューロンの多階層エピジェネティクス情報の潜在変数モデルによる記憶の解明
2022 - 2024 Mechanism of constituting a cancer cell population resistant to molecular-targeted drugs
2021 - 2024 健康長寿社会の実現に資する革新的低コスト医療創製基盤の構築

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Papers (24)：

Hiroki Kondou, Satoshi Nakano, Tadahaya Mizuno, Kazuhiko Bessho, Yasuhiro Hasegawa, Atsuko Nakazawa, Ken Tanikawa, Yoshihiro Azuma, Tatsuya Okamoto, Ayano Inui, et al. Clinical symptoms, biochemistry, and liver histology during the native liver period of progressive familial intrahepatic cholestasis type 2. Orphanet journal of rare diseases. 2024. 19. 1. 57-57
Ryutaro Tamura, Yusuke Sabu, Tadahaya Mizuno, Seiya Mizuno, Satoshi Nakano, Mitsuyoshi Suzuki, Daiki Abukawa, Shunsaku Kaji, Yoshihiro Azuma, Ayano Inui, et al. Intestinal Atp8b1 dysfunction causes hepatic choline deficiency and steatohepatitis. Nature communications. 2023. 14. 1. 6763-6763
Hiromu Ishiguro, Tadahaya Mizuno, Yasuo Uchida, Risa Sato, Hayate Sasaki, Shumpei Nemoto, Tetsuya Terasaki, Hiroyuki Kusuhara. Characterization of proteome profile data of chemicals based on data-independent acquisition MS with SWATH method. NAR Genomics and Bioinformatics. 2023. 5. 1
Tatsuki Mochizuki, Maciej J Zamek-Gliszczynski, Kenta Yoshida, Jialin Mao, Kunal Taskar, Hideki Hirabayashi, Xiaoyan Chu, Yurong Lai, Tadayuki Takashima, Kevin Rockich, et al. Effect of Cyclosporin A and Impact of Dose Staggering on OATP1B1/1B3 Endogenous Substrates and Drug Probes for Assessing Clinical Drug Interactions. Clinical pharmacology and therapeutics. 2022. 111. 6. 1315-1323
Yoko Nakajima, Shuhei Osaka, Tadahaya Mizuno, Katsuyuki Yokoi, Satoshi Nakano, Saeko Hirai, Yuka Hiraoka, Yoshiki Miura, Mitsuyoshi Suzuki, Hiroyuki Kusuhara, et al. Influence of food on pharmacokinetics and pharmacodynamics of 4-phenylbutyrate in patients with urea cycle disorders. Molecular genetics and metabolism reports. 2021. 29. 100799-100799

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MISC (3)：

Nakajima Yoko, Osaka Shuhei, Mizuno Tadahaya, Yokoi Katsuyuki, Nakano Satoshi, Hirai Saeko, Suzuki Mitsuyoshi, Kusuhara Hiroyuki, Hayashi Hisamiysu. Influence of food on pharmacokinetics of 4-phenylbutyrate in patients with urea cycle disorders(和訳中). 日本先天代謝異常学会雑誌. 2021. 37. 160-160
Kensuke Aida, Hisamitsu Hayashi, Kaori Inamura, Tadahaya Mizuno, Yuichi Sugiyama. UBIQUITINATION IS ASSOCIATED WITH THE INTERNALIZATION OF BILE SALT EXPORT PUMP (BSEP/ABCB11) FROM THE PLASMA MEMBRANE. HEPATOLOGY. 2011. 54. 725A-726A
Tadahaya Mizuno, Hisamitsu Hayashi, Yuichi Sugiyama. Ubiquitination Is Associated With Degradation of ATP-binding Cassette Transporter A1 (ABCA1) On Cell Surface. DRUG METABOLISM REVIEWS. 2010. 42. 308-309

Education (3)：

2009 - 2014 The University of Tokyo Laboratory of Molecular Pharmacokinetics Graduate School of Pharmaceutical Sciences
2005 - 2009 The University of Tokyo Faculty of Pharmaceutical Sciences
2002 - 2005 神奈川県立柏陽高校

Work history (1)：

2014/04 - 現在 The University of Tokyo Laboratory of Molecular Pharmacokinetics Graduate School of Pharmaceutical Sciences

Awards (1)：

2021/09 - 日本薬学会関東支部日本薬学会関東支部奨励賞薬物の包括的な作用理解を実現する作用分離解析の開発

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