Rchr
J-GLOBAL ID:202201004180314942
Update date: Oct. 21, 2024
Kiyotani Kazuma
キヨタニ カズマ | Kiyotani Kazuma
Affiliation and department:
Research field (2):
Tumor diagnostics and therapeutics
, Tumor biology
Research theme for competitive and other funds (14):
- 2024 - 2027 空間的トランスクリプトームとマルチオミクスによる食道癌の新規免疫治療分子の同定
- 2021 - 2024 遺伝子改変ネオアンチゲン特異的T細胞による泌尿器癌個別化免疫療法の開発
- 2021 - 2024 CDK4/6阻害剤による抗腫瘍免疫応答活性化の解析と新規多剤併用免疫療法への応用
- 2020 - 2023 子宮頸癌におけるWEE1阻害薬の検討およびその免疫環境の評価
- 2020 - 2023 新規免疫治療創出を目指したMSI-low上部消化管腺癌の網羅的免疫・ゲノム解析
- 2019 - 2022 Exploration of novel therapeutic targets for renal cancer by multi-omics analysis and development of treatment algorithm
- 2019 - 2022 間質応答を利用したホルモン受容体陽性乳がんの治療戦略の構築
- 2019 - 2022 Comprehensive analysis of cancer-specific antigens recognized by tumor-infiltrating T cells
- 2018 - 2021 Identification of predictive biomarkers for immune checkpoint inhibitors using T cell receptor repertoire analysis
- 2018 - 2021 Immunogenomic landscape of gynecologic carcinosarcoma
- 2018 - 2020 Investigation of neo-self antigens derived from proteins with post-translational modification
- 2012 - 2012 次世代シークエンサーによる新規乳がん関連遺伝子の探索
- 2010 - 2011 Identification of polymorphisms in drug-transporter genes associated with clinical outcome of adjuvant tamoxifen therapy for breast cancer patients
- 2007 - 2009 Effects of protein/protein interaction on activity of drug metabolizing enzymes
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Papers (103):
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Hiroaki Hiramatsu, Rui Yokomori, Liu Shengyi, Norio Tanaka, Seiichi Mori, Kazuma Kiyotani, Osamu Gotoh, Shigeru Kusumoto, Nobuaki Nakano, Youko Suehiro, et al. Clinical landscape of TP73 structural variants in ATL patients. Leukemia. 2023
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Mizuki Haraguchi, Kazuma Kiyotani, Tomohiro Tate, Seiji Sakata, Ray Sagawa, Satoshi Takagi, Satoshi Nagayama, Kengo Takeuchi, Kazuhisa Takahashi, Ryohei Katayama. Spatiotemporal commonality of the TCR repertoire in a T-cell memory murine model and in metastatic human colorectal cancer. Cancer immunology, immunotherapy : CII. 2023. 72. 9. 2971-2989
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Yuriko Minegishi, Kazuma Kiyotani, Kensaku Nemoto, Yoshikage Inoue, Yoshimi Haga, Risa Fujii, Naomi Saichi, Satoshi Nagayama, Koji Ueda. Differential ion mobility mass spectrometry in immunopeptidomics identifies neoantigens carrying colorectal cancer driver mutations. Communications biology. 2022. 5. 1. 831-831
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Kazumi Okamura, Satoshi Nagayama, Tomohiro Tate, Hiu Ting Chan, Kazuma Kiyotani, Yusuke Nakamura. Lymphocytes in tumor-draining lymph nodes co-cultured with autologous tumor cells for adoptive cell therapy. Journal of Translational Medicine. 2022. 20. 1. 241-241
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Kosuke Nakano, Yoko Koh, Gaku Yamamichi, Satoru Yumiba, Eisuke Tomiyama, Makoto Matsushita, Yujiro Hayashi, Cong Wang, Yu Ishizuya, Yoshiyuki Yamamoto, et al. Perioperative circulating tumor DNA enables the identification of patients with poor prognosis in upper tract urothelial carcinoma. Cancer science. 2022. 113. 5. 1830-1842
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MISC (22):
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清谷一馬. Development of neoantigen-targeted T cell therapy. 月刊腫瘍内科. 2021. 27. 5. 563-569
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清谷 一馬, 豊島 雄二郎. 【がん治療における個別化医療の潮流】ネオ抗原を標的とした新規T細胞療法の開発. Precision Medicine. 2020. 3. 14. 1299-1302
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宮内 栄作, 松田 達雄, Hsu Yu-Wen, 突田 容子, 一ノ瀬 正和, 桜田 晃, 岡田 克典, 齊藤 涼子, 清谷 一馬, 中村 祐輔. EGFR遺伝子変異陽性肺腺癌におけるT細胞受容体レパトア解析(T cell receptor repertoire analysis of lung adenocarcinoma harboring EGFR mutations). 日本癌学会総会記事. 2018. 77回. 2036-2036
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清谷一馬, 中村祐輔. Pharmacogenomicsに基づく乳がんホルモン療法の個別化. がん分子標的治療. 2018. 16. 2. 178-184
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宮川 義仁, 小松 正人, 清谷 一馬, 吉丸 哲郎, 本田 純子, 笹 三徳, 三好 康雄, 片桐 豊雅. トリプルネガティブ乳癌における癌抑制遺伝子BCLR1の発現低下について. 日本癌学会総会記事. 2015. 74回. J-1227
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Lectures and oral presentations (73):
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腫瘍組織解析とctDNAを併用した肺癌術後のモニタリング法はMinimal residual disease検出率を向上させる
(日本呼吸器外科学会総会(Web) 2022)
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SALL3のエピゲノム異常はトリプルネガティブ乳癌の薬剤抵抗性の一因となる
(日本癌学会学術総会抄録集(Web) 2021)
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共通ネオアンチゲンのスクリーニング
(日本癌学会学術総会抄録集(Web) 2021)
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末梢血T細胞受容体レパトア解析を用いた免疫チェックポイント阻害剤早期奏効予測バイオマーカーの開発
(日本癌学会学術総会抄録集(Web) 2021)
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日本人家族性乳癌家系の新規感受性遺伝子の解析
(日本人類遺伝学会大会プログラム・抄録集 2021)
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Work history (7):
- 2023/04 - 現在 National Institutes of Biomedical Innovation, Health and Nutrition Center for Intractable Diseases and ImmunoGenomics Project Leader
- 2017/01 - 現在 Japanese Foundation for Cancer Research Project for Immunogenomics, Cancer Precision Medicine Center Group Leeder
- 2013/04 - 2016/12 The University of Chicago, Chicago Department of Medicine Research Professional
- 2011/05 - 2013/03 The University of Tokushima Division of Genome Medicine, Institute for Genome Research Assistant Professor
- 2008/04 - 2011/04 RIKEN Laboratory for Pharmacogenetics, Center for Genomic Medicine Research Scientist
- 2007/04 - 2008/03 RIEKN Laboratory for Pharmacogenetics, SNP Research Center Research Scientist
- 2006/04 - 2007/03 Takasaki University of Health and Welfare Faculty of Pharmacy Assistant Professor
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Committee career (2):
- - 現在 日本バイオセラピィ学会 評議員
- - 現在 日本癌学会 評議員
Awards (1):
- 2018 - Japanese Cancer Association Young Investigator Awards
Association Membership(s) (3):
米国癌学会
, 日本バイオセラピィ学会
, Japanese Cancer Association
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