SANO SOICHI

サノソウイチ | SANO SOICHI

Affiliation and department：
Job title： Laboratory of Cardiovascular Mosaicism

Research field (2)： Cardiology , Genomics

Research keywords (7)： Somatic mosaicism , Somatic mutations , Somatic loss of sex chromosome , Clonal hematopoiesis , Cardiovascular disease , 炎症 , ゲノム編集

Research theme for competitive and other funds (12)：

2020 - 2025 Role of therapy-related clonal hematopoiesis in anthracycline-induced cardiotoxicity
2022 - 2025 Hematopoietic Y chromosome genes and its association to heart failure progression
2023 - 2025 心房細動とその合併症の早期発見・予防に向けたY染色体欠失血液についての研究
2023 - 2024 X染色体ミステリー:女性の血液の後天的 X 染色体喪失についての研究
2022 - 2024 心不全の予後を左右するY染色体遺伝子の決定

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Papers (50)：

Junichi Tsuchiya, Yoshinori Maki, Madoka Ayano, Taiki Kikuchi, Yosuke Watanabe, Kiyoshi Ohtake, Rumi Fujita, Masaru Hayashi, Junji Yamamoto, Ying Wang, et al. A Novel Method for Acquired Sex Chromosome Mosaicism. Advanced Biology. 2024
Keita Horitani, Nicholas W. Chavkin, Yohei Arai, Ying Wang, Hayato Ogawa, Yoshimitsu Yura, Megan A. Evans, Jesse D. Cocharan, Mark C. Thel, Ariel H. Polizio, Miho Sano, Emiri Miura-Yura, Yuka Arai, et al. Disruption of the Uty epigenetic regultor locus in hematopoietic cells phenoicopies the profibrotic attributes of Y chromiosome loss in heart failure. Nature Cardiovascular Research. 2024. 3. 343-355
Soichi Sano, Kenneth Walsh. Mosaic loss of chromosome Y and cardiovascular disease. Nature Reviews Cardiology. 2023. 2023. 6
Soichi Sano, Kenneth Walsh. Development of a Mouse Model of Hematopoietic Loss of Y Chromosome. BIO-PROTOCOL. 2023. 13. 15. e4729
Soichi Sano, Mark C Thel, Kenneth Walsh. Mosaic Loss of Y Chromosome in White Blood Cells: Its Impact on Men's Health. Physiology (Bethesda, Md.). 2023. 38. 4

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Books (10)：

加齢とともに増加する性染色体欠失細胞
検査と技術・医学書院 2024 ISBN:9784260053853
腫瘍循環器学
日本臨牀・日本臨牀社 2024
クローン性造血と心血管疾患
Medical Practice・文光堂 2024
老化とCHIP
日本臨牀・日本臨牀社 2024
Inflammatory hypothesis
2023 ISBN:9784758125741

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Lectures and oral presentations (27)：

Somatic loss of sex chromosome
(Rocca Life Science Meeting 2024)
ぼくらはモザイクにんげん
(第28回令和私塾共創の場 2024)
会長特別企画循環器内科臨床医として知らないわけにはいかないクローン性造血 Clonal Hematopoiesis and Cardiovascular Disease - Knowns and Unknowns
(第88回日本循環器学会学術集会 2024)
血液の性染色体喪失
(心血管代謝週間CVMW2023 2023)
Y染色体喪失と個体老化
(第46回日本分子生物学会年会 2023)

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Education (1)：

2014 - 2018 Osaka City University Graduate School of Medcine Department of Cardiology

Professional career (2)：

Ph.D. (Osaka City University, Graduate School of Medicine)
M.D. (Osaka City University, Medical School)

Work history (5)：

2023/04 - 現在 National Cerebral and Cardiovascular Center, Research Institute Laboratory of Cardiovascular Mosaicism Independent Derector
2022/04 - 2023/03 大阪公立大学大学院医学研究科循環器内科学特任講師
2019/06 - 2021/03 University of Virginia Department of Cardiovascular Medicine Assistant professor
2018/04 - 2019/05 University of Virginia Cardiovascular Research Center (CVRC) Research associate
2014/09 - 2018/03 Boston University Whitaker Cardiovascular Institute Postdoctoral associate

Committee career (2)：

2024 - 現在国立循環器病研究センター研究所の将来を考える会
2019 - National Health Institute (NIH) Study section

Awards (2)：

2023/03 - 大阪市医学会第1回鈴木衣子賞
2018/03 - 大阪市立大学大学院医学研究科博士課程医学部総代

Association Membership(s) (3)：

心臓病学会 , American Heart Association(AHA) , 日本循環器学会

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