Rchr
J-GLOBAL ID：202201004856726971
Update date: Mar. 04, 2024
Saito Saki
Saito Saki
Affiliation and department：
Research field (1)：
Molecular biology
Research keywords (4)：
エンハンサー
, プロモーター
, 遺伝子発現制御
, 核内受容体
Research theme for competitive and other funds (4)：
- 2023 - 2025 網羅的 eRNA 発現解析による薬剤応答性エンハンサーの同定と機能解析
- 2020 - 2023 翻訳開始因子 Int6/eIF3e のリン酸化修飾を介した癌悪性化機構の解明
- 2018 - 2021 翻訳開始因子 Int6/eIF3e の翻訳後修飾を介した癌悪性化機構の解明
- 2016 - 2020 Investigation of the role of PXR-SGK2 signaling in drug-induced diabetes
Papers (18)：
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Saki Gotoh-Saito, Daichi Sadato, Futoshi Shibasaki. INT6/eIF3e represses E-cadherin expression through HIF2α in lung carcinoma A549 cells. Genes to cells : devoted to molecular & cellular mechanisms. 2022
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Tomomi Morikawa, Tatsuki Fukami, Saki Gotoh-Saito, Masataka Nakano, Miki Nakajima. PPARα regulates the expression of human arylacetamide deacetylase involved in drug hydrolysis and lipid metabolism. Biochemical pharmacology. 2022. 199. 115010-115010
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Sawako Shindo, Shih-Heng Chen, Saki Gotoh, Kosuke Yokobori, Hao Hu, Manas Ray, Rick Moore, Kiyoshi Nagata, Jennifer Martinez, Jau-Shyong Hong, et al. Estrogen receptor α phosphorylated at Ser216 confers inflammatory function to mouse microglia. Cell communication and signaling : CCS. 2020. 18. 1. 117-117
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Saki Gotoh-Saito, Takayuki Abe, Yoichi Furukawa, Shingo Oda, Tsuyoshi Yokoi, Moshe Finel, Masahiko Hatakeyama, Tatsuki Fukami, Miki Nakajima. Characterization of human UGT2A3 expression using a prepared specific antibody against UGT2A3. Drug metabolism and pharmacokinetics. 2019. 34. 4. 280-286
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Takaya Kutsukake, Yoichi Furukawa, Kyoko Ondo, Saki Gotoh, Tatsuki Fukami, Miki Nakajima. Quantitative Analysis of UDP-Glucuronosyltransferase Ugt1a and Ugt2b mRNA Expression in the Rat Liver and Small Intestine: Sex and Strain Differences. Drug metabolism and disposition: the biological fate of chemicals. 2019. 47. 1. 38-44
ｍore...
MISC (1)：
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Saki Gotoh, Masahiko Negishi, Susumu Kodama. LIGANDED PXR FACILITATES BINDING OF SERUM/GLUCOCORTICOID REGULATED KINASE 2 ISOFORM ALPHA TO THE G6PASE PROMOTER TO ACTIVATE IT. DRUG METABOLISM REVIEWS. 2012. 44. 33-33
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