Rchr
J-GLOBAL ID:202201005248398640   Update date: Oct. 09, 2024

Fujii Takuto

フジイ タクト | Fujii Takuto
Affiliation and department:
Job title: Assistant Professor
Research field  (6): Physiology ,  Pharmacology ,  Biophysics ,  Cell biology ,  Molecular biology ,  Tumor biology
Research keywords  (10): 分子生理学 ,  膜輸送 ,  細胞生理学 ,  イオンポンプ ,  H+,K+-ATPase ,  Na+,K+-ATPase ,  トランスポーター ,  イオンチャネル ,  胃酸 ,  がん
Research theme for competitive and other funds  (9):
  • 2022 - 2025 Regulatory mechanisms of the cancer cell survival triggered by intracellular sodium pump present in the vesicles
  • 2022 - 2025 消化器癌における血中循環腫瘍細胞のクラスター化阻害に着目した新規治療開発
  • 2020 - 2023 Regulatory mechanism of calcium signaling in endoplasmic reticulum by novel K+ pump
  • 2017 - 2020 Physiological and pathophysiological properties of Parkinson's disease-related cation pump ATP13A2
  • 2014 - 2017 Novel anti-cancer mechanism of the targeting of the association between receptor-type sodium pump and VSOR channels
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Papers (44):
  • Mizuki Katoh, Takuto Fujii, Yoshiaki Tabuchi, Takahiro Shimizu, Hideki Sakai. Negative regulation of thyroid adenoma-associated protein (THADA) in the cardiac glycoside-induced anti-cancer effect. The journal of physiological sciences : JPS. 2024. 74. 1. 23-23
  • Takuto Fujii, Takahiro Shimizu, Yukino Kaji, Mizuki Katoh, Hideki Sakai. Activation of mouse Otop3 proton channels by Zn2. Biochemical and biophysical research communications. 2023. 658. 55-61
  • Takuto Fujii, Shushi Nagamori, Pattama Wiriyasermkul, Shizhou Zheng, Asaka Yago, Takahiro Shimizu, Yoshiaki Tabuchi, Tomoyuki Okumura, Tsutomu Fujii, Hiroshi Takeshima, et al. Parkinson's disease-associated ATP13A2/PARK9 functions as a lysosomal H+,K+-ATPase. Nature communications. 2023. 14. 1. 2174-2174
  • Takuto Fujii, Takahiro Shimizu, Hideki Sakai. [Novel pathophysiological functions of Na+,K+-ATPases and Cl- channels in cancer cells]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 2023. 158. 6. 465-468
  • Takuto Fujii, Mizuki Katoh, Manami Ootsubo, Oanh T T Nguyen, Mayumi Iguchi, Takahiro Shimizu, Yoshiaki Tabuchi, Yasuharu Shimizu, Hiroshi Takeshima, Hideki Sakai. Cardiac glycosides stimulate endocytosis of GLUT1 via intracellular Na+ ,K+ -ATPase α3-isoform in human cancer cells. Journal of cellular physiology. 2022. 237. 7. 2980-2991
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MISC (8):
  • Taiga Higuchi, Takahiro Shimizu, Takuto Fujii, Noriaki Takeguchi, Bernd Nilius, Hideki Sakai. Modulation of TRPP3 channel function by increasing temperature. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S196-S196
  • Takahiro Shimizu, Yuta Takahashi, Takuto Fujii, Noriaki Takeguchi, Hideki Sakai. The role of Kv7.1 K+ channels in thromboxane A(2)-induced cell proliferation of human colonic cancer cells. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S198-S198
  • Takuto Fujii, Yuji Takahashi, Kyosuke Fujita, Takahiro Shimizu, Noriaki Takeguchi, Hideki Sakai. Chloride-proton antiporter ClC-5 is functionally associated with gastric proton pump. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S218-S218
  • Takuto Fujii, Kazuto Shibuya, Eri Shimoda, Takahiro Shimizu, Noriaki Takeguchi, Kazuhiro Tsukada, Hideki Sakai. Properties of ouabain-insensitive Na+-ATPase activity in human liver cells. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2010. 60. S106-S106
  • Kyosuke Fujita, Takahiro Shimizu, Takuto Fujii, Noriaki Takeguchi, Hideki Sakai. The role of Cl- on membrane potentials in parietal cells of mechanically isolated mouse gastric glands. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2010. 60. S81-S81
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