Rchr
J-GLOBAL ID：202201006393846495
Update date: Apr. 15, 2024
Koba Hayato
コバ ハヤト | Koba Hayato
Affiliation and department：
Research keywords (2)：
Liquid biopsy
, 肺癌
Research theme for competitive and other funds (3)：
- 2023 - 2027 Establishment of histological transformation model from lung small cell carcinoma from adenocarcinoma to explore the therapeutic strategies of small cell lung carcinoma.
- 2023 - 2026 Study to form a theoretical basis for personalized medicine that stratifies EGFR-mutated lung cancer by co-mutations
- 2022 - 2024 Genomic profile and RNA expression analysis for precision medicine of adjuvant therapy after lung cancer operation using pre-operative liquid biopsy
Papers (26)：
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Hayato Koba, Taro Yoneda, Hiroko Morita, Hideharu Kimura, Yuya Murase, Nanao Terada, Yuichi Tambo, Masafumi Horie, Kazuo Kasahara, Isao Matsumoto, et al. Genomic evolutional analysis of surgical resected specimen to assess osimertinib as a first-line therapy in two patients with lung cancer harboring EGFR mutation: Case series. Thoracic Cancer. 2024
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武藤 篤, 渡辺 知志, 加瀬 一政, 村瀬 裕哉, 築田 紗矢, 本江 真人, 山本 祥博, 岩淵 佑, 古林 崇史, 佐伯 啓吾, et al. 間質性肺疾患に対するニンテダニブ効果予測因子の検討. 日本呼吸器学会誌. 2023. 12. 増刊. 216-216
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古林 崇史, 原 丈介, 村瀬 裕哉, 築田 紗矢, 本江 真人, 山本 祥博, 清家 悠樹, 原 椋, 加瀬 一政, 武田 仁浩, et al. 当院での喘息患者の病診・病病連携の現状. 日本呼吸器学会誌. 2023. 12. 増刊. 288-288
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Taro Yoneda, Takashi Sone, Hayato Koba, Kazuhiko Shibata, Junya Suzuki, Mayuko Tani, Masaru Nishitsuji, Koichi Nishi, Takafumi Kobayashi, Hiroki Shirasaki, et al. Long-Term Survival of Patients With Non-Small Cell Lung Cancer Treated With Immune Checkpoint Inhibitor Monotherapy in Real-World Settings. Clinical lung cancer. 2022. 23. 6. 467-476
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Hayato Koba, Hideharu Kimura, Taro Yoneda, Naohiko Ogawa, Kota Tanimura, Yuichi Tambo, Takashi Sone, Kazuyoshi Hosomichi, Atsushi Tajima, Kazuo Kasahara. NOTCH alteration in EGFR-mutated lung adenocarcinoma leads to histological small-cell carcinoma transformation under EGFR-TKI treatment. Translational lung cancer research. 2021. 10. 11. 4161-4173
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MISC (9)：
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木場 隼人, 木村 英晴, 丹保 裕一, 曽根 崇, 笠原 寿郎. 腫瘍内不均一性とctDNAの関連. 肺癌. 2017. 57. 5. 458-458
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Hayato Koba, Hideharu Kimura, Shingo Nishikawa, Taro Yoneda, Takashi Sone, Kazuo Kasahara. Detection of T790M mutation in EGFR gene, an EGFR-TKI resistant mutation, in tumor samples unexposed to EGFR TKIs. CANCER RESEARCH. 2016. 76
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Hayato Koba, Taro Yoneda, Shingo Nishikawa, Takashi Sone, Hideharu Kimura, Kazuo Kasahara. Correlation between EGFR mutation T790M predominancy in initial biopsy detected by droplet digital PCR and acquired resistant mechanism to EGFR TKI. JOURNAL OF CLINICAL ONCOLOGY. 2016. 34. 15
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酒井 珠美, 原 丈介, 小川 尚彦, 谷村 航太, 木場 隼人, 渡辺 知志, 米田 太郎, 西川 晋吾, 高戸 葉月, 曽根 崇, et al. COPDとAsthma-COPD over syndrome(ACOS)における肺癌の組織型、EGFR遺伝子変異の比較. 日本呼吸器学会誌. 2016. 5. 増刊. 296-296
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Hayato Koba, Shingo Nishikawa, Taro Yoneda, Takashi Sone, Hideharu Kimura, Kazuo Kasahara. Squamous cell histological transformation beyond EGFR TKI treatment against EGFR-mutant lung adenocarcinoma. ANNALS OF ONCOLOGY. 2015. 26. 138-138
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Professional career (1)：
- Doctor of Philosophy in Medical Science (Kanazawa University)
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