Kubota Takashi

クボタタカシ | Kubota Takashi

Affiliation and department：

Research field (4)： Pharmacology , Pharmacology , Neuropathology , Biophysics

Research keywords (5)：アルツハイマー病 , パーキンソン病 , 神経変性疾患 , 行動薬理学 , 記憶・学習

Research theme for competitive and other funds (4)：

2016 - 2020 Learning and Memory Performance of Alzheimer Disease Mouse Model with Mutant Human Tau Protein
2012 - 2016 An Attempt to Detect a Neural Activity Change during Eyeblink Conditioning in Monkeys with PET Imaging
2007 - 2008 マウス瞬目反射学習に小脳は不要か?
2005 - 2008 A study on molecular and neural mechanism of eyeblink conditioning

Papers (13)：

Daiki Ojima, Yoko Tominaga, Takashi Kubota, Atsushi Tada, Hiroo Takahashi, Yasushi Kishimoto, Takashi Tominaga, Tohru Yamamoto. Impaired Hippocampal Long-Term Potentiation and Memory Deficits upon Haploinsufficiency of MDGA1 Can Be Rescued by Acute Administration of D-Cycloserine. International Journal of Molecular Sciences. 2024. 25. 17. 9674-9674
Rei Honda, Yuki Matsubara, Takashi Kubota, Hirofumi Konno, Yutaka Kirino, Yasushi Kishimoto. A Bibliometric Analysis of Research Paper Productivity of Japanese Pharmacy Schools. YAKUGAKU ZASSHI. 2023. 143. 3. 317-321
Takashi Kubota, Yutaka Kirino. Age-dependent impairment of memory and neurofibrillary tangle formation and clearance in a mouse model of tauopathy. Brain Research. 2021. 1765. 147496-147496
Masahisa Matsumura, Kana Sato, Takashi Kubota, Yasushi Kishimoto. Spatial and latent memory data in PS2Tg2576 alzheimer's disease mouse model after memantine treatment. Data in Brief. 2021. 36. 107131-107131
Md Razib Hossain, Mostofa Jamal, Yu Tanoue, Daiki Ojima, Hiroo Takahashi, Takashi Kubota, Tuba M. Ansary, Asuka Ito, Naoko Tanaka, Hiroshi Kinoshita, et al. MDGA1-deficiency attenuates prepulse inhibition with alterations of dopamine and serotonin metabolism: An ex vivo HPLC-ECD analysis. Neuroscience Letters. 2020. 716. 134677-134677

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MISC (5)：

Kishimoto Y, Matsumura M, Sato K, Kubota T. Spatial and latent memory data in PS2Tg2576 Alzheimer’s disease mouse model after memantine treatment. Mendeley Data. 2021
多田篤史, 田之上優, 黒川直弘, 津島希海, 尾嶋大喜, Hossain MD Razib, 小坂信二, 芳地一, 窪田剛志, 高橋弘雄, et al. シナプス形成抑制因子MDGA1の欠失による精神神経疾患様行動異常と、これを抑止する薬剤の探索. 日本薬学会年会要旨集. 2020. 140年会. 28P-am125
KURIHARA NAOKAZU, KIRINO YUTAKA, KUBOTA TAKASHI, KISHIMOTO YASUSHI. All-transレチノイン酸の短期的投与がアルツハイマー病モデルマウスの認知・行動に及ぼす効果. 日本薬学会年会要旨集(CD-ROM). 2015. 135th. 3. ROMBUNNO.28PB-PM289-199
KISHIMOTO YASUSHI, SHISHIDO HAJIME, KUBOTA TAKASHI, UENO MASAKI, TAMIYA TAKASHI, KAWAI NOBUYUKI, KIRINO YUTAKA. アルツハイマー病モデルマウスの認知機能に対する外傷性脳損傷の影響. 日本薬学会年会要旨集(CD-ROM). 2014. 134th. 3. ROMBUNNO.28PMM-096-149
Kubota Takashi, Kirino Yutaka. 3P335 Involvement of arachidonic acid cascade in morphine dependence(Behavior,Poster Presentations). Seibutsu Butsuri. 2007. 47. 1. S286

Books (3)：

Lectures and oral presentations (50)：

A Cuprizone-induced neuroinflammation;mouse model with;prepulse inhibition deficit exhibited a complementary;yrosine hydroxylase abundance ratio in;he prefrontal cortex;midbrain
(2022)
Behavioral disorders and expression changes of the tyrosine hydroxylase in Cuprizone-induced neuroinflammation mouse model with schizophrenia-like symptoms
(Neuroscience 2002)
Cuprizone短期投与によりプレパルス抑制が障害されたマウスにおける統合失調症関連分子の免疫組織学的研究
(日本神経科学学会・日本神経化学会・日本神経回路学会合同大会合同年会)
シナプス形成抑制因子MDGA1/2の欠失は対蹠的な興奮/抑制バランス偏移と行動異常を引き起こすが、成年期の薬剤投与により回復できる
(Neuro 2022 2022)
ジャワショウガ抽出物trans-bangleneのタウオパチーモデルマウスの記憶障害に対する効果
(第95回日本薬理学会年会 2022)

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Education (3)：

Professional career (1)：

Work history (5)：

Committee career (2)：

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