Rchr
J-GLOBAL ID：202201006510744674
Update date: Nov. 16, 2024
Sakai Katsuyuki
サカイ カツユキ | Sakai Katsuyuki
Affiliation and department：
Job title：
Postdoctoral Researcher
Research field (1)：
Applied microbiology
Research keywords (4)：
天然物化学
, 生理活性物質
, 構造解析
, 放線菌
Research theme for competitive and other funds (1)：
- 2022 - 2026 Establishment of platform for creation of novel bioactive natural products by expression of latent functions of microorganisms
Papers (14)：
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Aoi Kimishima, Atsuka Nishitomi, Iori Tsuruoka, Masako Honsho, Sota Negami, Sota Honma, Katsuyuki Sakai, Toshiyuki Tokiwa, Hiroki Kojima, Kenichi Nonaka, et al. Synthesis and biological evaluation of burnettiene A derivatives enabling discovery of novel fungicide candidates. Journal of pesticide science. 2024. 49. 3. 159-167
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Yu Zheng, Katsuyuki Sakai, Kohei Watanabe, Hiroshi Takagi, Yumi Sato-Shiozaki, Yuko Misumi, Yohei Miyanoiri, Genji Kurisu, Toshihiko Nogawa, Ryo Takita, et al. Iron-sulphur protein catalysed [4+2] cycloadditions in natural product biosynthesis. Nature Communications. 2024. 15. 1
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Aoi Kimishima, Atsuka Nishitomi, Iori Tsuruoka, Katsuyuki Sakai, Rei Hokari, Masako Honsho, Sota Honma, Yuki Ono, Naozumi Kondo, Hayama Tsutsumi, et al. Discovery of an antimalarial compound, burnettiene A, with a multidrug-sensitive Saccharomyces cerevisiae screening system based on mitochondrial function inhibitory activity. Bioscience, Biotechnology, and Biochemistry. 2024. 88. 10. 1212-1216
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Katsuyuki Sakai, Yushi Futamura, Toshihiko Nogawa, Yuzhu Zhao, Hiroyuki Koshino, Hiroyuki Osada, Shunji Takahashi. Production of Kinanthraquinone D with Antimalarial Activity by Heterologous Gene Expression and Biotransformation in Streptomyces lividans TK23. Journal of Natural Products. 2024. 87. 4. 855-860
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Aoi Kimishima, Daichi Hagimoto, Masako Honsho, Katsuyuki Sakai, Sota Honma, Shin-Ichi Fuji, Masato Iwatsuki, Toshiyuki Tokiwa, Kenichi Nonaka, Takumi Chinen, et al. Total Synthesis of Fusaramin, Enabling Stereochemical Elucidation, Structure-Activity Relationship, and Uncovering the Hidden Antimicrobial Activity against Plant Pathogenic Fungi. Organic letters. 2024. 26. 3. 597-601
ｍore...
Lectures and oral presentations (18)：
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Kinanthraquinone生合成機構の解析
(第38回 (2024年度) 日本放線菌学会大会 2024)
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ミトコンドリア機能阻害剤fusaraminの全合成による立体化学構造の決定、構造活性相関の解明、新規抗真菌活性の発見
(日本農芸化学会2024年度大会 2024)
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異種発現Streptomyces lividans TK23を利用した新規アンスラキノン化合物の取得
(日本農芸化学会2024年度大会 2024)
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A Combination Strategy of Multidrug-Sensitive Budding Yeast and Chemical Modifications Enabling to Find a New Overlooked Antifungal Compound, Sakurafusariene, from In-House Fractionated Library
(5th KRIBB-RIKEN Chemical Biology Joint Symposium 2023)
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Engineering of Cytochrome P450 for Synthesis of Novel Reveromycin Derivatives
(5th KRIBB-RIKEN Chemical Biology Joint Symposium 2023)
ｍore...
Education (3)：
- 2017 - 2020 Kitasato University Graduate School of Infectioncontrol Sciences
- 2015 - 2017 Kitasato University Graduate School of Infectioncontrol Sciences
- 2011 - 2015 Kitasato University School of Science Department of Chemistry
Work history (1)：
- 2020/04 - 現在 RIKEN RIKEN Center for Sustainable Resource Science Postdoctoral researcher
Awards (1)：
- 日本農芸化学会 日本農芸化学会2018年度大会トピックス賞 薬剤感受性出芽酵母を用いた抗真菌薬シード化合物の探索
Association Membership(s) (2)：
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