Onuma Kunishige

オヌマクニシゲ | Onuma Kunishige

Affiliation and department：
Job title： Program-Specific Assistant Professor
Homepage URL (1)： https://cbrrd.med.kyoto-u.ac.jp/
Research theme for competitive and other funds (9)：

2024 - 2027 Establishment of photodynamic therapy for deep cell tumors using the up-conversion method
2023 - 2027 Micropapillary carcinomaの極性転換を標的とした治療戦略
2023 - 2026 新しい細胞集塊薬剤浸透性評価モデルの開発
2022 - 2024 Mechanisms of the immune evasion through polarity switching of the colorectal cancer clusters
2020 - 2023 The mechanism of polarity switching in the cluster of human colorectal adenocarcinoma during the process of metastasis

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Papers (53)：

Yi-Kai Lin, Roberto Coppo, Kunishige Onuma, Hiroko Endo, Jumpei Kondo, Sadahiro Iwabuchi, Shinichi Hashimoto, Yoshiro Itatani, Kazutaka Obama, Masahiro Inoue. Growth pattern of de novo small clusters of colorectal cancer is regulated by Notch signaling at detachment. Cancer Science. 2024
Masamune Masuda, Keita Iida, Sadahiro Iwabuchi, Mie Tanaka, Satoshi Kubota, Hiroyuki Uematsu, Kunishige Onuma, Yoji Kukita, Kikuya Kato, Shoji Kamiura, et al. Clonal Origin and Lineage Ambiguity in Mixed Neuroendocrine Carcinoma of the Uterine Cervix. The American Journal of Pathology. 2024
松浦吉晃, 小沼邦重, 下村雅律, 岡田悟, 内堀篤樹, 井上匡美, 井上正宏. Spread Through Air Spacesにおけるがん細胞塊極性の役割. 日本胸部外科学会定期学術集会. 2023. 76回. LOP4-1
松浦吉晃, 小沼邦重, 下村雅律, 岡田悟, 内堀篤樹, 井上匡美, 井上正宏. Spread Through Air Spacesにおけるがん細胞塊極性の役割. 日本胸部外科学会定期学術集会. 2023. 76回. LOP4-1
コッポ・ロベルト, 近藤純平, 小沼邦重, 井上正宏. 機能的な単一細胞解析による大腸癌内の相互転換可能な細胞亜集団の解明(Distinct but interchangeable subpopulations of colorectal cancer cells with different growth fates and drug sensitivity). 日本癌学会総会記事. 2023. 82回. 986-986

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MISC (62)：

小沼邦重, 近藤純平, 井上正宏. 大腸がん転移におけるがん細胞集団の極性転換の役割. 日本癌学会総会記事. 2021. 80回. [P20-2]
Mie Tanaka, Jumpei Kondo, Kensuke Kaneko, Hiroko Endo, Kunishige Onuma, Roberto Coppo, Masamune Masuda, Shoji Kamiura, Kiyoshi Yoshino, Yutaka Ueda, et al. Heterogenous chemosensitivity of a panel of organoid lines derived from small cell neuroendocrine carcinoma of the uterine cervix (Mar, 10.1007/s13577-021-00511-5, 2021). HUMAN CELL. 2021. 34. 3. 1028-1030
小沼邦重, 近藤純平, 井上正宏. 大腸がん転移におけるがん細胞集団の極性転換の役割. 日本癌学会総会記事. 2020. 79回. OJ10-2
小沼邦重, 近藤純平, 井上正宏. Micropapillary carcinoma病態における極性転換とその分子機構(Molecular mechanism of polarity switching in micropapillary carcinoma). 日本癌学会総会記事. 2019. 78回. P-1005
石川瑞穂, 尾崎充彦, 尾崎充彦, 山岸誠, 小沼邦重, 井藤久雄, 井藤久雄, 岡田太, 岡田太, 遠藤英也. 血管内皮細胞に発現しているMTA1はS100A4を介する事で新たな腫瘍血管新生の阻害標的になりうる. 日本病理学会会誌. 2019. 108. 1. 330-330

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Professional career (1)：

Doctor of Medical Science (Yamagata University)

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