Rchr
J-GLOBAL ID：202201007614296181
Update date: Sep. 26, 2024
OOTANI TAKUYA
オオタニ タクヤ | OOTANI TAKUYA
Affiliation and department：
Job title：
Assistant Professor
Research field (1)：
Pharmaceuticals - chemistry and drug development
Research keywords (1)：
Pharmaceutical science
Research theme for competitive and other funds (2)：
- 2024 - 2026 Development of novel radiotheranostics drugs based on EGFR binding peptides
- 2022 - 2024 Development of novel photoimmunotherapy drugs using peptides as target-directed molecules
Papers (3)：
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Otani T, Suzuki M, Takakura H, Hanaoka H. Synthesis and biological evaluation of EGFR binding peptides for near-infrared photoimmunotherapy. Bioorganic & medicinal chemistry. 2024. 105. 117717
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Takuya Otani, Yasunao Hattori, Kenichi Akaji, Kazuya Kobayashi. Macrocyclic BACE1 inhibitors with hydrophobic cross-linked structures: Optimization of ring size and ring structure. Bioorganic & medicinal chemistry. 2021. 52. 116517-116517
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Kazuya Kobayashi, Takuya Otani, Saki Ijiri, Yuki Kawasaki, Hiroki Matsubara, Takahiro Miyagi, Taishi Kitajima, Risa Iseki, Katsuyasu Ishizawa, Naoka Shindo, et al. Structure-activity relationship study of hydroxyethylamine isostere and P1' site structure of peptide mimetic BACE1 inhibitors. Bioorganic & medicinal chemistry. 2021. 50. 116459-116459
MISC (1)：
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大谷 拓也, 花岡 宏史. EGFR結合ペプチドの光免疫療法薬としての利用. 細胞. 2024. 56. 7. 536-538
Lectures and oral presentations (1)：
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EGFR結合ペプチドを用いた新規光免疫療法薬の開発研究
(第40回メディシナルケミストリーシンポジウム 2023)
Education (2)：
- 2018 - 2022 Kyoto Pharmaceutical University Graduate School, Division of Pharmaceutical Sciences Department of Pharmacy
- 2012 - 2018 Kyoto Pharmaceutical University Faculty of Pharmaceutical Science
Professional career (1)：
- Pharmacy, Ph.D (Kyoto Pharmaceutical University)
Awards (1)：
- 2021/04 - The Pharmaceutical Society of Japan Best Student Presentation Award (Oral Presentation Division) Introduction of cross-linked partial branch structures in macrocyclic BACE1 inhibitors
Association Membership(s) (2)：
The Japanese Peptide Society
, The Pharmaceutical Society of Japan
