Rchr
J-GLOBAL ID：202201008543365884
Update date: May. 08, 2024
Yoshino Ryunosuke
ヨシノ リュウノスケ | Yoshino Ryunosuke
Affiliation and department：
Job title：
Assistant Professor
Research keywords (1)：
Computational Chemistry, Molecular Simulation
Research theme for competitive and other funds (2)：
- 2018 - 2020 Pharmacophore modeling using interaction analysis information by Fragment Molecular Orbital method
- 2016 - 2018 インシリコ技術を用いたシャーガス病治療薬の開発
Papers (24)：
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Kudo, Genki, Yanagisawa, Keisuke, Yoshino, Ryunosuke, Hirokawa, Takatsugu. AAp-MSMD: Amino Acid Preference Mapping on Protein-Protein Interaction Surfaces Using Mixed-Solvent Molecular Dynamics. Journal of chemical information and modeling. 2023. 63. 24. 7768-7777
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Ryunosuke Yoshino, Nobuaki Yasuo, Yohsuke Hagiwara, Takashi Ishida, Daniel Ken Inaoka, Yasushi Amano, Yukihiro Tateishi, Kazuki Ohno, Ichiji Namatame, Tatsuya Niimi, et al. Discovery of a Hidden Trypanosoma cruzi Spermidine Synthase Binding Site and Inhibitors through In Silico, In Vitro, and X-ray Crystallography. ACS Omega. 2023
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Saito, Kenji, Sekiya, Motohiro, Kainoh, Kenta, Yoshino, Ryunosuke, Hayashi, Akio, Han, Song-Iee, Araki, Masaya, Ohno, Hiroshi, Takeuchi, Yoshinori, Tsuyuzaki, Tomomi, et al. Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity. The Journal of biological chemistry. 2023. 299. 7. 104890-104890
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Kudo, Genki, Hirao, Takumi, Yoshino, Ryunosuke, Shigeta, Yasuteru, Hirokawa, Takatsugu. Pocket to concavity: a tool for the refinement of protein-ligand binding site shape from alpha spheres. BIOINFORMATICS. 2023. 39. 4
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Junya Tabata, Takashi Nakaoku, Mitsugu Araki, Ryunosuke Yoshino, Shinji Kohsaka, Ayaka Otsuka, Masachika Ikegami, Ayako Ui, Shin-Ichiro Kanno, Keiko Miyoshi, et al. Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis. Cancer research. 2022. 82. 20. 3751-3762
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MISC (2)：
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Ryunosuke Yoshino, Nobuaki Yasuo, Yohsuke Hagiwara, Kazuki Ohno, Masaya Orita, Masayuki Inoue, Shigeharu Harada, Teruki Honma, Daniel KenInaoka, Kiyoshi Kita, et al. Protein-ligand interaction energy analysis between anti-trypanosome drug candidate and target protein using fragment molecular orbital. IPSJ SIG Notes. 2013. 2013. 5. 1-7
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Ryunosuke Yoshino, Nobuaki Yasuo, Yohsuke Hagiwara, Kazuki Ohno, Masaya Orita, Masayuki Inoue, Shigeharu Harada, Teruki Honma, Daniel KenInaoka, Kiyoshi Kita, et al. Protein-ligand interaction energy analysis between anti-trypanosome drug candidate and target protein using fragment molecular orbital. IPSJ SIG technical reports. 2013. 2013. 5. 1-7
Lectures and oral presentations (9)：
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Amino acid preference mapping on protein-protein interaction surface using mixed-solvent molecular dynamics
(CBI学会2022年大会)
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Molecular Dynamics for Visualization of Amino Acid Residue Interaction Profile of Molecular Probes
(日本生物物理学会第60回年会)
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DNAメチル基転移酵素阻害剤のアイソフォーム選択性の解明
(日本コンピュータ化学会2021年 秋季年会 2021)
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Prediction of binding mechanism for DNA methyltransferase 3A selective inhibitor using molecular simulation approach
(CBI学会2021年大会 2021)
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分子シミュレーション技術を用いたタンパク質-リガンド間の分子認識メカニズムの解析
(第43回日本分子生物学会年会 2020)
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Professional career (1)：
- Doctor of Agriculture (Graduate School of Agricultural and Life Sciences, The University of Tokyo)
Work history (1)：
- 2017/04 - 2018/03 Tokyo Institute of Technology Education Academy of Computational Life Sciences Specially Appointed Assistant Professor
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