Research keywords (5)：
skeletal biology・regenerative medicine・tissue engineering
, Biomaterials science
, public health
, artificial intelligence
, Innovation management
Research theme for competitive and other funds (56)：
2021 - 2025 ヒト骨発生機構の理解に基づく組織再生研究基盤の構築
2021 - 2023 Development of bone regeneration methods based on understanding of tissue remodeling
2017 - 2021 Fundamental study of bone regeneration with site-specific epigenome editing
2016 - 2021 Development of 4-dimensional scaffold system that integrates signaling factors and 3-dimensional structural biomaterials
2016 - 2019 Novel three-dimensional bone regenerative medicine strategy using human dental pulp stem cells
2016 - 2019 Exploring a novel strategy for osteoporosis treatment through osteoclast-osteoblast interaction.
2014 - 2019 Development of a novel strategy for bone regeneration with small molecule-mediated osteo-reprogramming and understanding of genomic mechanisms underlying the process
2015 - 2018 Elucidation of the inhibitory mechanism of histamine H2 receptor antagonist against posterior longitudinal ligament ossification
2015 - 2018 Identification of the molecular network regulating movement of Hedgehog proteins on cell surface during skeletal development
2014 - 2018 Dynamics of epigenome and transcription during the Hedgehog signaling-mediated specification of skeletal cells
2016 - 2017 mRNA送達機能構造材料を用いた骨・軟骨再生法の開発に関する基礎的検討
2014 - 2017 Biological activities and drug development of natural compounds with bone-resorbing and bone-forming properties during bone metabolism
2014 - 2017 Strategic research on development of bone regenerative therapy with in vivo delivery of nucleic acids
2013 - 2017 Strategic research of osteoarthritis for novel therapeutics
2013 - 2016 Creation of a rat model of the periodontal disease, and research of the bone regeneration treatment using the osteogenic small chemical compound
2012 - 2016 Development of bone-inducing artificial bone
2014 - 2015 低分子化合物を用いた骨ダイレクトリプログラミングによる新規骨再生技術の開発
2013 - 2015 Development of Innovative Intubation Tube inducing Less-Ventilator-associated pneumonia
2013 - 2015 Genome-wide study of Wnt/b-catenin-mediated differentiation and maintenance of stemness
2011 - 2014 Examination of hybrid bone grafts using nano DDS and artificial bones
2011 - 2014 Optimization of the bone regeneration system using small molecules and examination of its molecular mechanisms
2011 - 2013 Developing strategies to obtain regulatory approval for therapies from Japanese universities and startups
2011 - 2013 Elucidation of tendon calcification inhibition mechanism of histamine H2-receptor antagonist
2011 - 2013 The mechanism of interaction with parathyroid hormone/parathyroid hormone-related protein receptor signals and Wnt/b-catenin in osteo-remodeling tooth migration model
2010 - 2012 脂質代謝調節因子アディポカインによる軟骨代謝調節機構の検討
2008 - 2011 Development of high performance artificial bone
2007 - 2011 The integrated study for molecular backgrounds and therapeutic targets of osteoarthritis : The ROAD project.
2009 - 2010 生体膜保護作用を利用した革新的炎症抑制デバイスの開発
2008 - 2010 Strategic research for the identification of novel osteogenic small compounds and their application to bone regeneration
2007 - 2009 Strategic development of a novel implant system to achieve bone regeneration without cell transplantation
2007 - 2009 新規軟骨分化誘導因子ZSCANCの機能解析
2006 - 2009 Research of the Molecular Network Regulating Endochondral Ossification
2007 - 2008 Role of Hedgehog-Patched1 signaling pathway on orthodontic tooth movement and bone remodeling
2006 - 2008 Research of 3D bone model for surgical simulation
2006 - 2008 X型コラーゲンプロモーター解析による軟骨細胞肥大化の分子メカニズム
2006 - 2008 ナノテクノロジーを利用した骨誘導性デンタルインプラントシステムの開発
2005 - 2008 The molecular mechanism of PTH anabolic action on bone
2006 - 2007 生理的・病的条件下におけるヘッジホッグシグナルによる骨代謝調節機構の解明
2005 - 2007 Development of multi-functional nanocarrier of siDNA and application for bone and joint diseases
2005 - 2007 Identification of the minimal and sufficient signaling unit for bone formation and development of bone system using skin fibroblasts
2005 - 2006 Experimental study of tendon adhesion prevention by a biocompatible polymer hydrogel.
2005 - 2006 Expression Cloning of Joint Regenerative Genes
2005 - 2006 The analysis of the mechanism of chondrocyte differentiation and apoptosis
2004 - 2006 Strategic Research for Upstream Molecules, Target molecules and Co-factors of the SOX trio, the Essential Transcription Factors for Chondrogenesis
2004 - 2006 Research and Development for Fabrication of 3D-structured Tissue-engineered Cartilage through Nino-molecular Technologies
2003 - 2006 Research on Pathophysiology and Novel Treatment of Osteoarthritis through Molecular Biological Approach
Dahlia Eldeeb, Hiroyuki Okada, Yutaka Suzuki, Masahide Seki, Junichi Tanaka, Kenji Mishima, Ung-Il Chung, Shinsuke Ohba, Hironori Hojo. Exploring the Role of DNMT1 in Dental Papilla Cell Fate Specification during Mouse Tooth Germ Development through Integrated Single-Cell Transcriptomics and Bulk RNA Sequencing. Journal of oral biosciences. 2024
Olivia Sjöland, Thomas Svensson, Kaushalya Madhawa, Hoang NT, Ung-Il Chung, Akiko Kishi Svensson. Associations of Subjective Sleep Quality with Wearable Device-Derived Resting Heart Rate During REM Sleep and Non-REM Sleep in a Cohort of Japanese Office Workers. Nature and Science of Sleep. 2024. Volume 16. 867-877
1993 - 1997 The University of Tokyo Graduate School of Medicine
1985 - 1989 The University of Tokyo Faculty of Medicine School of Medicine
1983 - 1985 The University of Tokyo College of Arts and Sciences
Work history (11)：
2021/04 - 現在 Kanagawa University of Human Services Vice President・Executive Board Member
2019/04 - 現在 Kanagawa University of Human Services School of Health Innovation Dean
2016/11 - 現在 The University of Tokyo Graduate School of Medicine Center for Disease Biology and Integrative Medicine Professor
2007/03 - 現在 The University of Tokyo The Graduate School of Engineering Department of Bioengineering Professor
2005/01 - 2007/02 The University of Tokyo Graduate School of Medicine Center for Disease Biology and Integrative Medicine Associate Professor
2002/07 - 2004/12 The University of Tokyo Graduate School of Medicine
2001/09 - 2002/06 Harvard Medical School Assistant Professor
1998/09 - 2001/08 Harvard Medical School Instructor
1995/10 - 1998/08 Harvard Medical School Massachussetts General Hospital Research Fellow
1991/06 - 1993/03 The University of Tokyo Faculty of Medicine University Hospital Clinical Fellow
1989/06 - 1992/05 The University of Tokyo Faculty of Medicine University Hospital Resident
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Awards (13)：
2020/02 - The University of Tokyo Graduate School of Engineering Dean's Award Outstanding contributions to globalization and efficient acquisition of external funding
2016/09 - The International College of Fellows-Biomaterials Science and Engineering (ICF-BSE) Fellow of Biomaterials Science and Engineering(FBSE)
2009/04 - 財団法人金萬有科学振興会 学術賞
2009/04 - Japanese Society for Bone and Mineral Research Academic Award (Basic Research)
2008/04 - Japanese Society for Biomaterials Society Award
2007/04 - Japanese Society for Artificial Organs Paper Award
2007/04 - Terumo Specified Research Grant
1999/09 - American Society for Bone and Mineral Research John Haddad Young Investigator Award
1998/09 - The Medical Foundation The Medical Foundation Award
1998/09 - American Society for Bone and Mineral Research Travel Award
1997/09 - American Society for Bone and Mineral Research Young Investigator Award
1997/09 - Massachussetts General Hospital Medical Discovery Award
1986/04 - Goethe Institute Premium Scholarship
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Association Membership(s) (3)：
Japanese Society of Public Health
, Japanese Society for Biomaterials
, Japanese Society for Regenerative Medicine
